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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC2541 Hif-1alpha Inhibitor-1 Novel HIF-1alpha inhibitor
DCC2542 Hif-1alpha-p300 Ppi Inhibitor-3 Novel HIF-1alpha-p300 Protein Protein Interaction inhibitor
DCC2543 Hif-hydroxylase Modulator Novel hypoxia inducible factor hydroxylase modulator
DCC2544 Hif-hydroxylase Modulator-ii Novel hypoxia inducible factor hydroxylase modulator
DCC2545 Hif-in-33 Novel HIF Pathway Inhibitor
DCC2546 Himbacine Natural muscarinic receptor antagonist
DCC2547 Hipk1/2-in-a64 Novel Potent Inhibitor of HIPK1/HIPK2 Kinase
DCC2548 Hippeastrine Hydrobromide Natural alkaloid, demonstrating significant cytotoxicity against a panel of human and murine tumor cell lines
DCC2549 Histidine-proline Allosteric inhibitor of ATP phosphoribosyltransferase (ATPPRT), binding to the ATPPRT:ATP complex via a two-step binding mechanism, inhibiting ATPPRT competitively and likely uncompetitively, respectively, against PRPP and ATP
DCC2550 Histidyl-histidine Novel enhancer of catalytic efficiency of neurolysin
DCC2551 Histidyltyrosine Novel enhancer of catalytic efficiency of neurolysin
DCC2552 Hiv-1 In Photoprobe Novel photoaffinity-labeled probe for full-length human immunodeficiency virus-1 integrase (HIV-1 IN)
DCC2553 Hiv-1 Inhibitor 9d Novel highly potent HIV-1 inhibitor with broad-spectrum activity (EC50 = 2.0-57 nM) against resistant strains, exhibiting good solubility and safety profiles and a good PK profile with an oral bioavailability of 59% in rats
DCC2554 hjc0122 AMPA Receptor Positive Allosteric Modulator
DCC2555 Hjc0123 Novel orally bioavailable STAT3 inhibitor
DCC2556 Hjc0149 Novel potent orally bioavailable inhibitor of signal transducer and activator of transcription 3 (STAT3)
DCC2557 Hjc05100 Novel apigenin analogue, suppressing pancreatic stellate cell proliferation
DCC2558 Hk Inhibitor 2 Novel inhibitor of YycG histidine kinase (HK), showing potent antibiofim activity against Staphylococcus epidermidis
DCC2559 Hk2 Modulator-1 Novel allosteric hexokinase 2 (HK2) modulator, selectively detaching HK2 from the mitochondria
DCC2560 hl010183 Novel Metformin Derivative; Inhibitor of Proliferation and Invasion of Triple-Negative Breast Cancer Cells
DCC2561 Hl-3-68 Novel SARS-CoV-2 Main Protease (Mpro) inhibitor, binding to Subsites S1 and S2 (K d =0.69 µM)
DCC2562 hla20a Selective Acetylcholinesterase Inhibitor
DCC2563 Hlb-0532247 Novel phosphoramidate prodrug of ddhCTP, effectively reducing titers of Zika and West Nile viruses in cell culture with minimal nonspecific toxicity to host cells
DCC2564 Hlcl-61 First-in-class inhibitor of protein arginine methyltransferase 5 (PRMT5)
DCC2565 Hlö-7 Dimesylate Novel Nerve Agent Reactivator
DCC2566 Hm-50316 Potent and highly selective FABP4 inhibitor
DCC2567 Hm90822 Novel antagonist to the inhibitors of apoptosis (IAPs), potentiating cell death in EGFR-overexpressing non-small-cell lung cancer cells
DCC2568 Hmao-b Inhibitor 5 Novel highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action (IC 50 = 42 nM; SI > 2375)
DCC2569 Hmbpp Triammonium Salt Potent stimulator of gamma delta T cells
DCC2570 Hmi-1a3 Protein kinase C partial agonist, targeting the C1 domain, inhibiting cell proliferation, decreasing cell viability and inducing an apoptotic response

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