| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21025 | FR900098 sodium salt Featured | FR 900098 is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively.. |
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| DC12242 | FR194738 | FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. |
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| DC12398 | FR58P1a | FR58P1a is a mitochondrial metabolism-affecting compound that uncouples OXPHOS through a protonophoric mechanism, selectively inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway. |
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| DC23729 | FR-901464 Featured | FR-901464 is a potent antitumor natural product that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, inhibits cell cycle progression at G1 and G2/M phases.. |
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| DC10307 | Framycetin | Framycetin (Fradiomycin B; Neomycin B) is an aminoglycoside antibiotic. It inhibits hammerhead ribozyme with a Ki of 13.5 μM. |
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| DC8631 | Framycetin sulphate | Framycetin sulphate |
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| DC9887 | FRAX1036 Featured | FRAX1036 is a novel ATP-competitive small molecule inhibitor of group I p21-activated Kinases (PAKs). |
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| DC8003 | FRAX-486 Featured | FRAX486 is a selective inhibitor of group I PAKs with IC50s of 8.25/39.5, /55.3 nM for PAK1/PAK2/PAK3 respectivelt; less potent for PAK4(IC50=779 nM). |
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| DC9344 | Frentizole | Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction. |
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| DC20208 | Frovatriptan Succinate | Frovatriptan Succinate is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors. |
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| DC21026 | FSC 231 | FSC 231 (FSC231) is the first, cell-permeable small-molecule inhibitor of PICK1 PDZ domain with Kd of 10.1 uM. |
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| DC23388 | FT-001 | FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1. |
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| DC11554 | FT-671 Featured | FT-671 is a novel potent, specific, non-covalent USP7 inhibitor with Kd of 65 nM (USP7 catalytic domain). |
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| DC22096 | FT895 | FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM). |
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| DC11029 | FTBMT Featured | FTBMT is a novel selective GPR52 agonist of GPR52, increases intracellular cAMP levels in CHO cells expressing human, mouse, or rat GPR52, with pEC50 of 7.03, 6.85, and 6.87M, respectively. |
|
| DC8421 | FTI 277 HCl Featured | FTI 277 HCl is the methyl ester of FTI 277, which is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. |
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| DC12537 | FtsZ inhibitor C109 | FtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2 uM. |
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| DC3154 | Fingolimod HCl（FTY-720） Featured | FTY720 (Fingolimod, Gilenya) is a S1P antagonist with IC50 of 0.033 nM. |
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| DC12362 | Fuchsine base monohydrochloride | Fuchsine base (monohydrochloride) is a magenta dye, which is certified for use for acid-fast staining with carbol-fuchsin. |
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| DC21027 | Fumosorinone | Fumosorinone is a novel potent, selective protein tyrosine phosphatase SHP2 inhibitor with IC50 of 6.31 uM. |
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| DC11235 | Furamidine dihydrochloride Featured | Furamidine dihydrochloride (NSC 305831) tyrosyl-DNA phosphodiesterase (Tdp1), also is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with IC50 of 9.4 uM. |
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| DC10240 | Fusidate Sodium | Fusidate Sodium is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections. |
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| DC21792 | FV-100 | FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.. |
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| DC21031 | FzM1.8 | FzM1.8 is a small molecule, allosteric agonist of the Frizzled receptor Fzd4 with pEC50 of 6.4, potentiates β-catenin pathway in the absence of any WNT ligand. |
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| DC21032 | G 0507 | G 0507 is a novel inhibitor of the bacterial LolCDE ABC transporter, binds to LolCDE and stimulates its ATPase activity. |
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| DC21034 | G 573 | G 573 is a potent and selective, allosteric inhibitor of MEK with Ki of 0.3 nM. |
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| DC11449 | G0775 | G0775 is a Synethetic analogs of arylomycins. |
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| DC24027 | STING Agonist-1(G-10) Featured | G10 (STING Agonist 1) is a novel human-specific STING agonist. |
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| DC12300 | G3-C12 TFA | G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. |
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| DC22548 | G-5555 | G-5555 is a potent and selective PAK1 inhibitor (Ki=3.7 nM). |
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