| DCC4105 |
Pf-562771 |
Novel potent and selective inhibitor of the activation-loop mutant Kit phosphorylation and tumor growth |
|
| DCC4106 |
Pf-68742 |
Novel Entry Inhibitor of both CCR5- and CXCR4-Tropic Strains of Human Immunodeficiency Virus Type 1 (HIV-1), Targeting a Novel Site on gp41 |
|
| DCC4107 |
Pf-7006 |
Highly selective, extremely potent Mps1 kinase inhibitor |
|
| DCC4108 |
Pf-alkyne |
Novel fluorophosphonate-based probe, specifically and covalently reacts with the tyrosine-111 residue of the Schistosoma japonicum GST (sjGST) tag, rapidly and site-selectively immobilizes sjGST fusion proteins |
|
| DCC4109 |
Pf-cbp/brd4 |
Novel dual CBP/p300 and BRD4 bromodomain inhibitor, downregulating IL-6, IL-ß and IFN-ß in macrophages |
|
| DCC4110 |
Pfi-7n |
Negative control for PFI-7 (GLXC012596) |
|
| DCC4111 |
Pfkrs1-in-5 |
Novel selective inhibitor of both Plasmodium and Cryptosporidium lysyl-tRNA synthetase, clearing parasites from mouse models of malaria and cryptosporidiosis infection. |
|
| DCC4112 |
Pfn1-in-c1 |
Novel inhibitor of Profilin1 (Pfn1), reducing the overall level of cellular filamentous (F)-actin, slowing EC migration and proliferation, and inhibiting the angiogenic ability of EC both in vitro and ex vivo |
|
| DCC4113 |
Pfn1-in-c2 |
Novel inhibitor of Profilin1 (Pfn1), reducing the overall level of cellular filamentous (F)-actin, slowing EC migration and proliferation, and inhibiting the angiogenic ability of EC both in vitro and ex vivo |
|
| DCC4114 |
Pg490-88 |
Water soluble derivative pro-drug of PG490 (triptolide) |
|
| DCC4115 |
Pg-928310 |
Novel anti-HIF-1alpha agent |
|
| DCC4116 |
Pg97-269 Tfa Salt |
Potent and selective antagonist of the VIP1 receptor, inhibiting competitively effect of VIP on the VIP1 receptor mediated stimulation of adenylate cyclase activity with Ki values respectively of 15 ± 5 nM and 2 ± 1 nM for the rat and human VIP1 receptor |
|
| DCC4117 |
Pgam1 Inhibitor Kh2 |
Novel allosteric PGAM1 inhibitor, showing efficacious in multiple preclinical models of pancreatic ductal adenocarcinoma (PDAC), especially with high PGAM1 expression |
|
| DCC4118 |
Pgam1 Inhibitor Kh3 |
Novel allosteric PGAM1 inhibitor, showing efficacious in multiple preclinical models of pancreatic ductal adenocarcinoma (PDAC), especially with high PGAM1 expression |
|
| DCC4119 |
Pge-2946979 |
Novel potent matrix metalloproteinase (MMP) inhibitor, targeting MMPs 1, 3, 9, and 13 (24, 18, 1.9, and 1.3 nM, respectively) |
|
| DCC4120 |
Pgmi-004a |
Glycolytic enzyme phosphoglycerate mutase 1 (PGAM1) inhibitor |
|
| DCC4122 |
pha-680626 |
Inhibitor of both Bcr-Abl tyrosine kinase and Aurora kinases |
|
| DCC4123 |
Pha-e429 |
Selective ATP competitive ALK inhibitor |
|
| DCC4124 |
Phagocytosis Inhibitor |
Inhibitor of phagocytosis, interacting with and inhibiting the activating Fc receptors on macrophages, inhibiting downstream signaling pathways driving Fc-mediated phagocytosis |
|
| DCC4125 |
Phantasmidine |
Natural nicotinic acetylcholine receptor agonist |
|
| DCC4126 |
Phar-095239 |
Novel COX-2 inhibitor |
|
| DCC4127 |
Phencyclidine Hydrochloride |
Inhibitor of NMDA receptors, used as a veterinary anesthetic, and briefly as a general anesthetic for humans |
|
| DCC4128 |
Phen-dc3 |
Selective ligand of a specific G-quadruplex conformation, interacting with the quadruplex through extensive |
|
| DCC4129 |
phenoxodiol Diacetate |
Prodrug of phenoxodiol |
|
| DCC4130 |
Phenylarsine Oxide |
Inhibitor of internalization of cell surface receptors and tyrosine phosphatases, with no effect on tyrosine kinase |
|
| DCC4131 |
phenylmethimazole |
Blocker of dsRNA-induced IRF3 nuclear translocation and homodimerization; Inhibitor of lipopolysaccharide-mediated Toll-like receptor-4 signaling; Inhibitor of human pancreatic cancer |
|
| DCC4132 |
Phnp-3 |
Novel selective α-syn ligand, exhibited the promising binding characteristics for α-syn aggregates (Ki = 0.52 nM) |
|
| DCC4133 |
Phoenixin-14 |
Novel neuropeptide, protecting human brain vascular endothelial cells against oxygen-glucose deprivation/reoxygenation (OGD/R)-induced inflammation and permeability, significantly ameliorating HFD-induced obesity and fatty liver, regulating pituitary gona |
|
| DCC4134 |
Phoenixin-20 |
Novel GPR173 agonist, promoting osteoblastic differentiation of MC3T3-E1 cells. stimulating mRNAs encoding hypothalamo-pituitary-gonadal hormones |
|
| DCC4135 |
Phomoxanthone A |
Natural anti-tumor agent, showing strong apoptotic anticancer effects against platinum-resistant solid cancers |
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