| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC22611 | N6-[2-(4-Aminophenyl)ethyl]adenosine | A non-selective agonist of Adenosine A3 receptor. |
|
| DC22619 | Rotigotine Featured | A non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM). |
|
| DC22609 | rac-Rotigotine hydrochloride | A non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM). |
|
| DC22662 | Carteolol | A non-selective beta blocker used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.. |
|
| DC23203 | E4CPG Featured | A non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist.. |
|
| DC11763 | ABP 1 | A nonselective inhibitor of UBL protein-activating E1 enzymes that forms covalent adducts with UBL proteins SUMO1, ubiquitin, Nedd8, ISG15, and GABARAP in the presence of ATP and E1 enzymes in vitro. |
|
| DC24159 | (R)-Flurbiprofen | A non-steroidal anti-inflammatory drug (NSAID). |
|
| DC22769 | Droloxifene | A nonsteroidal selective estrogen receptor modulator (SERM) that shows 10- to 60-fold increased affinity for the estrogen receptor compared with Tamoxifen. |
|
| DC21706 | STX3451 | A non-steroidal sulphamate analogue of 2-methoxyoestradiol (2ME2) and microtubule disruptor, shows anti-proliferative activity against NCI 60 cell lines with mean GI50 of 50 nM. |
|
| DC11919 | Arimoclomol Featured | A nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response. |
|
| DC11920 | Arimoclomol maleate Featured | A nontoxic, orally active heat shock protein (HSP) coinducer and potentiator of the heat shock response. |
|
| DC24034 | Coluracetam | A nootropic agent that enhances high-affinity choline uptake. |
|
| DC21342 | MPT0L145 | A nove potent, dual FGFR and PIK3C3 inhibitor with Kd of 0.53 nM for PIK3C3. |
|
| DC20550 | SHP2 inhibitor 2 | A nove potent, selective and reversible SHP2 inhibitor with Ki of 0.51 uM. |
|
| DC11523 | Landipirdine | A novel 5-HT receptor antagonist for the treatment of Parkinson's disease.. |
|
| DC11793 | UMB-32 | A novel a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM. |
|
| DC23493 | Ladarixin | A novel allosteric, noncompetitive dual CXCR1/2 inhibitor that inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8 in vitro with IC50 of 0.7 nM. |
|
| DC23467 | Ladarixin sodium | A novel allosteric, noncompetitive dual CXCR1/2 inhibitor that inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8 in vitro with IC50 of 0.7 nM. |
|
| DC20706 | AVN-211 | A novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM. |
|
| DC22565 | K-Ras G12C-IN-3 | A novel and irreversible inhibitor of mutant K-ras G12C.. |
|
| DC22572 | K-Ras G12C-IN-2 | A novel and irreversible inhibitor of mutant K-ras G12C.. |
|
| DC22573 | K-Ras G12C-IN-1 | A novel and irreversible inhibitor of mutant K-ras G12C.. |
|
| DC22587 | FT011 Featured | FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis. |
|
| DC11888 | Arfolitixorin | A novel antifolate modulator compound.. |
|
| DC22391 | Olorofim(F-901318) | Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp. |
|
| DC11998 | IND-114338 | A novel antiprion compound with EC50 of 68 nM, significantly increases monoglycosylated/diglycosylated PrPSc.. |
|
| DC11534 | Sudoterb Featured | A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL.. |
|
| DC11535 | Sudoterb dihydrchloride | A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL.. |
|
| DC11663 | GS-5759 | A novel bifunctional PDE4 inhibitor (IC50=5 nM) and long acting β2-adrenoceptor agonist (EC50=8 nM). |
|
| DC11997 | IND125 | A novel brain penetrant antiprion compound with EC50 of 57 nM, prevents both PrP(Sc) accumulation and astrocytic gliosis in the cerebrum. |
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