| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC12438 | G6PD activator AG1 Featured | G6PD activator AG1 (AG1) is a specific, small molecule that increases the activity of the wild-type, Canton mutant (R459L, EC50=3 uM) and several other common G6PD mutants; displays no effect on the dimerization or activity of several other NAD- or NADP+-dependent dimeric or tetrameric enzymes, including 6PGD, GAPDH, ALDH2, and ALDH3A1; attenuates ROS-induced pericardial edema in a G6PD-dependent manner in zebrafish, reduces hemolysis of human erythrocytes |
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| DC11776 | G-744 | G-744 is a highly potent, selective inhibitor of BTK with biochemical Ki of 1.28 nM. |
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| DC21035 | G907 | G907 is a potent, selective small-molecule antagonist of ATP-binding cassette (ABC) transporter MsbA with IC50 of 18 nM. |
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| DC21036 | E-72 | G9a inhibitor E72 (E-72) is a potent inhibitor of histone H3K9 methyltransferases G9a and G9a-like protein (GLP) with Kd of 136 nM and 164 nM, shows selectivity over the related H3K9 methyltransferase Suv39H2. |
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| DC9381 | Gabapentin (hydrochloride) | Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. |
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| DC11053 | GAK inhibitor 49 Featured | GAK inhibitor 49 is a potent, selective, ATP-competitive inhibitor of cyclin G-associated kinase (GAK, cell IC50=56 nM) with favourable NAK family selectivity (AAK1, STK16, BMP2K). |
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| DC12228 | Galactose 1-phosphate | Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars. |
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| DC12305 | Galactose 1-phosphate Potassium salt | Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sugars |
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| DC21038 | Galvestine-1 | Galvestine-1 is a small molecule MGDG (monogalactosyldiacylglycerol) synthase inhibitor with IC50 of 10 uM by competing with diacylglycerol binding. |
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| DC11071 | Gambogenic acid | Gambogenic acid (GNA) is a polyprenylated xanthone isolated from gamboge, shows potent antitumor activity and can effectively inhibit the survival and proliferation of cancer cells. |
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| DC12090 | Gamitrinib TPP | Gamitrinib TPP is a GA mitochondrial matrix inhibitor. |
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| DC9640 | gamma-secretase modulator 3 | gamma-secretase modulator 3 is a gamma-secretase modulator. |
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| DC21197 | Ganaplacide Featured | Ganaplacide (KAF156, GNF-156) is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains. |
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| DC9453 | GANT 58 | GANT 58 is a novel and potent Gli antagonist that inhibits GLI1-induced transcription (IC50 = 5 uM). |
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| DC20388 | GAPDS Featured | GAPDS is a small molecule that targets the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH). |
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| DC23398 | Garcinol | Garcinol (Camboginol) is a potent, natural inhibitor of histone acetyltransferases (HATs) p300 (IC50=7 uM) and PCAF (IC50=5 uM) both in vitro and in vivo. |
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| DC8929 | Garenoxacin | Garenoxacin is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections. |
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| DC8893 | Garenoxacin Mesylate hydrate | Garenoxacin mesylate hydrate is a novel oral des-fluoro(6) quinolone with potent antimicrobial activity, against common respiratory pathogens, including resistant strains. |
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| DC11122 | GAT-100 | GAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM, does not exhibit inverse agonism. |
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| DC11119 | GAT-211 | GAT-211 (GAT211) is a selective cannabinoid 1 receptor (CB1R) positive allosteric modulator with pKb of 7.26, Arrestin2 EC50 of 775 nM. |
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| DC11741 | GB-110 | GB-110 is a potent, non-peptidic agonist of PAR2 that selectively induces PAR2-mediated intracellular Ca(2+) release in HT29 cells with EC50 of 0.28 uM. |
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| DC22098 | GB1107 | GB1107 (GB-1107, GB 1107) is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with Kd of 37 nM (human Galectin-3). |
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| DC21040 | GB-83 | GB-83 is a selective, reversible PAR2 (Protease-activated receptor 2) antagonist with IC50 of 2 uM. |
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| DC11740 | GB-88 | GB-88 is a selective, orally available PAR2 antagonist that inhibits PAR2 activated Ca(2+) release with IC50 of 2 uM. |
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| DC10153 | GDC-0077 Featured | GDC-0077 is an orally available PI3K inhibitor with potential antineoplastic activity. GDC-0077 is extracted from patent WO 2017001645 A1, formula I. |
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| DC10035 | GDC-0326 | GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). |
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| DC8216 | GDC-0349 | GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM; >700-fold selectivity over PI3Kα and other 266 kinases. |
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| DC8519 | GDC046 Featured | GDC046 is a potent lead analog with good kinase selectivity, physicochemical properties, and pharmacokinetic profile. |
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| DC8000 | GDC-0623 Featured | GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP). |
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| DC9942 | GDC-0853(RG7845) Featured | GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. |
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