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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC2986 L-162782 Nonpeptide agonist of angiotensin AT1 receptor
DCC2987 L17er4 Novel cell-permeable attenuated cationic amphiphilic lytic (ACAL) peptide, efficiently bring immunoglobulin G (IgG) and other functional proteins into cells
DCC2988 L2-4048 Novel Migration Inhibitory Factor (MIF) inhibitor, binding at the allosteric and tautomerase sites, blocking MIF's tautomerase CD74 receptor binding, and pro-inflammatory activities
DCC2989 L458-bpyne Novel γ-secretase modulator photoaffinity probe, identifying distinct allosteric binding sites on presenilin that can be exploited to reduce levels of pathogenic Aβ species
DCC2990 L465046 (α-synuclein Amyloid Aggregation Inhibitor) Novel inhibitor of α-synuclein amyloid aggregation for the treatment of Parkinson's disease
DCC2991 L524-0366 Novel inhibitor of the TWEAK-Fn14 signaling cascade
DCC2992 L61h46 Novel potent inhibitor of human pancreatic cancer cells
DCC2993 L-651392 Potent leukotriene inhibitor
DCC2994 L-658758 Blocker of the activity of human neutrophil elastase (NE), human proteinase-3, human macrophage metalloelastase, mouse macrophage metalloelastase and Pseudomonas aeruginosa elastase
DCC2995 L-663581 Novel partial agonist of the benzodiazepine receptor
DCC2996 L-680833 Potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase (PMNL-E)
DCC2997 L-682679 HIV protease inhibitor
DCC2998 L-687306 Novel partial agonist of muscarinic M1 receptors
DCC2999 L-696229 HIV-1 non-nucleoside reverse transcriptase inhibitor
DCC3000 L-708906 Inhibitor of Human Immunodeficiency Virus Type 1 (HIV-1)
DCC3001 L-731988 Inhibitor of Strand Transfer, Preventing Integration and Inhibiting HIV-1 Replication in Cells
DCC3002 L-735821 Inhibitor of the KCNQ1 channel
DCC3003 L-739758 Potent glycoprotein IIb/IIIa inhibitor
DCC3004 L-744832 Ras farnesyltransferase inhibitor, inhibiting in p70(s6k) phosphorylation in mammary tumors, inducing tumor regression in transgenic mice by mediating alterations in both cell cycle control and apoptosis
DCC3005 L-749329 Dual ET(A)/ET(B) endothelin receptor antagonist
DCC3006 L-768673 Class III antiarrhythmic agent, selectively blocking the slowly activating cardiac delayed rectifier potassium current Iks
DCC3007 L-770644 Potent and selective agonist of the human beta3 adrenergic receptor
DCC3008 L-778123 Featured L-778123 is a dual FPTase and GGPTase-I inhibitor, with IC50s of 2 nM and 98 nM respectively.
DCC3009 L-841411 Novel HIV-1 integrase strand transfer inhibitor (INSTI), stabilizing an integrase-single blunt-ended DNA complex
DCC3010 L-858051 Chemically-modified forskolin with greater stability and water solubility than the parent compound
DCC3011 L-870812 Novel inhibitor of HIV-1 and SIV integrase
DCC3012 L-94901 The first organ-selective thyromimetic, lowering plasma low density lipoprotein (LDL) cholesterol and raising plasma high density lipoprotein (HDL) cholesterol levels
DCC3013 L-97-1 Adenosine A1 receptor antagonist, reducing allergic responses to house dust mite in an allergic rabbit model of asthma, improving survival and protecting the kidney in a rat model of cecal ligation and puncture induced sepsis, also improving survival and
DCC3014 Lamellarin D Top1mt inhibitor, targeting mitochondrial DNA
DCC3015 la-mem Glutamate receptor antagonist and radical scavenging agent

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