| DC20417 |
iNOS inhibitor 12 |
iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS.. |
|
| DC12101 |
Insulin levels modulator |
Insulin levels modulator could be used to treat diabetes. |
|
| DC22513 |
INT-767 |
INT-767 is a potent, selective, dual farnesoid X receptor (FXR) and TGR5 agonist with EC50 of 30 and 630 nM, respectively. |
|
| DC12106 |
Interferon receptor agonist |
Interferon receptor agonist is an interferonm (IFN) receptor agonist. |
|
| DC11494 |
INX-08189 |
INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
|
| DC12160 |
Iodipamide (Adipiodone) |
Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging. |
|
| DC20420 |
Ionomycin calcium salt |
Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. |
|
| DC20419 |
Ionomycin |
Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus. |
|
| DC9564 |
Iopamidol |
Iopamidol is a nonionic, low-osmolar iodinated contrast agent.
|
|
| DC7172 |
IOWH-032 |
iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays. |
|
| DC21756 |
IP6K1 inhibitor TNP
Featured
|
IP6K1 inhibitor TNP is a potent, selective inositol hexakisphosphate kinase IP6K with IC50 of 0.47 uM (IP6K1), does not inhibit either human or yeast Vip/PPIP5K. |
|
| DC9575 |
IPA-3 |
IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).
|
|
| DC12599 |
IPI-9119 |
IPI-9119 (IPI9119) is a potent, selective, and irreversible inhibitor of fatty acid synthase (FASN) with IC50 of 0.3 nM in biochemical assays. |
|
| DC20667 |
Ipidacrine hydrochloride hydrate |
Ipidacrine hydrochloride hydrate is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
|
| DC20666 |
Ipidacrine hydrochloride |
Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
|
| DCAPI1573 |
Ipragliflozin (ASP1941)
Featured
|
Ipragliflozin (ASP1941) is a Novel Selective Sodium-Dependent Glucose Co-Transporter 2 Inhibitor, on Urinary Glucose Excretion in Healthy Subjects |
|
| DC23614 |
IQM-266(IQM 266;IQM266) |
IQM-266 (IQM266) is a DREAM (Downstream Regulatory Element Antagonist Modulator) ligand (Kd=4.63 uM), inhibits the KV4.3/DREAM current in a concentration-, voltage-, and time-dependent-manner. |
|
| DC21151 |
IR415 |
IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease. |
|
| DC9491 |
IRAK inhibitor 1
Featured
|
IRAK inhibitor 1 is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. |
|
| DC9492 |
IRAK inhibitor 2 |
IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor . |
|
| DC9493 |
IRAK inhibitor 6 |
IRAK inhibitor 6 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor . |
|
| DC23594 |
Irampanel |
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
|
| DC23566 |
Irampanel hydrochloride |
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
|
| DC22411 |
Irdabisant hydrochloride |
Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
|
| DC22419 |
Irdabisant |
Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
|
| DC20422 |
IRE1α-IN-3 |
IRE1α-IN-3 is a novel, potent IRE1α RNase inhibitor with EC50 of 0.82 uM. |
|
| DC4180 |
Irinotecan Hydrochloride
Featured
|
Irinotecan hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. |
|
| DC4153 |
Irinotecan hydrochloride trihydrate |
Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. |
|
| DC22097 |
IS-741 |
IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2).. |
|
| DC10340 |
ISA-2011B |
ISA-2011B is a PIP5Kα inhibitor with promising anticancer effects . |
|
