| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC12472 | LAS195319 | LAS195319 (LAS-195319) is a potent, selective, inhaled PI3Kδ inhibitor with IC50 of 0.5 nM, weakly inhibits PI3Kβ and γ (>20-fold), no activity against PI3Kα. |
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| DC12443 | LASV inhibitor 3.3 Featured | LASV inhibitor 3.3 (LAMP1 inhibitor 3.3) is a specific inhibitor of Lassa fever virus (LASV, IC50=1.8 uM), inhibits LASV GP-mediated infection and cross-links to the LASV receptor, LAMP1, in cells; does not inhibits the GP-mediated infection of LCMV, LuJo |
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| DC12188 | Lathosterol Featured | Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis. |
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| DC9877 | Lauric Acid | Lauric Acid is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil. |
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| DC9512 | Lazabemide Featured | Lazabemide(Ro 19-6327/000) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively). |
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| DC22765 | LB-102 Featured | LB-102 (LB-1.2, LB 102) is a a selective dopamine D2/3/5-HT7 inhibitor. |
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| DC21221 | LB42908 | LB42908 is a highly potent, selective, orally active inhibitor of Ras farnesyltransferase (FTase) with IC50 of 0.9 nM against H-Ras and 2.4 nM against K-Ras.. |
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| DC21219 | LBL1 | LBL1 (Lamin A inhibitor LBL1) is a novel pyrroloquinazoline compound with significant anticancer activity, targets nuclear lamins and binds to the coiled-coil domain of lamin A (Kd=5.11 uM). |
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| DC22135 | LC-1028 | LC-1028 (LC1028) is a novel potent selective, covalent and irreversible inhibitor of p97 (valosin-containing protein), remains essentially irreversible ac tivity against p97 mutant C522A.. |
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| DC21222 | LCB 03-0110 | LCB 03-0110 is a potent, ATP-competitive inhibitor of Discoidin domain receptor (DDR) family and c-Src tyrosine kinase family, as well as Btk and Syk. |
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| DC21223 | LCB 03-0110 dihydrochloride | LCB 03-0110 is a potent, ATP-competitive inhibitor of Discoidin domain receptor (DDR) family and c-Src tyrosine kinase family, as well as Btk and Syk. |
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| DC23329 | LCH 7749944 Featured | LCH 7749944 (GNF-PF-2356) is a novel and potent PAK4 with IC50 of 14.93 uM, shows weak activity against other PAK family members. |
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| DC9626 | Lck Inhibitor | Lck Inhibitor is a new class of compounds that are potent inhibitors of Lck with an IC50 value of 7 nM. IC50 Value: 7 nM [1] Target: Lck in vitro: Lck Inhibitor (compound 25) exhibited good potency in the T-cell receptor-induced IL-2 secretion assay (I |
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| DC20006 | LCL521 | LCL521 is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase). |
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| DC21225 | LCS-1 | LCS-1 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.1-1.5 uM. |
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| DC21226 | LCS-1.28 | LCS-1.28 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.05-1.6 uM. |
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| DC21227 | LCS-1.34 | LCS-1.34 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.1-1.1 uM. |
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| DC7999 | LDC1267 Featured | LDC1267 is a highly selective TAM(Tyro3, Axl and Mer) kinase inhibitor with IC50 of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively. |
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| DC21228 | LDD1937 | LDD1937 is a novel potent FLT3 inhibitor with IC50 of 3 nM, displays >170-fold selectivity over JAK2/3, c-MET, IRAK-4. |
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| DC20433 | LDHA-IN-104 | LDHA-IN-104 is a potent and selective lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.87 uM, less potent for LDHB (IC50=6.9 uM). |
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| DC21230 | LDK1229 | LDK1229 is a novel potent, selective cannabinoid CB1 receptor inverse agonist with Ki of 220 nM. |
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| DC23787 | LDN 91946 | LDN 91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM, exhibits no activity against other cysteine hydrolase (UCH-L3, TGase 2, papain and caspase-3).. |
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| DC22459 | LDN-109657 | LDN-109657 is a novel SMN2 modulator that increase SMN protein levels in 3813 fibroblasts by twofold at 370 nM.. |
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| DC8231 | LDN-192960 2HCl Featured | LDN-192960 is a potent and selective inhibitor of haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase). IC50 = 0.010 µm |
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| DC7451 | LDN-193189 HCl Featured | LDN193189 HCl is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. |
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| DC7452 | LDN-211904 | LDN-211904 is an inhibitor of erythropoietin-producing hepatocellular carcinoma (Eph) receptors. |
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| DC22460 | LDN-75654 | LDN-75654 is a novel potent SMN2 modulator (EC50=1.8 uM. |
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| DC22461 | LDN-76070 | LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM. |
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| DC8775 | LED209 | LED209 is a potent QseC inhibitor that blocks both norepinephrine- and epinephrine-triggered QseC-dependent virulence gene expression at 5 pM in vitro. |
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| DC21231 | LEI-105 | LEI-105 is a potent, highly selective, and reversible dual DAGL-α/DAGL-β inhibitor with pIC50 pf 7.5/7.4 respectively. |
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