Rotigotine| CAS 99755-59-6|DC Chemicals

Cas No.:	99755-59-6
Chemical Name:	1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (6S)-
SMILES:	CCCN([C@H]1CCC2C(=CC=CC=2C1)O)CCC1=CC=CS1
Formula:	C₁₉H₂₅NOs
M.Wt:	315.4729
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM); has 10-fold selectivity for the D3 receptor over the D2, D4, and D5 receptors and 100-fold selectivity for the D3 receptor over the D1 receptor; behaves as a full agonist of D1, D2, and D3 with similar potencies (EC50) in functional assay; also demonstrates significant affinity at α-adrenergic (α2B, Ki=27 nM) and serotonin receptors (5-HT1A Ki=30 nM); significantly attenuates MPTP-induced acute cell degeneration in mouse model.Parkinson's DiseaseApproved

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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