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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC5277 Bll5 Maleate First-in-class selective PRMT5 inhibitor, blocking EBV-driven B lymphocyte transformation and survival while leaving normal B cells unaffected
DCC5278 Tyr(po(nme2)2 Stable analog of phosphotyrosine (pTyr)
DCC5279 Tyrosinase Inhibitor Thio-2 Novel competitive inhibitor of tyrosinase enzyme
DCC5280 U-101958 Maleate [224170-09-6] Potent and selective dopamine D4 receptor antagonist
DCC5281 Ua62784 Novel potent inhibitor of microtubule polymerization, binding directly to tubulin α/β heterodimers via the colchicine-binding site, perturbing mitotic spindles, delaying cells in mitosis and promotes apoptosis
DCC5282 Uawj172 Novel potent and broad-spectrum antiviral agent against multiple strains of EV-D68, EV-A71, and CVB3, targeting the viral protein 2C
DCC5283 Ubp512 Selective modulator of NMDA_receptor>NMDA receptors, potentiates responses at GluN1/GluN2A
DCC5284 Ubp618 Novel pan-inhibitor of GluN1/GluN2 receptors
DCC5285 Ubp646 Novel pan potentiator of GluN1/GluN2 receptors
DCC5286 Ubp684 Novel NMDAR positive allosteric modulator (PAM), robustly potentiating responses at all GluN1/GluN2 subtypes and at neuronal NMDARs
DCC5287 Ubtr008295a Novel Antagonist of the USP5 Zinc Finger Ubiquitin-Binding Domain (USP5 ZnF-UBD)
DCC5288 Ucb-11056 Modulator of cyclic AMP generation, amplifing induced cyclic AMP formation in rat brain tissue; Nootropic
DCC5289 ucb30889 Potent ligand of synaptic vesicle protein 2A (SV2A)
DCC5290 Ucb-6786 Novel inhibitor of TNF signalling by stabilising an asymmetric form of the trimer, displaying a concentration-dependent response curve and selectivity over the TNFR1 extracellular domain and control proteins
DCC5291 Ucb-6876 Novel inhibitor of TNF signalling by stabilising an asymmetric form of the trimer, displaying a concentration-dependent response curve and selectivity over the TNFR1 extracellular domain and control proteins
DCC5292 Ucb-fcrn-303 Novel allosteric modulator of neonatal Fc receptor (FcRn), binding to the extracellular domain of FcRn
DCC5293 uc-ddc-918013 Selective competitive inhibitor of ATX-mediated hydrolysis of the lysophospholipase substrate FS-3
DCC5294 uc-ddc-931126 Selective competitive inhibitor of ATX-mediated hydrolysis of the lysophospholipase substrate FS-3
DCC5295 uc-ddc-966791 Competitive dual inhibitor of the hydrolysis FS-3 and the phosphodiesterase substrate p-nitrophenyl thymidine 5'-monophosphate
DCC5297 Uck2-in-135546734 Novel non-competitive UCK2 inhibitor, suppressing nucleoside salvage in cells both in the presence and absence of DHODH inhibitors
DCC5298 Uck2-in-135546812 Novel non-competitive UCK2 inhibitor, suppressing nucleoside salvage in cells both in the presence and absence of DHODH inhibitors
DCC5299 Uck2-in-20874830 Novel non-competitive UCK2 inhibitor, suppressing nucleoside salvage in cells both in the presence and absence of DHODH inhibitors
DCC5300 ucl-1972 Histamine H3 Receptor Antagonist in Treatments of Cognition Disorders
DCC5301 Ucl-2190 Hydrogen Maleate The first potent nonimidazole H3 receptor antagonist (pKi=8.40)
DCC5302 Ucm-05194 Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), Showing Efficacy in Neuropathic Pain Amelioration
DCC5303 Ucm-1336 Novel potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor, improving survival in Ras-driven acute myeloid leukemia
DCC5304 Ucm710 Dual inhibitor of fatty acid amide hydrolase (FAAH) and α/β hydrolase domain 6 (ABHD6)
DCC5305 Ucn-02 Stereoisomer of UCN-01, inhibiting protein kinase C with a slightly reduced potency than UCN-01
DCC5306 Ucp1172 Novel dual inhibitor of dihydrofolate reductase (DHFR) and its functional analog, Rv2671
DCC5307 Ucph-102f Fluorescent excitatory amino acid transporter subtype 1 (EAAT1) selective inhibitor

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