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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC4796 Smcy 5.5 Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy
DCC4797 Smdc818909 Novel Allosteric Inhibitor of p97
DCC4798 Smer10 Novel enhancer of the clearance of mutant aggregate-prone proteins by autophagy in mammalian cell models of Huntington's and Parkinson's disease, independent of rapamycin
DCC4799 S-mgb-234 Bis-tfa Salt Novel strathclyde minor groove binder (S-MGB), curing animal African trypanosomiasis (AAT)
DCC4800 smip001 Novel enhancer of the cyclin-dependent kinase (CDK) inhibitor p27(Kip)
DCC4801 Smip2.1 Novel TLR2 agonist, promoting cross-presentation by mouse and human antigen presenting cells
DCC4802 Smk-17 Novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor
DCC4803 Sml-10-70-1 Selective, direct-acting covalent inhibitor of the K-Ras G12C mutant relative to wild-type Ras
DCC4804 Sml-8-73-1 Novel Active Site Inhibitor of Oncogenic K-Ras G12C
DCC4805 Smn2-stablizer-27 Novel Stablizer of Survival of Motor Neuron 2 (SMN2) , Post-Translationally Stablizing SMN Protein for the Treatment of Spinal Muscular Atrophy (SMA)
DCC4806 Smn-c5 Novel specific splicing enhancer, targeting RNA for a specific splicing correction, recognizing the interface between U1 snRNP and the SMN2 E7 5ʹ SS, promoting the U1-C zinc finger RNA duplex binding activity
DCC4807 Smt022357 Second-generation modulator of utrophin, increasing utrophin expression in skeletal, respiratory and cardiac muscles
DCC4808 Smtp-7 Novel dual inhibitor of thrombolysis and soluble epoxide hydrolase
DCC4809 Smurf1 Inhibitor 1 Novel Smurf1 inhibitor, promoting bone formation in mouse models of distinctive age-related osteoporosis
DCC4811 Sn16713 Selective ligand of GC-rich sequences in DNA
DCC4812 Sn-28049 Novel potent DNA-binding topoisomerase II-directed antitumor agent.
DCC4813 Sn34037 Novel specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188)
DCC4814 Sn-38 Prodrug 3c Novel Bioorthogonal Prodrug of SN-38 with Fast Reaction Kinetics and High Releasing Efficiency In Vivo
DCC4815 Snap-398299 Potent and selective GAL3 antagonist
DCC4816 Snap-5089 Highly selective alpha1A-adrenoceptor antagonist
DCC4817 Sniper(abl)-38 Specific and Nongenetic IAP-dependent Protein Eraser (SNIPER), acting as a protein degradation inducer of oncogenic BCR-ABL protein
DCC4818 Sniper(brd4)-1 Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of bromodomain-containing protein 4 (BRD4)
DCC4819 Sniper(ch6) Novel fused proteins degrader of the His-tagged CRABP-II and Smad2 in cells
DCC4820 Sniper(crabp)-11 Novel potent degrader of the mitochondrial CRABP-II protein
DCC4821 Sniper(er)-87 Novel potent and selective degrader of the ERα protein
DCC4822 Sniper(pde4)-9 Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of phosphodiesterase-4 (PDE4)
DCC4823 Snri-h05 Novel potent serotonin and noradrenaline reuptake inhibitor (SNRI) with moderate 5-HT2A antagonist activity for anti-depression
DCC4824 sns-oh Inducer of apoptosis in neuroblastoma cells through inhibition of AKT signaling pathway
DCC4825 Snu-bp Novel agonist of PPAR-gamma, inhibiting lipopolysaccharide (LPS)-induced NO production and pro-inflammatory cytokines, potentiating interleukin-4-induced arginase-1 expression, promoting microglial polarization toward to an M2 anti-inflammatory phenotype
DCC4826 Snx2-1-108 Highly selective inhibitor of CDK8 and its isoform CDK19

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