DCC4171 |
Piperazinomycin |
Antifungal antibiotic, showing inhibitory activity against fungi and yeasts, especially against Trichophyton |
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DCC4172 |
Piperidol B2 |
Novel potent in vitro and in vivo antifungal agent against azole-resistant Candida albicans |
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DCC4173 |
Piperneolignan A |
Natural nitric oxide (NO) production inhibitor |
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DCC4174 |
Piroxicam-ß-cyclodextrin |
NSAID with better gastrointestinal (GI) tolerability |
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DCC4175 |
Pitofenone |
Inhibitor of the acetylcholinesterase activity from bovine erythrocytes and electric eel |
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DCC4176 |
Pixantrone |
Inhibitor of topoisomerase II, intercalating into DNA and inducing topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity |
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DCC4177 |
Pk5196 |
Potent ligand to target the Y220C pocket, stabilizing Y220C |
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DCC4178 |
Pkc-iota-in-19 |
Novel Protein Kinase C-iota (PKC-ι) Inhibitor, Binding Post-kinase Domain Residues |
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DCC4179 |
Pkcθ-in-41 |
Novel selective inhibitor of protein kinase Cθ (PKCθ) |
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DCC4180 |
Pkm2-in-8 |
Novel highly potent and selective PKM2 inhibitor, blocking PKM2 mitochondrial translocation under nutritional stress and inhibits tumor growth in vivo |
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DCC4181 |
Pks21272 |
Novel potent and specific β5i inhibitor |
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DCC4182 |
Pkumdl-ltq-301 |
Potent inhibitor of HipA toxin, inhibiting E. coli persistence |
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DCC4183 |
Pladienolide B |
mRNA splicing inhibitor |
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DCC4184 |
Plafibride |
Antilipidemic and antiplatelet agent |
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DCC4185 |
Plap Inhibitor 16 |
Novel Potent and Specific Inhibitor of Placental Alkaline Phosphatase (PLAP; IC 50 = 32 nM), Targeting Tumor of the Female Reproductive Tract |
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DCC4186 |
Plasiatine |
Novel Potent Activator of the Nonreceptor Protein Tyrosine Phosphatase Shp2 |
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DCC4187 |
Plaunotol |
Gastroprotective agent, increasing the prostaglandin production in the gastric mucosa and accelerates ulcer healing |
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DCC4188 |
Plazomicin |
Broad spectrum aminoglycoside antibiotic typically used for moderate-to-severe urinary tract infections or pyelonephritis |
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DCC4189 |
Plc Inhibitor 3017 |
Novel inhibitor of phospholipase C (PLC) isozyme |
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DCC4190 |
pl-dhn |
Novel enhancer of Reactive Oxygen Species (ROS), depleting glutathione levels in analogy to piperlongumine but with reduced cell death |
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DCC4191 |
Plectranthoic Acid |
Novel activator of AMPK, inducing apoptotic death in prostate cancer cells |
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DCC4192 |
Plhspt |
Plk1 PBD-specific phosphopeptide inhibitor, effectively inhibiting mitotic progression and cell proliferation |
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DCC4193 |
Plk1 Pbd-in-143 |
Novel Inhibitor of the Polo-Box Domain of Polo-like Kinase 1 (Plk1 PBD) |
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DCC4194 |
Plk1-in-7k |
Novel polo-like kinase 1 (PLK1) inhibitor |
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DCC4195 |
Plx647(ome) |
Slightly less potent inhibitor of FMS than PLX647 but has better aqueous solubility |
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DCC4196 |
Pm00104 |
Potent anticancer tetrahydroisoquinoline alkaloid, being able to form a covalent bond with the amino group of a guanine in selected triplets of DNA duplexes and eventually give rise to double-strand breaks |
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DCC4197 |
Pmed-1 |
Novel inhibitor of β-catenin signaling, significantly reduced β-catenin activity in hepatoblastoma and several HCC cells |
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DCC4198 |
Pmmb-317 |
Novel potent irriversible dual inhibitor of tubulin and epidermal growth factor receptor (EGFR), inducing the apoptosis of A549 cells in a dose- and time-dependent manner, along with decrease in mitochondrial membrane potential (MMP), production of ROS an |
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DCC4199 |
Pmpmease-in L-23 |
Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway |
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DCC4200 |
Pmpmease-in L-28 |
Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway |
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