Cat. No. | Product name | CAS No. |
DC21334 |
MN-25
A potent, reasonably selective agonist of peripheral cannabinoid receptor with Ki of 11 nM for CB2, 22-fold selectivity over the psychoactive CB1 receptors (Ki=245 nM).. |
501926-82-5 |
DC21377 |
NESS-040C5
A potent, reasonably selective cannabinoid CB2 agonist with Ki of 0.4 nM, 25-fold selectivity over CB1 receptor.. |
1445751-90-5 |
DC11717 |
PD-321852
A potent, reasonably selective Chk1 inhibitor with cell IC50 of 5 nM. |
622856-21-7 |
DC12016 |
NB 001
A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition). |
686301-48-4 |
DC11958 |
CCG 258001
A potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 280 nM. |
2055990-96-8 |
DC11957 |
CCG 224061
A potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 66 nM. |
2055990-82-2 |
DC24036 |
DZ-2002
A potent, reversible type III inhibitor of SAHH (S-adenosyl-L-homocysteine hydrolase) with Ki of 17.9 nM. |
33231-14-0 |
DC22606 |
Narlaprevir
A potent, second generation HCV NS3 serine protease inhibitor with Ki of 6 nM. |
865466-24-6 |
DC20766 |
BETd-246
A potent, second-generation BET protein degrader that exhibits superior selectivity, potency and antitumor activity. |
2140289-17-2 |
DC20583 |
WNK inhibitor 7
A potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility.. |
2125724-72-1 |
DC21271 |
Volinanserin (MDL100907)
Featured
A potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors. |
139290-65-6 |
DC20851 |
BW-723C86
Featured
A potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes. |
160521-72-2 |
DC21285 |
MK-212
A potent, selective 5-HT2C receptor agonist with IC50 of 20 nM in HEK293 cells-exppressed 5-HT2C, shows weakly activity for 5-HT2A. |
61655-58-1 |
DC22915 |
ST-1535
A potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM. |
496955-42-1 |
DC12017 |
NKY80
A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively. |
299442-43-6 |
DC23941 |
RU-24969
Featured
A potent, selective agonist of 5-HT1A and 5-HT1B receptors, with preference for 5-HT1B. |
66611-26-5 |
DC23002 |
DAA-1097
A potent, selective agonist of PBR/TSPO that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM.. |
220551-79-1 |
DC22698 |
CE-326597
A potent, selective agonist of the human and rat CCK1 receptor with Ki of 36 nM. |
870615-40-0 |
DC20295 |
2-PCCA
A potent, selective agonist of the orphan GPR88 receptor with EC50 of 877 nM. |
1287205-42-8 |
DC24029 |
PF-4840154
A potent, selective agonist of the rat (EC50=97 nM) and human (EC50=23 nM) TRPA1 channel. |
1332708-14-1 |
DC23831 |
TASP0382088
A potent, selective ALK5 inhibitor with IC50 of 4.8 nM, >100-fold selectivity over 95 different kinases. |
1253941-85-3 |
DC20564 |
TBBz
Featured
A potent, selective and ATP-competitive CK2 inhibitor with Ki of 0.5-1 uM. |
577779-57-8 |