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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC76220 | 2'-F-AMP |
2'-F-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC76219 | 2'-F-ADP |
2'-F-ADP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC76218 | 2-Amino-ATP tetrasodium |
2-Amino-ATP tetrasodium is an ATP substitute produced by inserting an amino acid at the C2 position of ATP.
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| DC76217 | 2′-O-MOE-CMP |
2′-O-MOE-CMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC76216 | 2′-O-MOE-AMP |
2′-O-MOE-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC76215 | 2′-OMe-UMP |
2′-OMe-UMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC76214 | 2′-OMe-UDP |
2′-OMe-UDP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC76213 | 2′-OMe-GDP |
2′-OMe-GDP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC76212 | 2′-OMe-ADP |
2′-OMe-ADP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC76211 | 2′-F-UDP |
2′-F-UDP is a nucleotide analog that can be used in the synthesis of oligonucleotides.
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| DC7762 | RX-3117 Featured |
RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity.
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| DC73210 | TH7528 Featured |
TH7528 is a SAMHD1 inhibitor with IC50 of 4.5 μM/2.8 μM/2.6 μM against dGTP/Cl-F-ara-ATP/ara-CTP, respectively.
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| DC73203 | DI-87 Featured |
DI-87 ((R)-DI-87) is a highly potent, specific, orally bioavailable deoxycytidine kinase (dCK) inhibitor with IC50 of 3.15 nM.
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| DC73208 | PSB-0963 |
PSB-0963 (PSB0963) is a potent, selective ecto-5'-Nucleotidase (eN, CD73) inhibitor with Ki of 150 nM, >100-fold selectivity over NTPDases.
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| DC73207 | PSB-0952 |
PSB-0952 (PSB0952) is a potent, selective ecto-5'-Nucleotidase (eN, CD73) inhibitor with Ki of 260 nM, >150-fold selectivity over NTPDases and P2Y receptor subtypes P2Y2, P2Y4, P2Y6, and P2Y12.
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| DC73206 | PSB-071 |
PSB-071 (PSB071) is a small molecule inhibitor of nucleoside triphosphate diphosphohydrolases (NTPDase).
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| DC73205 | JLT048 |
JLT048 is a small molecule inhibitor of tyrosyl-DNA-phosphodiesterases 1 and 2 (TDP1 and TDP2) with IC50 of 7.7 and 32 uM, respectively.
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| DC73204 | F-aza-T-dCyd |
F-aza-T-dCyd (NSC801845) is a novel cytidine analog and is more efficacious than aza-T-dCyd in cell culture and mouse xenograft studies in HCT-116 human colon carcinoma.
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| DC10332 | Methylthio-DADMe-Immucillin A; MTDIA Featured |
MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP) with a Ki of 90 pM.
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| DCAPI1525 | 5-Azacytidine Featured |
5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves t
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| DC10318 | Acelarin Featured |
Acelarin (NUC-1031) is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine.
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| DC44975 | 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine Featured |
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
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| DC72845 | N4-Benzoyl-3’-O-methylcytidine |
N4-Benzoyl-3’-O-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
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| DC72843 | 2’-O-Methyl-N1-methyladenosine |
2’-O-Methyl-N1-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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| DC72842 | 3’-Deoxy-methyl-2-thiouridine |
3’-Deoxy-methyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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| DC72019 | Fludarabine triphosphate trisodium |
Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine, is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 μM and a Ki of 6.1 μM. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
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| DC7522 | Triapine Featured |
Triapine is a potent ribonucleotide reductase inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.
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| DC8940 | Raltitrexed Featured |
Raltitrexed(ZD1694), an inhibitor of thymidylate synthase, is an antimetabolite drug used in cancer chemotherapy.
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| DC9799 | CNDAC Featured |
CNDAC is the active component of sapacitabine.
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| DC72173 | L-Cytidine |
L-Cytidine is an L-configurational form of Cytidine. L-Cytidine is a pyrimidine nucleoside, a component of RNA. Cytidine can control the glial glutamate cycle, affect brain phospholipid metabolism, catecholamine synthesis and mitochondrial function.
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