HIV-1 fusion inhibitor, targeting the membrane-proximal external region of Env spikes, specifically inhibiting the HIV-1 envelope-mediated membrane fusion by blocking CD4-induced conformational changes

Inhibitor of acetyl-CoA carboxylase (ACC), activating GPR40, inhibiting West Nile virus (WNV) infection and reducing the multiplication of Usutu virus (USUV), a WNV-related flavivirus

Desfluoro impurity of Ezetimibe

Precursor for PET imaging 11C-radiolabeled MK-6884

Primary metabolite of diazepam, binding to the GABA A receptor benzodiazepine modulatory site

PET precursor of preparing radiolabel [11C]HD-800, a high affinity brain penetrant PET tracer for imaging microtubules

Cysteine reactive protein labeling agent

Pro-drug of dexamethasone, anti-inflammatory glucocorticoid, stimulating glutamine uptake in the cerebral cortex

Glucocorticoid, Anti-inflammatory Agent

Cholecystokinin antagonist, selective for the CCKA subtype

Norepinephrine-dopamine reuptake inhibitor (NDRI)

Natural modulator of mu-, delta-, and kappa-opioid receptors

5-HT3 Receptor antagonist; Antitussive; Anti-inflammatory; Antiasthmatic

Potent Squalene Synthase Inhibitor

Cell-permeable, reversible and selective inhibitor of ɣ-secretase

Proteolysis targeting chimeras (PROTAC), potently decreasing FKBP12 abundance in MV4;11 cells, leading to over 80% reduction of FKBP12 at 0.1 μM and 50% reduction at 0.01 μM

Novel potent, orally active inhibitor of LTA4H

Selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2)

The major adduct formed by the food-borne carcinogen, PhIP with DNA

Novel human α-galactosidase A ligand, capable of stabilizing α-Gal A and restoring trafficking

Abundant lipid in the membranes of many algae, lower plants, and fungi, showing an inverse concentration relationship with phosphatidylcholine, being capable of replacing phosphatidylcholine

Novel HCV NS3 degrader, reducing susceptibility to resistance mutations, potently inhibiting HCV in a cellular infection model, exhibiting the most potent degradation (DC50 of 50nM at 4h) of HCV NS3,