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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC2956 Krc-108 Novel potent multi-kinase inhibitor, targeting Ron, Flt3 and TrkA as well as c-Met
DCC2957 Krc-327 Selective novel inhibitor of c-Met receptor tyrosine kinase with anticancer activity.
DCC2958 Krm-ii-08 Novel potent, non-toxic, blood-brain barrier crossing, α5-GABA A R preferring ligand, enhancing a chloride-anion efflux that induces mitochondrial membrane depolarization and in response, TP53 upregulation and p53, constitutively phosphorylated at S392, c
DCC2959 Krn4884 Potassium channel opener
DCC2960 Krn-8602 Hydrochloride Topo II inhibitor, exhibiting cytotoxic effects against tumour cells
DCC2961 Krp-109 Novel neutrophil elastase (NE) inhibitor, decreasing expression of TGF-ß Signal Related Genes
DCC2962 Krp-199 Highly potent and selective antagonist for the AMPA receptors, exhibiting good neuroprotective effects in vivo
DCC2963 Krp-204 Novel highly selective β3-adrenoceptor agonist being developed for the treatment of diabetes and obesity
DCC2964 Ks-133 Novel Potent and Selective VIPR2 Antagonist, Counteracting Cognitive Decline in a Mouse Model of Psychiatric Disorders
DCC2965 Ksc-392-150 Novel inhibitor of the permeability transition pore (PTP)
DCC2966 kscm-1 Selective ligand of the sigma-1 receptor
DCC2967 Kscm-11 Ligand of the sigma receptor
DCC2968 kscm-5 Ligand of the sigma receptor
DCC2969 Ksk120 Novel inhibitor of transcriptional activity in Chlamydia trachomatis
DCC2970 Ksl-128114 Novel, highly potent, and metabolically stable peptide inhibitor of syntenin, Inhibiting Glioblastoma
DCC2971 Kspa-1 Novel modulator of kinesin spindle protein (KSP)/Eg5, activating KSP-catalyzed ATP hydrolysis in the absence of microtubules yet inhibiting microtubule-stimulated ATP hydrolysis by KSP
DCC2972 Kt-182 Potent and selective inhibitor of ABHD6
DCC2973 Kt2-962 TXA2/prostaglandin endoperoxide receptor antagonist
DCC2974 Kta-439 Thyroid hormone receptor β (TRβ) selective agonist
DCC2975 Ku-2285 Hypoxic cell radiosensitizer
DCC2976 Kufal194 Novel selective DYRK1A inhibitor
DCC2977 Kunb31 Novel potent and selective inhibitor of Hsp90β
DCC2978 Kurasoin B Novel protein farnesyltransferase inhibitor
DCC2979 kv1.5-in-iiii Potent Kv1.5 inhibitor
DCC2980 Kv2.1/syntaxin-in-cpd5 Novel neuroprotectant, inhibiting Kv2.1-syntaxin molecular interaction
DCC2981 Kva-d-88 Novel Preferable Phosphodiesterase 4B (PDE4B) Inhibitor, Decreasing Cocaine-Mediated Reward Properties in Vivo
DCC2982 Ky1022 Ras destabilizer, targeting the Wnt/ß-catenin pathway and inhibiting development of metastatic colorectal cancer
DCC2983 Kya1797 Novel inhibitor of the Wnt/ß-catenin pathway, binding directly to the regulators of G-protein signaling domain of axin, initiating ß-catenin and Ras degradation through enhancement of the ß-catenin destruction complex activating GSK3ß, effectively suppres
DCC2984 Kys05047 Selective T-type Ca(2+) channel blocker with anti-proliferative effects against various cancer cells
DCC2985 L-161240 Potent inhibitor of LpxC and lipid A biosynthesis

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