| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23614 | IQM-266(IQM 266;IQM266) | IQM-266 (IQM266) is a DREAM (Downstream Regulatory Element Antagonist Modulator) ligand (Kd=4.63 uM), inhibits the KV4.3/DREAM current in a concentration-, voltage-, and time-dependent-manner. |
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| DC21151 | IR415 | IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease. |
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| DC9491 | IRAK inhibitor 1 Featured | IRAK inhibitor 1 is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. |
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| DC9492 | IRAK inhibitor 2 | IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor . |
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| DC9493 | IRAK inhibitor 6 | IRAK inhibitor 6 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor . |
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| DC23594 | Irampanel | Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
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| DC23566 | Irampanel hydrochloride | Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
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| DC22411 | Irdabisant hydrochloride | Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
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| DC22419 | Irdabisant | Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
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| DC20422 | IRE1α-IN-3 | IRE1α-IN-3 is a novel, potent IRE1α RNase inhibitor with EC50 of 0.82 uM. |
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| DC4180 | Irinotecan Hydrochloride Featured | Irinotecan hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. |
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| DC4153 | Irinotecan hydrochloride trihydrate | Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. |
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| DC22097 | IS-741 | IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2).. |
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| DC10340 | ISA-2011B | ISA-2011B is a PIP5Kα inhibitor with promising anticancer effects . |
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| DC23284 | ISA27 | ISA27 is a novel small molecule that blocks p53-MDM2 interaction and induces apoptosis both in vitro and in vivo. |
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| DC9891 | Isatin | Isatin is an endogenous MAO inhibitor. |
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| DC7609 | Isatoribine | Isatoribine is a selective agonist of TLR7 |
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| DC8120 | Isavuconazole | Isavuconazole(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557, exhibits MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata. |
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| DC11341 | Isavuconazonium (sulfate) | Isavuconazonium is a water-soluble prodrug form of the azole antifungal isavuconazole (ISA). |
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| DC8427 | Isepamicin Sulphate | Isepamicin Sulphate is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit. |
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| DC21153 | ISO-66 | ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM. |
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| DC22118 | ISO-92 | ISO-92 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity with IC50 of 0.55 uM.. |
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| DC12146 | Isoastragaloside IV | Isoastragaloside IV is a triterpene oligoglycoside isolated from Astragali Radix. |
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| DC21133 | Isobutyl-deoxynyboquinone | Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner. |
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| DC20010 | Isocarboxazid | Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase, with an IC50 of 4.8 μM for rat brain monoamine oxidase in vitro. |
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| DC12071 | Isocryptotanshinone | Isocryptotanshinone is a potent signal transducer and activator of transcription 3 (STAT3) and protein tyrosine phosphatase 1B PTP1B inhibitor, with an IC50 of 56.1 μM for PTP1B. |
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| DC23768 | Isoginkgetin | Isoginkgetin (Iso-ginkgetin. |
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| DC22585 | Isomangiferin | Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel. |
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| DC21154 | Isomigrastatin | Isomigrastatin (iso-Migrastatin) is an analogue of migrastatin that shows potent antiproliferative effect on tumor cell lines and selectively inhibits translation. |
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| DC20215 | Isonicotinic acid; Isoniazid, 4-pyridinecarboxylic acid, p-pyridinecarboxylic acid, 4-Picolinic acid | Isonicotinic acid is a metabolite of isoniazid. It is an isomer of nicotinic acid. |
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