| DC8675 |
Levodropropizine |
Levodropropizine is a histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive drug. |
|
| DC10257 |
Levofloxacin hydrate |
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. |
|
| DC22727 |
LGB-321 |
LGB-321 (LGB321) is a potent and specific pan-Pim inhibitor with Ki of 1/2.1/0.8 pM for Pim1/2/3, respectively. |
|
| DC22137 |
LGD2226
Featured
|
LGD-2226 (LGD2226) is an orally active, selective androgen receptor modulator (SARM) with binding Ki of 1 nM, >1000-fold selectivity over GR,PR, MR and ER. |
|
| DC10278 |
LGD-6972
Featured
|
LGD-6972 is a selective and orally active glucagon receptor antagonist. LGD-6972 has the potential for type 2 diabetes research. |
|
| DC25068 |
L-g-glutamyl-p-nitroanilide hydrochloride |
L-g-glutamyl-p-nitroanilide hydrochloride is a potent, competitive inhibitor of the neutral amino acid transporter ASCT2 (SLC1A5) with pKa of 13.79. |
|
| DC9895 |
L-Glutamic acid monosodium salt |
L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. |
|
| DC12206 |
L-Hexanoylcarnitine
Featured
|
L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease. |
|
| DC12612 |
LHF-535 |
LHF-535 (LHF535, LHF 535) is a small-molecule viral entry inhibitor that targets the arenavirus envelope glycoprotein, exhibits potent antiviral activity against a broad array of hemorrhagic fever arenaviruses with IC50 of 0.1-0.3 nM. |
|
| DC10312 |
L-Homocysteine thiolactone hydrochloride |
L-Homocysteine thiolactone hydrochloride is an intramolecular thioester of homocysteine; prevents translational incorporation of homocysteine into proteins. |
|
| DC8751 |
Licofelone |
Licofelone is a dual COX/LOX inhibitor being considered as a treatment for osteoarthritis. |
|
| DC10225 |
Lidocaine hydrochloride |
Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. |
|
| DC20198 |
Lifirafenib;BGB-283;Beigene-283 |
Lifirafenib (BGB-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant. |
|
| DC10099 |
BGB283 |
Lifirafenib（BGB-283） is a Novel potent and selective RAF Kinase and EGFR inhibitor. |
|
| DC21914 |
LIMK1 and 2 dual inhibitor |
LIMK1 and 2 dual inhibitor is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM). |
|
| DC21915 |
LIN28 inhibitor LI71
Featured
|
LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 7 uM, binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells. . |
|
| DC20436 |
Lin28-IN-1 |
Lin28-IN-1 is a small-molecule inhibitor of the Lin28/let-7 interaction with IC50 of 4.03 uM. |
|
| DC20982 |
Linopirdine dihydrochloride |
Linopirdine (DUP-996) is a potent Kv7 (KCNQ) voltage-gated potassium channels blcoker. |
|
| DC20983 |
Linopirdine |
Linopirdine (DUP-996. |
|
| DC26056 |
Liproxstatin-1 analog |
Liproxstatin-1 analog is an analog of the ferroptosis inhibitor liproxstatin-1 |
|
| DC23664 |
Lirimilast |
Lirimilast (BAY 19-8004. |
|
| DC12434 |
LIT-001 trifluoroacetate
Featured
|
LIT-001 trifluoroacetate (LIT001) is the first nonpeptide Oxytocin receptor (OT-R) agonist with EC50 of 55 nM, Emax=96%. |
|
| DC8689 |
Litronesib |
Litronesib is a selective, allosteric inhibitor of Eg5, which may result in mitotic disruption, apoptosis and consequently cell death in tumor cells that are actively dividing. |
|
| DC4138 |
Lixivaptan (VPA-985)
Featured
|
Lixivaptan is a highly potent, non-peptide, oral capsule that works by reducing the action of a hormone (vasopressin) that blocks fluid excretion. |
|
| DC21233 |
LJ 001
Featured
|
LJ 001 ((LJ-001, LJ001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1; specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion; specifically inhibits virus-cell but not cell-cell fusion |
|
| DC12172 |
L-JNKI-1 |
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK. |
|
| DC21234 |
LKY-047 |
LKY-047 is a decursin derivative that potently and selectively inhibits CYP2J2, competitively inhibits CYP2J2-mediated astemizole O-demethylase and terfenadine hydroxylase activity with Ki of 0.96 and 2.61 uM, respectively. |
|
| DC21235 |
LLL3 |
LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor, inhibits STAT3-dependent transcriptional and DNA binding activities. |
|
| DC20438 |
LLP2A |
LLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM. |
|
| DC21237 |
LLS2 |
LLS2 is a novel potent Galectin-1 (Gal1) inhibitor that decreases membrane-associated H-Ras and K-Ras and contributed to the suppression of pErk pathway. |
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