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Home > Inhibitors & Agonists > Cell Cycle/DNA Damage > Nucleoside Antimetabolite/Analog

Nucleoside Antimetabolite/Analog

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Cat. No. Product Name Field of Application Chemical Structure
DC81034 Methyl 16(Z)-pentacosenoate
Methyl 16(Z)-pentacosenoate is a fatty ester.
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DC81027 Menin-MLL-IN-36
Menin-MLL-IN-36 (compound 398) is an inhibitor of menin/MLL protein/protein interaction with an IC50 value of 0.043 μM in MEIS1 mRNA expression. Menin-MLL-IN-36 can be used in the research of cancer, myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), and diabetes.
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DC81026 Menin-MLL-IN-35
Menin-MLL-IN-35 (compound 286) is an inhibitor of menin/MLL protein/protein interaction with an IC50 value of 0.096 μM in MEIS1 mRNA expression. Menin-MLL-IN-35 can be used in the research of cancer, myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), and diabetes.
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DC81004 Mapinastine
Mapinastine is a biochemical assay reagent.
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DC80938 Lantadene B
Lantadene B is a triterpene component. Lantadene B can be isolated from the red variety of Lantana Camara. Lantadene B can be used in the research of cancer and inflammatory diseases.
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DC80925 KT-474 hydrochloride
KT-474 (KYM-001; PROTAC IRAK4 degrader-7) hydrochloride is an orally active PROTAC IRAK4 degrader with anti-tumor effects. KT-474 inhibits the cell cycle and induces apoptosis. KT-474 induces tumor regression in a xenograft model of MYD88-mutated ABC DLBCL. KT-474 is a click chemistry reagent, containing an alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
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DC80759 HAT-IN-10
HAT-IN-10 (Compound 12a) is an anti-human African trypanosomiasis (HAT) agent, with an EC50 value of 0.23 μM for T. brucei. HAT-IN-10 can be used for research on HAT.
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DC80719 GMNN modulator-1
GMNN modulator-1 is a GMNN modulator.
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DC80689 GABRA5 modulator-1
GABRA5 modulator-1 is a GABRA5 modulator.
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DC80672 Fmoc-Gly-Gly-Phe-Gly-Paclitaxel
Fmoc-Gly-Gly-Phe-Gly-Paclitaxel (Compound 16a-3) is a drug-linker conjugates for ADC. Fmoc-Gly-Gly-Phe-Gly-Paclitaxel contains the ADC linker Fmoc-Gly-Gly-Phe-OH and a potent tubulin polymerization inhibitor Paclitaxel. Fmoc-Gly-Gly-Phe-Gly-Paclitaxel can be used for the research of cancer.
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DC80618 Episterone
Episterone is a nucleoside metabolite.
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DC80558 Docosanoyl-CoA
Docosanoyl-CoA is a nucleoside metabolite.
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DC80530 DHFR-IN-25
DHFR-IN-25 (Compound N2) is a type of inhibitor of dihydrofolate reductase (DHFR). DHFR-IN-25 is a broad-spectrum and highly effective antibacterial agent, particularly showing significant effects on Candida albicans and Staphylococcus aureus. DHFR-IN-25 can be used for the study of local anti-infection.
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DC80520 Desferrioxamine X3
Desferrioxamine X3 is an agent that binds iron and aluminium.
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DC80511 DDB-S
DDB-S does not alter the protein binding properties of ICG, but increases its clearance rate. DDB-S can increase liver blood flow. DDB-S can be used to observe changes in liver blood flow.
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DC80505 DAMPA methyl ester
DAMPA methyl ester is an inhibitor of dihydrofolate reductase. DAMPA methyl ester can be studied in research on chemotherapy.
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DC80495 Cx43 HC-IN-1
Cx43 HC-IN-1 (Compound D4) is a selective and orally active inhibitor of connexin hemichannels (Cx43 HC). Cx43 HC-IN-1 effectively inhibits the hemichannel activity mediated by Cx43/Cx45 in denervated skeletal muscle fibers, significantly increasing the reinnervation rate of muscle fibers by neurons. Cx43 HC-IN-1 reduces neuroinflammation and neuronal overexcitation by inhibiting hemichannels in glial cells in the brain, and alleviates epilepsy in mice. Cx43 HC-IN-1 can be used for research on epilepsy and muscle diseases.
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DC80468 Corthrombin
Corthrombin (CVS 995) is a potent alpha-keto-amide thrombin inhibitor with Ki of 1 pM. Corthrombin can be used for the research of cardiovascular disease.
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DC80463 CMP-2-Aminoethylphosphonate
CMP-2-Aminoethylphosphonate is a nucleoside metabolite.
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DC80448 cis-Vaccenoyl chloride
cis-Vaccenoyl chloride is a fatty acid chloride.
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DC80429 Chitin, from crab carapace
Chitin, from crab carapace is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from crab carapace is found in the exoskeleton of crabs. Chitin, from crab carapace inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from crab carapace exerts antifungal and anti-inflammatory effects. Chitin, from crab carapace can be used in the research of gastric ulcer and candidiasis.
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DC80378 CB2 receptor agonist 4
CB2 receptor agonist 4 (Compound 8) is a highly selective cannabinoid receptor type 2 (CB2 Receptor) agonist with an EC50 of 13.99 nM. CB2 receptor agonist 4 shows no significant activity against cannabinoid receptor type 1. CB2 receptor agonist 4 can be used for the research of pain and immune-related diseases.
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DC80351 BTK degrader-2
BTK degrader-2 (Example 2) is a BTK dual-functional degrading agent, which causes the degradation of BTK through the ubiquitin-proteasome pathway. BTK degrader-2 can be used for the study of B-cell-related diseases.
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DC80336 BrAA-glycine-BG-PAB-Exatecan
BrAA-glycine-BG-PAB-Exatecan (Compound LD-11) is an Drug-Linker Conjugates for ADC, consisting of Exatecan and a linker. BrAA-glycine-BG-PAB-Exatecan can be conjugated with anti-ROR1 antibodies to form an ADC.\n
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DC80315 BKI 1708
BKI 1708 is a potent and orally active calcium-dependent protein kinase 1 (CDPK1) inhibitor (IC50 = 0.7 nM). BKI 1708 exhibits potent activity against Neospora (IC50 = 481 nM) and Toxoplasma (IC50 = 122 nM). BKI-1708 induces the formation of multinucleated complexes. BKI-1708 efficiently inhibits vertical transmission of both parasites and increases pup survival in mice.
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DC80308 BET-IN-29
BET-IN-29 (Compound 1) is a bromodomain and the terminal motif (BET) inhibitor. BET-IN-29 can be used for the study of cancer, inflammation, metabolism, neurological diseases, and infectious diseases.
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DC80306 Beta-alanyl-L-arginine
Beta-alanyl-L-arginine (β-Alanyl-L-arginine) is an intestinal microbial metabolite. Beta-alanyl-L-arginine can be used for the study of schizophrenia.
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DC80304 Benzobarbital
Benzobarbital is an active low-toxicity inductor of the liver monooxygenase system. Benzobarbital raises cytochrome P-450 concentration. Benzobarbital can be used in the research of post-ischemic liver disease.
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DC80276 AURKA-IN-4
AURKA-IN-4 (compound 13), a capsaicin-derived prohibitin ligand, is an AURKA inhibitor. AURKA-IN-4 acts as a molecular glue within the AURKA/PHB2/LC3 complex. AURKA-IN-4 is specific to the mitochondrial pool of AURKA, and inhibits AURKA-dependent mitophagy. AURKA-IN-4 can be used for cancer research.
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DC80254 Argimesna (ethanesulfonate)
Argimesna ethanesulfonate is a uroprotective agent. Argimesna ethanesulfonate is promising for research of hemorrhagic cystitis in cancer chemotherapy.
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