| DC21007 |
Befiradol
Featured
|
Befiradol (F13640, NLX 112) is a highly potent, selective 5-HT1A receptor agonist with Ki of 2.7 nM. |
|
| DC12290 |
Befiradol hydrochloride (F 13640 hydrochloride) |
Befiradol hydrochloride is a selective 5-HT1A receptor agonist. |
|
| DC20030 |
Begacestat (GSI-953) |
Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) for the treatment of Alzheimer's disease. |
|
| DC8160 |
ZGN-440(Beloranib) |
Beloranib is being studied as a first-in-class obesity therapy that demonstrates a unique mechanism of action through methionine aminopeptidase 2 (MetAP2 ) inhibition. |
|
| DC12278 |
Belvarafenib
Featured
|
Belvarafenib is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively. |
|
| DC20135 |
Bemesetron (MDL 72222) |
Bemesetron (MDL 72222) is a selective 5-HT3 receptor antagonist with an IC50 of 0.33 nM. Neuroprotective effect. |
|
| DC6908 |
Bendamustine HCL (SDX-105, Cytostasane)
Featured
|
Bendamustine HCL (Ribomustin, Treanda, SDX-105) is a DNA-damaging agent with IC50 of 50 μM. |
|
| DC12299 |
Benfluralin |
Benfluralin is a kind of herbicide and an agrochemical which can be used as a pre-emergence herbicide used for the control of grass and other weeds in a range of food and non-food crops. |
|
| DC20185 |
Benzamidine HCl |
Benzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively. |
|
| DC26053 |
Benzamil (hydrochloride)
Featured
|
Benzamil hydrochloride is a specific and potent sodium channel (ENaC) blocker. |
|
| DC22184 |
Benzarone |
Benzarone (NSC 82134) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=17 uM, EYA3), exhibits selectivity for EYA over PTP1B. |
|
| DC9885 |
Benzenesulfonamide |
Benzenesulfonamide ia an inhibitor of carbonic anhydrases |
|
| DC20028 |
Benznidazole (Synonyms: Benznidazol; Ro 07-1051; Ro 71051)
Featured
|
Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease. |
|
| DC10223 |
Benzocaine hydrochloride |
Benzocaine hydrochloride is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. |
|
| DC12173 |
Benzyl alcohol (Benzenemethanol) |
Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor. |
|
| DC20216 |
Benzylcetyldimethylammonium chloride hydrate |
Benzylcetyldimethylammonium chloride hydrate is a chemical. |
|
| DC22482 |
Bephenium hydroxynaphthoate |
Bephenium hydroxynaphthoate is an anthelmintic compound that acts as an activiator of nematode B-type nAChR, is used in the treatment of hookworm infections and ascariasis.. |
|
| DC22478 |
Bephenium |
Bephenium is an anthelmintic compound that acts as an activiator of nematode B-type nAChR, is used in the treatment of hookworm infections and ascariasis.. |
|
| DC8898 |
Bepotastine
Featured
|
Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. |
|
| DC21868 |
Berotralstat |
Berotralstat is a potent human plasma kallikrein inhibitor. |
|
| DC21519 |
Besifovir |
Besifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).. |
|
| DC11042 |
BET inhibitor CF53 |
BET inhibitor CF53 is a highly potent, orally active inhibitor of bromodomain and extra-terminal (BET) with Ki of <1 nM (BRD4 BD1). |
|
| DC21382 |
EIDD-1931(NHC)
Featured
|
EIDD-1931 (β-d-N4-Hydroxycytidine, NHC) inhibits both murine hepatitis virus (MHV) (EC50 of 0.17 μM) and Middle East respiratory syndrome CoV (MERS-CoV) (EC50 of 0.56 μM) with minimal cytotoxicity. It also inhibits SARS-CoV-2 and multiple 2 endemic, epide |
|
| DC8830 |
Betahistine
Featured
|
Betahistine is a strong affinity histamine H3 receptor antagonist and weak affinity agonist of histamine H1 receptors. |
|
| DC12320 |
Betanin |
Betanin has potent antioxidant and anti-inflammatory effect, that could inhibit peroxynitrite (ONOO-), with an IC50 of 19.2 μM. Betanin is a red glycoside obtained from beets that can be used as colorant. |
|
| DC8556 |
BET-BAY 002 |
BET-BAY 002 is a potent BET inhibitor; shows efficacy in a multiple myeloma model. |
|
| DC11566 |
BETd-260
Featured
|
BETd-260 (ZBC260, BETd260) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
|
| DC11567 |
BETd-260 trifluoroacetate |
BETd-260 trifluoroacetate (ZBC260, BETd 260 TFA) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
|
| DC12131 |
BF-227(E/Z)
Featured
|
BF 227 is a candidate for an amyloid imaging probe for PET, with a Ki of 4.3 nM for Aβ1-42 fibrils. |
|
| DC20797 |
BF 844 |
BF 844 (BioFocus 844) is a small molecules capable of stabilizing mutant USH3 mutation CLRN1(N48K). |
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