DCC5157 |
tipp-401 |
Dual PPA |
|
DCC5158 |
tipp-703 |
hPPAR-pan agonist |
|
DCC5159 |
Tiracizine Hydrochloride |
Anti-arrhythmia agent |
|
DCC5160 |
Tl13-117 |
Novel AC220-based FLT3 degrader |
|
DCC5161 |
Tl13-149 |
Novel AC220-based FLT3 degrader |
|
DCC5162 |
Tli3-12 |
The first small molecule degrader, inducing anaplastic lymphoma kinase (ALK) degradation, including in non-small-cell lung cancer (NSCLC), anaplastic large-cell lymphoma (ALCL), and neuroblastoma (NB) cell lines |
|
DCC5163 |
Tli3-i12 |
The first small molecule degrader, inducing anaplastic lymphoma kinase (ALK) degradation, including in non-small-cell lung cancer (NSCLC), anaplastic large-cell lymphoma (ALCL), and neuroblastoma (NB) cell lines |
|
DCC5164 |
Tlk19781 |
Novel Insulin Receptor Modulator |
|
DCC5165 |
tlr4-in-c35 |
Novel Toll-Like Receptor 4 (TLR4) Inhibitor |
|
DCC5166 |
Tlr7/8-in-cmpd2 |
Novel potent and selective dual TLR7/8 inhibitor |
|
DCC5167 |
Tlr8-in-5 |
Novel toll-like receptor 8 (TLR8) inhibitor, potently and selectively reducing TLR8-mediated signaling |
|
DCC5168 |
Tls-in-5 |
The first small molecule inhibitor of translesion synthesis (TLS) that target Rev1-CT |
|
DCC5169 |
Tm2-119 |
Potent histone methyltransferase inhibitor with rapid antimalarial activity against all blood stage forms in Plasmodium falciparum |
|
DCC5170 |
Tm-233 |
Novel inhibitor of both JAK/STAT and proteasome activities, inducing cell death in myeloma cells |
|
DCC5171 |
Tm5001 |
Novel inhibitor of plasminogen activator inhibitor-1 (PAI-1) |
|
DCC5172 |
Tma-230 |
Penem beta-lactam antibiotic |
|
DCC5173 |
Tmc-310911 |
Novel protease inhibitor (PI) against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to generate resistance, also showing antiviral avtivity as a potential treatment for COVID-19 caused by SARS-CoV-2 |
|
DCC5174 |
Tm-p4-thal |
Dual Inhibitor of SIRT2 Deacetylase and Defatty-Acylase Activities |
|
DCC5175 |
Tmp-b3a |
Novel degrader of E. coli DHFR (eDHFR), as well as eDHFR-EGFP fusion proteins, demonstrating that degradation does not require covalent attachment of the tag to the target protein |
|
DCC5176 |
Tmp-nvoc-halo |
Novel caged protein labeling agent |
|
DCC5177 |
Tmppaa |
Allosteric agonist and positive allosteric modulator (PAM) of 5-HT3 receptor |
|
DCC5178 |
Tmq0153 |
Novel activator of necrostatin-1 sensitive necroptotic cell death, triggering apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia |
|
DCC5179 |
Tnfalpha-in-4e |
Novel potent inhibitor of TNF-α |
|
DCC5180 |
Tnfalpha-in-5783168 |
Novel inhibitor of tumor necrosis factor-α (TNF-α) |
|
DCC5181 |
Tnk-6123 |
Emivirine analog with improved activity against drug-resistant HIV mutants |
|
DCC5182 |
Tnk-651 |
Novel non-nucleoside reverse transcriptase inhibitor of HIV-1 |
|
DCC5183 |
Tnks/usp25-in-c44 |
Novel selective inhibitor of TNKS-USP25 interaction, effectively reducing prostate cancer cell proliferation and tumor growth |
|
DCC5184 |
Tnks2-in-5 |
Novel highly potent and selective TNKS2 inhibitor with antiproliferative effects in a colorectal cancer cell line (DLD-1) where the Wnt pathway is constitutively activated |
|
DCC5185 |
Tnks-in-1 |
Highly potent and selective tankyrase inhibitor |
|
DCC5186 |
Tnks-in-21 |
Novel potent and selective tankyrase (TNKS) inhibitor |
|