Cat. No. | Product name | CAS No. |
DCC3962 |
P18smi-22
Novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein |
1043924-66-8 |
DCC3963 |
P18smi-41
Novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein |
1111287-26-3 |
DCC3964 |
P217564
Second-generation active site-targeted covalent irreversible inhibitor of USP7 |
|
DCC3965 |
P-2281
Featured
Novel potent inhibitor of mTOR activity, significantly suppressing macroscopic and histologic abnormalities associated with chemically-induced murine ulcerative colitis. |
1112994-35-0 |
DCC3966 |
P2y1-in-16
Novel P2Y1 Antagonist |
870544-87-9 |
DCC3967 |
P505-15 Acetate
Selective spleen tyrosine kinase (SYK) inhibitor, suppressing leukocyte immune function and inflammation, and leading to a reduction in arthritis score and attenuated histological damage |
1370261-98-5 |
DCC3968 |
p53 Modulator 10d
Novel modulator of p53 activity, arresting at G2/M phase inducing delay of cell cycle progression |
1254366-81-8 |
DCC3969 |
P53 Reactivator C85
Novel reactivator of mutant p53, fuctioning as a zinc metallochaperone (ZMC) with diminished copper binding that functions as a chemotherapy and radiation sensitizer |
|
DCC3970 |
P5-peptide
Novel inhibitor of atherogenesis and diabetes, significantly and specifically inhibiting αD-CEP binding |
|
DCC3971 |
P7 Peptide
Novel bFGF antagonist peptide, inhibiting breast cancer cell growth |
|
DCC3972 |
P7c3a20
Neuroprotective agent, protecting ventral horn spinal cord motor neurons from cell death |
1260172-27-7 |
DCC3973 |
P97-in-17
Novel potent inhibitor of the AAA+ ATPase p97 |
|
DCC3974 |
P97-in-23
Novel potent inhibitor of the AAA+ ATPase p97 |
|
DCC3975 |
Pa Autoinducer
Pseudomonas aeruginosa autoinducer |
152833-54-0 |
DCC3976 |
Pa-082
Novel partial agonist of peroxisome proliferator-activated receptor-γ (PPARγ), recruiting PPARγ-coactivator-1α, preventing triglyceride accumulation, and potentiating insulin signaling in vitro |
95520-87-9 |
DCC3977 |
Pa1 Dihydrochloride
Photoswitchable epithelial sodium channel (ENaC) blocker |
1620951-72-5 |
DCC3978 |
Paba/no
Novel glutathione-S-transferase-p-activated nitric oxide donor, inhibiting proliferation and inducing apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells |
875769-11-2 |
DCC3979 |
Pad3-in-14b
Novel potent and selective inhibitor of protein arginine deiminase 3 (PAD3), having 15600 kinact/KI values and ≥10-fold selectivity for PAD3 over PADs 1, 2, and 4. |
|
DCC3980 |
pal-1045
Partial DAT/5-HT transporter substrate |
1374550-53-4 |
DCC3981 |
pal-1046
Full DAT/5-HT transporter substrate |
1374550-50-1 |
DCC3982 |
Pal-12
Novel selective LYPLAL1 activator, increasing LYPLAL1’s catalytic activity likely by enhancing the efficiency of the catalytic triad charge-relay system, confering beneficial effects in a mouse model of diet-induced obesity |
|
DCC3983 |
pal-287
Full DAT/5-HT transporter substrate; Non-neurotoxic releasing agent of serotonin, norepinephrine, and dopamine; Full agonist at 5-HT2B and partial agonist at 5-HT2C |
18085-03-5 |
DCC3984 |
Pal-545 Hydrochloride
Potent dual dopamine-serotonin (DA/5-HT) releaser |
1379932-98-5 |
DCC3985 |
Palbociclib Dihydrochloride
Featured
Selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 |
571189-11-2 |
DCC3986 |
Palmostatin M
Novel Ras-Signaling Modulator, targeting acyl protein thioesterase 1 (APT1) and 2 (APT2) in cells |
|
DCC3987 |
Palonosetron
Potent serotonin-3 (5-HT3) receptor antagonist |
135729-61-2 |
DCC3988 |
Pam2cys
Novel TLR2 agonist as potential adjuvant for cancer vaccines |
656831-18-4 |
DCC3989 |
Pancratistatin
Inhibitor of the Cell_cycle>cell cycle from G0/G1 to S phase with powerful antiparasite activity |
96281-31-1 |
DCC3990 |
Panduratin A
Biological Active Reagents |
89837-52-5 |
DCC3991 |
panomifene
Tamoxifen analogue; antiestrogenic |
77599-17-8 |
DCC3992 |
Pan-raf/rtk Inhibitor I-16
Novel potent pan-Raf and receptor tyrosine kinase inhibitor, potently inhibits all subtypes of Rafs with IC50 values of 3.49 (BRafV600E), 8.86 (ARaf), 5.78 (BRafWT), and 1.65 nM (CRaf), respectively |
|
DCC3993 |
Pao-pdt
Potent and highly selective small molecule inhibitor of thioredoxin reductase (TrxR) |
256348-71-7 |
DCC3994 |
Pape-1
Pathway Preferential Estrogen, activating the extranuclear signaling pathway without activity on the nuclear signaling pathway |
|
DCC3996 |
Para-aminoblebbistatin
Blebbistatin derivative, increasing water solubility, decreases the inherent fluorescence, stabilizing the molecule to circumvent its degradation by prolonged blue light exposure, and decreasing its phototoxicity while retaining the in vitro and in vivo a |
2097734-03-5 |
DCC3997 |
Para-cid-5951923
Isomer of CID-5951923 |
1303092-92-3 |
DCC3998 |
Para-nitroblebbistatin
Selective cell-permeable inhibitor of non-muscle myosin II ATPases, being more stable and less phototoxic than Blebbistatin |
1621326-32-6 |
DCC3999 |
Paraoxon
Acetylcholinesterase inhibitor, the active metabolite of the insecticide parathion |
311-45-5 |
DCC4000 |
Paraquat Diiodide
Non-selective contact herbicide, killing green plant tissue on contact, being highly toxic and linked to Parkinson's disease, generating reactive oxygen species (ROS), which causes cell death and potentially leading to acute respiratory distress syndrome |
336190-15-9 |
DCC4001 |
Parogrelil
Novel potent phosphodiesterase 3 inhibitor, suppressing the asthmatic response and showing both bronchodilating and anti-inflammatory effects |
139145-27-0 |
DCC4002 |
Parogrelil Hydrochloride
Novel potent phosphodiesterase 3 inhibitor, suppressing the asthmatic response and showing both bronchodilating and anti-inflammatory effects |
878796-94-2 |
DCC4003 |
Parp/brd4 Inhibitor Iii-16
Potent and Novel Dual PARP/BRD4 Inhibitor for Efficient Treatment of Pancreatic Cancer |
|
DCC4004 |
Parp1/brd4 Inhibitor Iii-7
Novel highly selective dual PARP1/BRD4 inhibitor (PARP1 IC 50 =49nM; BRD4 IC 50 =202nM), repressing the expression and activity of PARP1 and BRD4 to synergistically inhibit the malignant growth of pancreatic cancer cells in vitro and in vivo |
|
DCC4005 |
Parp10-in-22
Novel Selective Cell-Active Inhibitor of PARP10 |
|
DCC4006 |
Parpi-fl
Fluorescent PARP1 Inhibitor for Glioblastoma Imaging |
1380359-84-1 |
DCC4007 |
Parvifoline Aa
Natural ent-kaurane diterpenoid, markedly stimulates the expression of NKG2D ligands on hepatocellular carcinoma (HCC) cells, considerably enhancing their recognition and lysis by NK cells, covalently inhibiting peroxiredoxins I/II (Prxs-I/II) catalytic a |
|
DCC4008 |
Pav-866
Novel antiviral agent, potently against Rabies virus (RABV) targeting host-rabies virus protein-protein interactions |
|
DCC4009 |
Pazinaclone
Partial agonist at GABAA benzodiazepine receptors with sedative and anxiolytic effects |
103255-66-9 |
DCC4010 |
pbdnj0802
Novel potent inhibitor of |
1214721-13-7 |
DCC4011 |
pbdnj0804
Novel potent glucosidase inhibitor, suppressing HCV virion assembly and secretion, potently inhibiting DENV infection in vitro |
1214259-23-0 |
DCC4012 |
Pbi.105
Novel Inhibitor of Parasite Proliferation of Asexual Blood Stage P. falciparum Parasites |
|
DCC4013 |
Pbi.120
Novel Inhibitor of Parasite Proliferation of Asexual Blood Stage P. falciparum Parasites |
|
DCC4014 |
Pbi-1393
Novel enhancer of Th1 type cytokine production and primary T cell activation |
175072-12-5 |
DCC4015 |
Pbiilh2
Pyridobenzimidazole infraluciferin, an analog of D-luciferin, increasing bioluminescence activity while maintaining nIR bioluminescence |
|
DCC4016 |
P-bi-tat
Novel αvβ3 inhibitor, showing excellent efficacy in a glioblastoma multiforme (GBM) mouse model |
|
DCC4017 |
Pbs-1086
Novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein sub |
|
DCC4018 |
Pb-wut-01
Novel calcineurin inhibitor in the C. albicans cells, enhancing susceptibility of the cells |
|
DCC4019 |
pc-046
Potent tubulin-binding agent with anti-tumor efficacy in hematologic cancers |
1202401-59-9 |
DCC4020 |
Pc407-ws
Water-soluble novel potential COX-2 inhibitor |
1242169-24-9 |
DCC4021 |
Pcb153
Non-dioxin-like (NDL) congener |
35065-27-1 |
DCC4022 |
Pcb-te2p
Novel Chelator for Cu-64 |
|
DCC4023 |
Pcc-0105002
Novel PSD95-nNOS inhibitor, disrupting the PSD95-nNOS interaction, attenuating neuropathic pain, decreasing SNL-induced spinal dorsal horn WDR neuron hyperexcitation |
|
DCC4024 |
Pcc0208018
Novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) binding and not dire |
1673534-73-0 |
DCC4025 |
P-cf3-diepp
Novel α7 nAChR weak partial agonist, showing antinociceptive and anti-inflammatory properties |
|
DCC4026 |
p-chloro-diphenyl Diselenide
Organoselenium compound with antidepressant-like and memory enhancer actions |
20541-49-5 |
DCC4027 |
pcm126
Potent antagonist of the series disrupting EphA2-ephrinA1 interaction, blocking EphA2 phosphorylation in prostate cancer cells at low |
192876-13-4 |
DCC4028 |
p-come 102
Highly selective α1L adrenaline receptor agonist |
1354932-35-6 |
DCC4029 |
Pcpma-(1r,2r)-22e
Novel potent dopamine D3R agonist (Ki=4.1nM) |
|
DCC4030 |
Pcpma-(1r,2r)-30q
Novel potent and selective dopamine D3R partial agonist |
|
DCC4031 |
Pcpma-(1s,2s)-22e
Novel potent dopamine D3R antagonist |
|
DCC4032 |
Pcsk9 Modulator
Novel modulator of proprotein convertase subtilisin kexin like type 9 (PCSK9) |
|
DCC4033 |
Pcsk9-in-4d
Novel PCSK9 mRNA translation inhibitor |
|
DCC4034 |
Pcsk9-in-4g
Novel PCSK9 mRNA translation inhibitor |
|
DCC4035 |
Pcsk9-in-8b
Novel liver-targeted inhibitor of ribosomal synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) |
|
DCC4036 |
Pd-1 Inhibitor 16
Novel inhibitor of PD-I/PD-L1 interaction to be used as a negative immune checkpoint regulatory and antineoplastic agent |
2005454-12-4 |
DCC4037 |
Pd-1/pd-l1 Antagonist D2
Novel potent PD-1/PD-L1 antagonist (IC50 of 16.17 nM), activating the antitumor immunity of T cells efficiently in PBMCs |
|
DCC4038 |
Pd-1/pd-l1 Inhibitor 17
Novel bifunctional inhibitor of PD-1/PD-L1 interactions, promoting dimerization, internalization, and degradation of PD-L1, suppressing tumor growth in vivo by activating antitumor immunity |
|
DCC4039 |
Pd-1/pd-l1 Inhibitor A30
Novel Potent Inhibitor of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction |
|
DCC4040 |
Pd-1/pd-l1 Inhibitor Ch1
Novel inhibitor of PD-1/PD-L1 (IC 50 value of 56.58 nM), dose-dependently promoting HepG2 cell death in a co-culture model of HepG2/hPD-L1 and Jurkat T cells, effectively inhibiting tumor growth (TGI of 76.4% at 90 mg/kg) in an immune checkpoint humanized |
|
DCC4041 |
Pd-1/pd-l1 Inhibitor P18
Novel potent programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor (IC50 9.1 nM) |
|
DCC4042 |
Pd-128907 Hydrochloride
Selective D3 dopamine receptor agonist |
123594-64-9 |
DCC4043 |
Pd-151242
Selective antagonist for human ETA receptors |
155561-67-4 |
DCC4044 |
Pd160170
Neuropeptide Y Y1 receptor antagonist |
181468-88-2 |
DCC4045 |
Pd-160725 Isethionate
AMPA receptor antagonist |
1262769-92-5 |
DCC4046 |
Pd-161989 Isethionate
AMPA receptor antagonist |
1262770-05-7 |
DCC4047 |
Pd-174494
Novel, potent, and selective NR1/2B NMDA receptor antagonist |
193359-26-1 |
DCC4048 |
P-d1ago
Novel cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors |
|
DCC4049 |
Pd26-tl07
Novel selective inhibitor of STAT3 phosphorylation, binding to the SH2 domain of STAT3, exhibiting remarkable antiproliferative activity against three cancer cell lines (HCT-116, SW480 and MDA-MB-231) |
|
DCC4050 |
pda-66
Novel inducer of mitotic arrest and apoptosis in human progenitor and cancer cells |
1613633-78-5 |
DCC4051 |
Pdd4091
Novel G6PD inhibitor |
|
DCC4052 |
Pde5-in-42
Potent and selective second-generation phosphodiesterase type 5 (PDE5) inhibitor |
936449-28-4 |
DCC4053 |
Pde7 Inhibitor S14
Novel cell-permeable PDE7 inhibitor, targeting the cyclic adenosine monophosphate (cAMP)/cAMP-response element binding protein (CREB) pathway, exerting neuroprotection in an Alzheimer's disease (AD) model |
18741-24-7 |
DCC4054 |
Pde9-in-16
Novel selective PDE9 inhibitor with strong antioxidant activity, inhibiting Aβ aggregation as potential candidates for the treatment of Alzheimer’s disease |
|
DCC4055 |
Pde9-in-2
Novel Potent, Selective, and Orally Bioavailable Inhibitor against Phosphodiesterase-9 (PDE9) |
|
DCC4056 |
P-decylaminophenol
Novel inhibitor of melanogenesis |
23227-12-5 |
DCC4057 |
Pdf Inhibitor M-2
Novel Peptide Deformylase (PDF) Inhibitor |
|
DCC4058 |
Pdi-in-p1
Protein disulfide isomerase (PDI) inhibitor |
1461648-55-4 |
DCC4059 |
Pd-l1 Degrader F4
Novel PD-L1 degrader, showing 66.99% degradation activity at 20 μM with no calcium blocking effect, strengthening the T cell-mediated killing of tumor cells |
|
DCC4060 |
Pd-l1 Degrader P22
Novel PROTAC dual inhibitor and degrader of PD-L1, inhibiting PD-1/PD-L1 interaction with IC50 of 39.2 nM in an HTRF binding assay |
2447066-37-5 |
DCC4061 |
Pd-l1 Inhibitor L7
Novel Potent PD-L1 Inhibitor (IC50 1.8 nM), binding to human PD-L1 (hPD-L1) with a KD value of 3.34 nM, without showing any binding to hPD-1, blocking PD-1/PD-L1 interaction with an EC50 value of 375 nM |
|
DCC4062 |
Pdsinh-c01
Novel pendrin inhibitor, inhibiting Cl-/anion exchange mediated by mouse pendrin without affecting other major kidney tubule transporters |
|
DCC4063 |
Peg-vtx
Novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML) |
|
DCC4064 |
Pelorol
Activator of SHIP-1 |
287974-44-1 |
DCC4065 |
pemedolac
Cyclooxygenase Inhibitor and Prostagladin Synthase Inhibitor |
103024-44-8 |
DCC4066 |
Penb-l-glutamate
Novel caged glutamate |
|
DCC4067 |
Penclomedine
Antineoplastic agent, alkylating and crosslinking DNA, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis |
108030-77-9 |
DCC4068 |
Penicillic Acid
Mycotoxin with antibiotic and carcinogenic activity |
90-65-3 |
DCC4069 |
penicillin K
Antibiotic, a natural penicillin, synthesized in vitro by incubating (S-octanoyl)glutathione, 6-APA and AT |
525-97-3 |
DCC4070 |
Penindolone
Novel potent and broad-spectrum anti-influenza A virus (anti-IAV) activities with low risk of inducing drug resistance |
|
DCC4071 |
Pentamidine Dimesylate
Inhibitor of calcium-dependent complex formation with p53 [(Ca)S100B-p53] in malignant melanoma (MM), restoring p53 tumor suppressor activity in vivo |
6823-79-6 |
DCC4072 |
Peptide 1018
Innate defense regulator, target stringent response-controlled virulence in a Pseudomonas aeruginosa murine cutaneous infection model |
|
DCC4073 |
Peptide 4f
ApoA-I/HDL mimetic peptide, efficiently crossing the blood-brain barrier and modulating amyloid beta distribution between brain and plasma |
|
DCC4074 |
Peptide P9r
Broad-spectrum virus- and host-targeting peptide, inhibiting coronaviruses and other respiratory viruses |
|
DCC4075 |
Pergolide Mesylate
Agonist of dopamine receptor subtypes D1 and D2 |
66104-23-2 |
DCC4076 |
Peridinin
Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation |
33281-81-1 |
DCC4077 |
Perindopril
Non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor |
82834-16-0 |
DCC4078 |
Pet-16
Novel allosteric inhibitor of E. coli Hsp70 (DnaK) and human Hsp70 proteins |
34387-64-9 |
DCC4079 |
Pex14-pex5 Inhibitor-5
First Inhibitor of PEX14-PEX5 Protein-Protein Interaction (PPI) with Trypanocidal Activity |
|
DCC4080 |
Pf-03084014
Novel γ-secretase inhibitor |
865773-15-5 |
DCC4081 |
Pf-03671148
Dose dependent inhibitor of multiple fibrotic genes |
1378524-25-4 |
DCC4082 |
Pf-04363467 Hydrochloride
Selective dopamine D3/D2 receptor antagonist |
2040055-81-8 |
DCC4083 |
Pf-04671536 Hydrochloride
Novel potent and selective PDE8B/8A inhibitor |
1305116-67-9 |
DCC4084 |
pf-04859989
Irriversible inhibitor of kynurenine amino transferase II (KAT II) |
34783-48-7 |
DCC4085 |
Pf-05109794
Novel selective hTRPV4 Antagonist (hTRPV4 IC50 49nM; rTRPV4 IC50 1,150nM) |
|
DCC4086 |
Pf-05214030
Novel potent TRPV4 antagonist (hTRPV4 IC50 4nM; rTRPV4 IC50 27nM) |
1669444-50-1 |
DCC4087 |
Pf-06371900
Novel potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor |
1622291-81-9 |
DCC4088 |
Pf-06424439 Mesylate
Featured
Potent and selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2) |
1469284-79-4 |
DCC4089 |
Pf-06655075
Novel non-brain-penetrant long-acting peptide oxytocin (OT) receptor agonist with increased selectivity for the OT receptor and significantly increased pharmacokinetic stability |
|
DCC4090 |
Pf-06745013
Novel potent and selective inhibitor of MAP4K4 |
|
DCC4091 |
Pf-06756394
Novel tyrosine residues probe, rationally targeting active site |
|
DCC4092 |
Pf-06758955 Hydrochloride
Novel potent and selective inhibitor of MAP4K4 |
|
DC30002 |
PF-06835919
Featured
PF-06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF-06835919 is reported in patent US 20170183328 A1, example 4. Increased fructose consumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obesity, and insulin resistance in humans. Since ketohexokinase (KHK) is the principal enzyme responsible for fructose metabolism, identification of a selective KHK inhibitor may help to further elucidate the effect of KHK inhibition on these metabolic disorders. |
2102501-84-6 |
DCC4094 |
Pf-06843195 Prodrug
Novel prdrug of PF-06843195, a potent PI3Kα-selective inhibitor |
|
DCC4095 |
Pf-06939999
Novel SAM Competitive PRMT5 Inhibitor, Demonstrating Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance |
|
DCC4096 |
Pf1070a
Natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein |
146556-41-4 |
DCC4097 |
Pf-184563
Potent, selective non-peptidic antagonist of the V1a receptor |
748806-39-5 |
DCC4098 |
Pf-3604861
Novel dual H3/4 histamine receptor antagonist |
|
DCC4099 |
Pf-3837
Highly selective, extremely potent Mps1 kinase inhibitor |
|
DCC4100 |
Pf-4522654
Potent and selective 5-HT2C receptor agonist |
1065109-28-5 |
DCC4101 |
Pf-5177624
Selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells |
1350821-45-2 |
DCC4102 |
Pf-543 Hydrochloride
Featured
Novel, potent and specific inhibitor of sphingosine kinase-1 (SphK1) |
1706522-79-3 |
DCC4103 |
pf-5466
Antimalarial, actively against Plasmodium liver stages |
1353762-98-7 |
DCC4104 |
Pf-562271 Tosylate
Potent, ATP-competitive, reversible inhibitor of FAK |
939791-40-9 |
DCC4105 |
Pf-562771
Novel potent and selective inhibitor of the activation-loop mutant Kit phosphorylation and tumor growth |
834894-21-2 |
DCC4106 |
Pf-68742
Novel Entry Inhibitor of both CCR5- and CXCR4-Tropic Strains of Human Immunodeficiency Virus Type 1 (HIV-1), Targeting a Novel Site on gp41 |
|
DCC4107 |
Pf-7006
Highly selective, extremely potent Mps1 kinase inhibitor |
|
DCC4108 |
Pf-alkyne
Novel fluorophosphonate-based probe, specifically and covalently reacts with the tyrosine-111 residue of the Schistosoma japonicum GST (sjGST) tag, rapidly and site-selectively immobilizes sjGST fusion proteins |
|
DCC4109 |
Pf-cbp/brd4
Novel dual CBP/p300 and BRD4 bromodomain inhibitor, downregulating IL-6, IL-ß and IFN-ß in macrophages |
1962928-22-8 |
DCC4110 |
Pfi-7n
Negative control for PFI-7 (GLXC012596) |
|
DCC4111 |
Pfkrs1-in-5
Novel selective inhibitor of both Plasmodium and Cryptosporidium lysyl-tRNA synthetase, clearing parasites from mouse models of malaria and cryptosporidiosis infection. |
|
DCC4112 |
Pfn1-in-c1
Novel inhibitor of Profilin1 (Pfn1), reducing the overall level of cellular filamentous (F)-actin, slowing EC migration and proliferation, and inhibiting the angiogenic ability of EC both in vitro and ex vivo |
919010-46-1 |
DCC4113 |
Pfn1-in-c2
Novel inhibitor of Profilin1 (Pfn1), reducing the overall level of cellular filamentous (F)-actin, slowing EC migration and proliferation, and inhibiting the angiogenic ability of EC both in vitro and ex vivo |
919010-22-3 |
DCC4114 |
Pg490-88
Water soluble derivative pro-drug of PG490 (triptolide) |
195883-06-8 |
DCC4115 |
Pg-928310
Novel anti-HIF-1alpha agent |
514218-36-1 |
DCC4116 |
Pg97-269 Tfa Salt
Potent and selective antagonist of the VIP1 receptor, inhibiting competitively effect of VIP on the VIP1 receptor mediated stimulation of adenylate cyclase activity with Ki values respectively of 15 ± 5 nM and 2 ± 1 nM for the rat and human VIP1 receptor |
202463-00-1 |
DCC4117 |
Pgam1 Inhibitor Kh2
Novel allosteric PGAM1 inhibitor, showing efficacious in multiple preclinical models of pancreatic ductal adenocarcinoma (PDAC), especially with high PGAM1 expression |
|
DCC4118 |
Pgam1 Inhibitor Kh3
Novel allosteric PGAM1 inhibitor, showing efficacious in multiple preclinical models of pancreatic ductal adenocarcinoma (PDAC), especially with high PGAM1 expression |
|
DCC4119 |
Pge-2946979
Novel potent matrix metalloproteinase (MMP) inhibitor, targeting MMPs 1, 3, 9, and 13 (24, 18, 1.9, and 1.3 nM, respectively) |
380653-37-2 |
DCC4120 |
Pgmi-004a
Glycolytic enzyme phosphoglycerate mutase 1 (PGAM1) inhibitor |
1313738-90-7 |
DCC4122 |
pha-680626
Inhibitor of both Bcr-Abl tyrosine kinase and Aurora kinases |
398493-74-8 |
DCC4123 |
Pha-e429
Selective ATP competitive ALK inhibitor |
|
DCC4124 |
Phagocytosis Inhibitor
Inhibitor of phagocytosis, interacting with and inhibiting the activating Fc receptors on macrophages, inhibiting downstream signaling pathways driving Fc-mediated phagocytosis |
683208-21-1 |
DCC4125 |
Phantasmidine
Natural nicotinic acetylcholine receptor agonist |
|
DCC4126 |
Phar-095239
Novel COX-2 inhibitor |
257289-81-9 |
DCC4127 |
Phencyclidine Hydrochloride
Inhibitor of NMDA receptors, used as a veterinary anesthetic, and briefly as a general anesthetic for humans |
956-90-1 |
DCC4128 |
Phen-dc3
Selective ligand of a specific G-quadruplex conformation, interacting with the quadruplex through extensive |
929895-45-4 |
DCC4129 |
phenoxodiol Diacetate
Prodrug of phenoxodiol |
81267-66-5 |
DCC4130 |
Phenylarsine Oxide
Inhibitor of internalization of cell surface receptors and tyrosine phosphatases, with no effect on tyrosine kinase |
637-03-6 |
DCC4131 |
phenylmethimazole
Blocker of dsRNA-induced IRF3 nuclear translocation and homodimerization; Inhibitor of lipopolysaccharide-mediated Toll-like receptor-4 signaling; Inhibitor of human pancreatic cancer |
25433-13-0 |
DCC4132 |
Phnp-3
Novel selective α-syn ligand, exhibited the promising binding characteristics for α-syn aggregates (Ki = 0.52 nM) |
|
DCC4133 |
Phoenixin-14
Novel neuropeptide, protecting human brain vascular endothelial cells against oxygen-glucose deprivation/reoxygenation (OGD/R)-induced inflammation and permeability, significantly ameliorating HFD-induced obesity and fatty liver, regulating pituitary gona |
|
DCC4134 |
Phoenixin-20
Novel GPR173 agonist, promoting osteoblastic differentiation of MC3T3-E1 cells. stimulating mRNAs encoding hypothalamo-pituitary-gonadal hormones |
|
DCC4135 |
Phomoxanthone A
Natural anti-tumor agent, showing strong apoptotic anticancer effects against platinum-resistant solid cancers |
359844-69-2 |
DCC4136 |
Phosphatidylinositol
Potent antagonist of (H1N1)pdm09 infection, markedly suppressing cytopathic effects and attenuating viral gene expression in (H1N1)pdm09-infected MDCK cells |
383907-36-6 |
DCC4137 |
phospho-sulindac
Sulindac derivative with promising anticancer activities |
1421675-47-9 |
DCC4138 |
Phosphotyrosine
Inducer of platelet aggregation, playing a role in cellular signal transduction and possibly in cell growth control and carcinogenesis |
21820-51-9 |
DCC4139 |
Photac-i-3
Novel photoswitchable BET bromodomain Degrader (PHOTAC) |
2370997-94-5 |
DCC4140 |
Photoazolol-1
Novel potent photoswitchable antagonist for a precise spatiotemporal control of β2-adrenoceptors |
|
DCC4141 |
Photogbi1
Novel photocontrol inhibitor of the voltage-gated proton channel Hv1 |
2146094-34-8 |
DCC4142 |
Photo-lenalidomide-acid
Functionalized photoswitchable cereblon ligand for Degraders |
2363154-39-4 |
DCC4143 |
Photos1p
Novel photoswitchable sphingolipid probe, reversibly controlled S1P3-dependent pain hypersensitivity in mice and uniquely suited for the study of S1P biology in cultured cells and in vivo |
|
DCC4144 |
Photosensitizer Pz I
Novel porphyrazine-based photodynamic anti-cancer agent, inducing immunogenic cell death |
|
DCC4145 |
Photosensitizer Pz Iii
Novel porphyrazine-based photodynamic anti-cancer agent, inducing immunogenic cell death |
|
DCC4146 |
Photosph
Novel photoswitchable sphingolipid probe |
|
DCC4147 |
Phototrexate
Novel photoswitchable inhibitor of human dihydrofolate reductase |
2268033-83-4 |
DCC4148 |
Phyllospadine
Natural flavonoidal alkaloid from the sea-grass Phyllosphadix iwatensis |
76540-48-2 |
DCC4149 |
Physapubenolide
Natural cytotoxic withanolide antitumor agent, inducing apoptosis by decreasing mitochondrial membrane potential and elevating the Bax/Bcl-2 protein expression ratio |
100217-92-3 |
DCC4150 |
Physodic Acid
Natural inhibitor of Wnt signaling, modulating β-catenin-dependent transcription |
84-24-2 |
DCC4151 |
Pi-090
Platelet aggregation inhibitor |
1389318-66-4 |
DCC4152 |
Pi-091
Platelet aggregation inhibitor |
129051-63-4 |
DCC4153 |
Pi-2620
Novel Tau ligand, displaying high Tau binding, low MAO-A binding, high brain uptake, and fast and complete brain washout |
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DCC4154 |
Pi3k/akt/mtor-in-6be
Novel inhibitor of the PI3K/Akt/mTOR signaling pathways, activating P53 and inducing apoptosis |
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DCC4155 |
Pi3k/akt-in-c89
Novel Inhibitor of the PI3K-Akt Pathway, Inducing Autophagy of Female Germline Stem Cells |
1195621-75-0 |
DCC4156 |
Pi3kd/v-in-01
Highly potent ATP-competitive PI3Kdelta/Vps34 dual inhibitor |
1807551-44-5 |
DCC4157 |
Pi3ki1
Novel potent PI3K inhibitor with a modified omipalisib structure |
|
DCC4158 |
Pi3k-in-s1
Novel PI3K inhibitor, synergizing with sorafenib in non-small cell lung cancer cells involving the Akt-S6 signaling. |
|
DCC4159 |
Piboserod Hydrochloride
Selective 5-HT4 receptor antagonist |
178273-87-5 |
DCC4160 |
Picrasidine N
Novel Subtype-Selective PPARbeta/delta Agonist |
101219-62-9 |
DCC4161 |
Picumeterol
Potent and selective beta2-adrenoceptor agonist |
130641-36-0 |
DCC4162 |
Pikamilone Sodium
Prodrug of GABA, used for treatment of neurogenic bladder in spinal and benign prostatic hyperplasia |
62936-56-5 |
DCC4163 |
Pik-c98
Novel PI3K inhibitor, displaying potent preclinical activity against multiple myeloma |
691388-62-2 |