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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC2926 Kj-pyr-10 Novel specific inhibitor of MYC
DCC2927 Kkha-761 Potent D3 receptor antagonist with high 5-HT1A receptor affinity
DCC2928 Kl-1156 Novel NF-κB inhibitor and lipopolysaccharide (LPS)-induced nitric oxide production inhibitor
DCC2929 Kld-12 Self-assembling peptide, forming a hydrogel matrix to support growth of cells in the presence of an ionic solution, enhancing chondrogenic differentiation of bone marrow stromal cells (BMSCs)
DCC2930 Klebsazolicin Novel inhibitor of 70S ribosome by obstructing the peptide exit tunnel
DCC2931 Klk6-in-32 First-in-class inhibitor of Kallikrein-related peptidase 6 (KLK6), promoting the differentiation of OPCs into mature oligodendrocytes in vitro
DCC2932 Klk6-in-42 First-in-class inhibitor of Kallikrein-related peptidase 6 (KLK6), promoting the differentiation of OPCs into mature oligodendrocytes in vitro
DCC2933 Kl-l9p Novel antibiotic sensitizer, promoting the rearrangement of the bacterial membrane that enables hydrophobic antibiotics to permeate, strongly sensitizing Gram-negative bacteria to linezolid (Lzd), rifampicin (Rif), or clarithromycin (Clr)
DCC2934 Boc-phe-leu-glup(oph) 0
DCC2935 Km05382 CDK9 inhibitor, inhibiting transcription of GAPDH
DCC2936 km10340 Selective S1P3 agonist
DCC2937 Km-5-25 Novel inhibitor of the BfrB-Bfd complex, binding BfrB in the P. aeruginosa cytosol, blocking the BfrB-Bfd interaction and inhibiting iron mobilization from BfrB, resulting in cytosolic iron limitation that is manifested in a pyoverdine hyperproduction phe
DCC2938 Km-5-66 Novel inhibitor of the BfrB-Bfd complex, binding BfrB in the P. aeruginosa cytosol, blocking the BfrB-Bfd interaction and inhibiting iron mobilization from BfrB, resulting in cytosolic iron limitation that is manifested in a pyoverdine hyperproduction phe
DCC2939 kmi-1764 Novel BACE1 inhibitor with a non-acidic heterocycle at the P1' position
DCC2940 Kmn-010034 Novel Potent Hematopoietic Prostaglandin D2 Synthase (H-PGDS) Inhibitor
DCC2941 Kmn-80 Novel Potent and Selective EP4 Agonist
DCC2942 kms80013 Novel inhibitor of amyloid-
DCC2943 Kms88009 Novel inhibitor of amyloid-β aggregation, ameliorating the neurodegenerative disorder
DCC2944 Kmup-3 Novel enhancer of cGMP activity; Aortic smooth muscle relaxant
DCC2945 Kmup-4 Novel enhancer of cGMP activity; Aortic smooth muscle relaxant
DCC2946 Kongensin D Natural anti-TNBC agent, significantly suppressing the triple-negative breast cancer (TNBC) tumor growth without causing side effects
DCC2947 kp1212 Novel non-chain terminating nucleoside analog anti-HIV inhibitor
DCC2948 Kpt-6604 Novel selective, orally bioavailable, PAK4 allosteric modulator against triple negative breast cancer
DCC2949 Kpu-300 Novel potent antimicrotubule agent, exhibiting potent cytotoxicity against HT-29 cells by strongly binding to tubulin and inducing microtubule depolymn.
DCC2950 Kr-12-a4 Potent antimicrobial peptide against gram-positive and gram-negative bacteria and relatively high LPS-neutralization activity
DCC2951 Kr-25210 Novel enteroviral replication inhibitor through a non-capsid binding mode with EC 50 values of 2.5, 2.2, and 3.7 μM against hRV B14, A21, and A71, respectively, targeting the replication stages in the virus
DCC2952 Kr-31762 Novel KATP channel opener, exerting cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury
DCC2953 Kras(g12c)-in-1 Novel irreversible inhibitor of KRAS(G12C)
DCC2954 Kras4b-in-d14 Novel specific inhibitor of oncogenic KRAS4b signaling, stabilizing the KRAS4b-PDEδ complex and remarkably decreasing tumor size and triggered apoptosis of tumor cells
DCC2955 Kras4b-pdeδ Stabilizer C19 Novel stabilizer of the KRAS4b-PDEδ complex, decreasing the proliferation of colorectal cancer cells, and increasing apoptosis via decreased activation of oncogenic KRAS4b signaling

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