| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21138 | Inflachromene Featured | Inflachromene (ICM) is a microglial inhibitor with anti-inflammatory effects, directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. |
|
| DC9651 | Ingenol 3-angelate Featured | Ingenol 3-Angelate is a PKC(protein kinase C)activator; anti-cancer drug and an active ingredient in Euphorbia peplus. |
|
| DC9653 | Ingenol 5,20-Acetonide | Ingenol 5,20-Acetonide (CAS 77573-43-4) |
|
| DC9654 | Ingenol 5,20-Acetonide-3-O-angelate | Ingenol 5,20-Acetonide-3-O-angelate (CAS 87980-68-5) |
|
| DC9652 | Ingenol-3,4:5,20-diacetonide | Ingenol-3,4:5,20-diacetonide (CAS 77573-44-5) |
|
| DC22212 | RNF5 INHIBITOR INH-02 Featured | inh-02 (RNF5 inhibitor inh-02) is a novel small molecule inhibitor of E3 ubiquitin ligase RNF5/RMA1. |
|
| DC7640 | INH1 | INH1 is a cell-permeable Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interaction. |
|
| DC12310 | INH154 | INH154 is a highly potent inhibitor for Nek2 and Hec1 binding (INH), with IC50s of 200 nM and 120 nM for INH in Hela and MB468 cells. |
|
| DC21704 | Inh2-B1 | Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain. |
|
| DC7487 | Pyroxamide Featured | Inhibitor of histone deacetylase (HDAC); potently inhibits affinity purified HDAC1. Also inhibits the growth of tumor cells in vitro and in vivo. Induces p21/WAF1 expression in tumor cells. |
|
| DC8132 | TAPI-0 (TNF-α processing inhibitor-0) | Inhibits TNF-α processing. Also a general matrix metalloprotease and TACE inhibitor. |
|
| DC7171 | INK-128(Sapanisertib) Featured | INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less potent to class I PI3K isoforms. |
|
| DC7873 | INK-055 (PI3Kγ inhibitor 1) | INK055 is a dual PI3Kg/d inhibitor. |
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| DC23238 | INO-1001 | INO-1001 is a potent, selective poly(ADP-ribose) polymerase (PARP) with IC50 of <50 nM in CHO cells. |
|
| DC20417 | iNOS inhibitor 12 | iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS.. |
|
| DC12101 | Insulin levels modulator | Insulin levels modulator could be used to treat diabetes. |
|
| DC22513 | INT-767 | INT-767 is a potent, selective, dual farnesoid X receptor (FXR) and TGR5 agonist with EC50 of 30 and 630 nM, respectively. |
|
| DC12106 | Interferon receptor agonist | Interferon receptor agonist is an interferonm (IFN) receptor agonist. |
|
| DC11494 | INX-08189 | INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
|
| DC12160 | Iodipamide (Adipiodone) | Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging. |
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| DC20420 | Ionomycin calcium salt | Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. |
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| DC20419 | Ionomycin | Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus. |
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| DC9564 | Iopamidol | Iopamidol is a nonionic, low-osmolar iodinated contrast agent. |
|
| DC7172 | IOWH-032 | iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays. |
|
| DC21756 | IP6K1 inhibitor TNP Featured | IP6K1 inhibitor TNP is a potent, selective inositol hexakisphosphate kinase IP6K with IC50 of 0.47 uM (IP6K1), does not inhibit either human or yeast Vip/PPIP5K. |
|
| DC9575 | IPA-3 | IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6). |
|
| DC12599 | IPI-9119 | IPI-9119 (IPI9119) is a potent, selective, and irreversible inhibitor of fatty acid synthase (FASN) with IC50 of 0.3 nM in biochemical assays. |
|
| DC20667 | Ipidacrine hydrochloride hydrate | Ipidacrine hydrochloride hydrate is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
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| DC20666 | Ipidacrine hydrochloride | Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
|
| DCAPI1573 | Ipragliflozin (ASP1941) Featured | Ipragliflozin (ASP1941) is a Novel Selective Sodium-Dependent Glucose Co-Transporter 2 Inhibitor, on Urinary Glucose Excretion in Healthy Subjects |
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