| DC22212 |
RNF5 INHIBITOR INH-02
Featured
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inh-02 (RNF5 inhibitor inh-02) is a novel small molecule inhibitor of E3 ubiquitin ligase RNF5/RMA1. |
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| DC7640 |
INH1 |
INH1 is a cell-permeable Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interaction. |
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| DC12310 |
INH154 |
INH154 is a highly potent inhibitor for Nek2 and Hec1 binding (INH), with IC50s of 200 nM and 120 nM for INH in Hela and MB468 cells. |
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| DC21704 |
Inh2-B1 |
Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain. |
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| DC7487 |
Pyroxamide
Featured
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Inhibitor of histone deacetylase (HDAC); potently inhibits affinity purified HDAC1. Also inhibits the growth of tumor cells in vitro and in vivo. Induces p21/WAF1 expression in tumor cells. |
|
| DC8132 |
TAPI-0 (TNF-α processing inhibitor-0) |
Inhibits TNF-α processing. Also a general matrix metalloprotease and TACE inhibitor. |
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| DC7171 |
INK-128(Sapanisertib)
Featured
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INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less potent to class I PI3K isoforms. |
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| DC7873 |
INK-055 (PI3Kγ inhibitor 1) |
INK055 is a dual PI3Kg/d inhibitor. |
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| DC23238 |
INO-1001 |
INO-1001 is a potent, selective poly(ADP-ribose) polymerase (PARP) with IC50 of <50 nM in CHO cells. |
|
| DC20417 |
iNOS inhibitor 12 |
iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS.. |
|
| DC12101 |
Insulin levels modulator |
Insulin levels modulator could be used to treat diabetes. |
|
| DC22513 |
INT-767 |
INT-767 is a potent, selective, dual farnesoid X receptor (FXR) and TGR5 agonist with EC50 of 30 and 630 nM, respectively. |
|
| DC12106 |
Interferon receptor agonist |
Interferon receptor agonist is an interferonm (IFN) receptor agonist. |
|
| DC11494 |
INX-08189 |
INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
|
| DC12160 |
Iodipamide (Adipiodone) |
Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging. |
|
| DC20420 |
Ionomycin calcium salt |
Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. |
|
| DC20419 |
Ionomycin |
Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus. |
|
| DC9564 |
Iopamidol |
Iopamidol is a nonionic, low-osmolar iodinated contrast agent.
|
|
| DC7172 |
IOWH-032 |
iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays. |
|
| DC21756 |
IP6K1 inhibitor TNP
Featured
|
IP6K1 inhibitor TNP is a potent, selective inositol hexakisphosphate kinase IP6K with IC50 of 0.47 uM (IP6K1), does not inhibit either human or yeast Vip/PPIP5K. |
|
| DC9575 |
IPA-3 |
IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).
|
|
| DC12599 |
IPI-9119 |
IPI-9119 (IPI9119) is a potent, selective, and irreversible inhibitor of fatty acid synthase (FASN) with IC50 of 0.3 nM in biochemical assays. |
|
| DC20667 |
Ipidacrine hydrochloride hydrate |
Ipidacrine hydrochloride hydrate is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
|
| DC20666 |
Ipidacrine hydrochloride |
Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
|
| DCAPI1573 |
Ipragliflozin (ASP1941)
Featured
|
Ipragliflozin (ASP1941) is a Novel Selective Sodium-Dependent Glucose Co-Transporter 2 Inhibitor, on Urinary Glucose Excretion in Healthy Subjects |
|
| DC23614 |
IQM-266(IQM 266;IQM266) |
IQM-266 (IQM266) is a DREAM (Downstream Regulatory Element Antagonist Modulator) ligand (Kd=4.63 uM), inhibits the KV4.3/DREAM current in a concentration-, voltage-, and time-dependent-manner. |
|
| DC21151 |
IR415 |
IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease. |
|
| DC9491 |
IRAK inhibitor 1
Featured
|
IRAK inhibitor 1 is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. |
|
| DC9492 |
IRAK inhibitor 2 |
IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor . |
|
| DC9493 |
IRAK inhibitor 6 |
IRAK inhibitor 6 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor . |
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