Cat. No. | Product name | CAS No. |
DC22426 |
Bromocriptine
Bromocriptine (2-Bromoergocriptine. |
25614-03-3 |
DC23899 |
Bromocriptine mesylate
Featured
Bromocriptine (CB-154) is a dopamine D2 receptor agonist (Ki=3 nM) and and various serotonin receptors, also inhibits the release of glutamate by reversing the glutamate GLT1 transporter. |
22260-51-1 |
DC12633 |
Bromotriazine
Bromotriazine (BTZ) is a covalent probe against bromodomain containing proteins with selectively targeting non-catalytic, highly conserved amino acid residues.. |
|
DC23385 |
BRPF1B TRIM24-IN-34
BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively. |
1242907-48-7 |
DC10913 |
Brusatol
Brusatol (NSC 172924, (+)-Brusatol) is a quassinoid extracted from Brucea Esters, can inhibit HIF-1 signaling pathway, also is a potent Nrf2 inhibitor. |
14907-98-3 |
DC11038 |
Bryostatin 1
Featured
Bryostatin 1 (NSC 339555) is a macrocyclic lactone derived from a marine invertebrate, fuctions as an activator of PKC with high binding affinity (Ki=1.35 nM). |
83314-01-6 |
DC10954 |
BS148
BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1. |
2162116-09-6 |
DC8517 |
BS194
Featured
BS-194 is a selective and potent CDK inhibitor, which inhibits CDK2, CDK1, CDK5, CDK7, and CDK9 with IC50 values of 3, 30, 30, 250, and 90 nM respectively. |
1092443-55-4 |
DC7378 |
BSI-201
BSI-201 (Iniparib; NSC-746045) is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC). |
160003-66-7 |
DC26026 |
Btk inhibitor 2
Btk inhibitor 2 is a Bruton's tyrosine kinase (BTK) inhibitor extracted from patent US 20170224688 A1. |
1558036-85-3 |
DC12432 |
BTK inhibitor 4b
BTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively. |
1646608-10-7 |
DC11065 |
BTK PROTAC 10
BTK PROTAC 10 is a novel potent PROTAC for BTK with DC50 of 1.1 nM in cultured Ramos cells. |
|
DC11064 |
BTK PROTAC 9
BTK PROTAC 9 is a novel potent PROTAC for BTK with DC50 of 5.9 nM in cultured Ramos cells, requires simultaneous engagement of BTK and CRBN to effectively degrade BTK. |
|
DC11431 |
BTK-030
BTK-030 is a novel BTK inhibitor. |
2241732-30-7 |
DC23870 |
BTK-IN-23
BTK-IN-23 is a highly potent and selective Btk inhibitor with IC50 of 3 nM. |
1227206-13-4 |
DC23413 |
BTRX335140
Featured
BTRX-335140 (CYM-53093, BTRX335140, CYM53093) is a potent, selective, orally active κ opioid receptor (KOR) antagonist with IC50 of 0.8 nM. |
2244614-14-8 |
DC12456 |
BTT-266
Featured
BTT-266 (BTT266) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction, directly binds to CaVβ3 with Kd of 3.6 uM. |
2413939-89-4 |
DC12457 |
BTT-369
BTT-369 (BTT369) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction with Ki of 2.0 uM in FP assays. |
|
DC11252 |
BTX161
BTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53, while stabilizing the p53 antagonist MDM2. |
2052301-24-1 |
DC23703 |
BTYNB
Featured
BTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA with IC50 of 5 uM. |
304456-62-0 |
DCAPI1392 |
BTZ043 racemate
Featured
BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis. |
957217-65-1 |
DC22041 |
BTZO-1
Featured
BTZO-1 is a cardioprotective agent and Macrophage migration inhibitory factor (MIF) activator, binds to MIF with Kd of 68.6 nM, regulates ARE-mediated gene expression. |
99420-15-2 |