| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21311 | KT-195 | KT-195 is a potent and selective inhibitor of serine hydrolase ABHD6 (α/β-hydrolase domain-containing protein 6) with IC50 of 10 nM. |
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| DC21207 | KT-5720 | KT-5720 is a highly specific PKA (cAMP-dependent protein kinase) inhibitor with Ki of 60 nM displays little to no activity for MLCK, cGPK, and PKC (Ki>2 uM). |
|
| DC23732 | KT-5823 Featured | KT-5823 is a potent, highly specific PKG (cGMP-dependent protein kinase) inhibitor with Ki of 0.234 uM, displays little to no activity for MLCK, cAPK, and PKC. |
|
| DC3113 | KU-0060648 Featured | KU 0060648 is a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM); with 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases. |
|
| DC3101 | Ku-0063794 | KU-0063794 is a potent and highly specific mTOR inhibitor for both mTORC1 and mTORC2 with IC50 ~10 nM. |
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| DC7447 | KU14R | KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines. |
|
| DC21208 | KuWal151 | KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively. |
|
| DC7449 | KW-2478 Featured | KW-2478 is a nonansamycin HSP90 inhibitor with IC50 of 3.8 nM. Phase 1/2 |
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| DC21211 | KX2-361 | KX2-361 (KX 02) is a potent, dual Src signaling/tubulin polymerization inhibitor that are under clinical evaluation.. |
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| DC21212 | KY-02061 | KY-02061 is a small-molecule inhibitor of Dishevelled-CXXC5 interaction with IC50 of 24 uM in vitro binding assay. |
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| DC21213 | KY-02327 | KY-02327 is an orally active, small molecule inhibitor of the Dishevelled (Dvl)-CXXC5 interaction with IC50 of 3.1 uM, a metabolically stabilized KY-02061 analog. |
|
| DC21214 | KY-04045 | KY-04045 is a novel PAK4 inhibitor with IC50 of 8.7 uM, a basic building block in designing novel imidazo[4,5-b]pyridine-based PAK4 inhibitors.. |
|
| DC22132 | KY-05009 Featured | KY-05009 (KY05009) is a potent, ATP-competitive inhibitor of Traf2- and Nck-interacting kinase (TNIK) with Ki of 100 nM. |
|
| DC9889 | Kynurenic acid | Kynurenic acid, a natural metabolite of tryptophan via the kynurenine pathway, is a broad-spectrum excitatory amino acid antagonist. |
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| DC12332 | KZR-504 | KZR-504 is a highly selective and orally active inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4.274 μM for LMP2 and LMP7, respectively. |
|
| DC21217 | L 873724 | L 873724 is a potent and selective non-basic cathepsin K inhibitor with IC50 of 0.2 nM, shows no significant potency against Cat B, L, and S (IC50= 5239, 264, and 178 nM). |
|
| DC2076 | L-165041 Featured | L-165041 is a potent PPARδ agonist (Ki = 6 nM). |
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| DC22070 | L-257 | L-257 (DDAH-1 inhibitor L-257) is a selective, competitive DDAH1 inhibitor with IC50 of <25 uM. |
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| DC22071 | L-291 | L-291 (DDAH-1 inhibitor L-291) is a selective, competitive DDAH1 inhibitor with IC50 of <25 uM. |
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| DC21215 | L-338192 | L-338192 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 29 uM in AlphaScreen assay. |
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| DC23595 | L-364373 | L-364373 (R-L3) is a stereospecific activator of cardiac slowly activating delayed rectifier K+ current (IKs) and KV7.1 (KCNQ1) channels. |
|
| DC20041 | L-5-Hydroxytryptophan (L-5-HTP; Oxitriptan) Featured | L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydr |
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| DC11377 | L-826,266 | L-826,266 is a potent and selective competitive antagonist of the prostaglandin E2 receptor subtype EP3 (Ki = 0.8 nM). |
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| DC9382 | Lacidipine | Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker. |
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| DC20850 | Lactimidomycin | Lactimidomycin is a glutarimide antibiotic that has antifungal, antiviral and anti-cancer properties, acting as a direct inhibitor of protein translation in ribosomes. |
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| DC21218 | LAF389 | LAF389 is a potent methionine aminopeptidase (MetAP) inhibitor with IC50 of 800 nM for MetAP-2, inhibits both MetAp1 and 2, potently inhibits HUVEC proliferation with IC50 of 20 nM. |
|
| DC1108 | Laninamivir (CS-8958) Featured | Laninamivir (CS-8958) is a neuraminidase inhibitor which is being researched for the treatment and prophylaxis of Influenzavirus A and Influenzavirus B. |
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| DC23824 | Lanperisone | Lanperisone (NK 433) is a centrally acting muscle relaxant that selectively kills of K-ras mutant cancer cells in a cell cycle-independent fashion. |
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| DC23502 | L-AP4 Featured | L-AP4 is a selective group III metabotropic glutamate receptor agonist.. |
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| DC9433 | Lapatinib (ditosylate) | Lapatinib ditosylate(GW-572016 ditosylate) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively. |
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