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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC7897 BMS-582949 HCl Featured BMS-582949 is a dual action p38 Kinase Inhibitor.
DC22033 BMS-595 BMS-595 (BMS595) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 1.3 nM (CKα).
DC24131 BMS-599626 hydrochloride BMS-599626 (AC-480) is a potent, selective inhibitor of EGFR and HER2 with IC50 of 20 nM and 30 nM.
DC7730 Temsavir(BMS-626529) Featured BMS-626529 is a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T-cells.
DC20805 BMS-641988 BMS-641988 is a potent, selective, nonsteroidal androgen receptor antagonist with Ki of 1.7 nM, MDA-MB-453 cell IC50 of 16 nM.
DC20811 BMS-654457 BMS-654457 is a potent, reversible and direct inhibitor of factor XIa (FXa) with Ki of 0.4 nM.
DC22034 BMS-699 BMS-699 (BMS699) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 0.1 nM (CKα).
DC23482 BMS-741672 BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain..
DC20813 BMS-751324 BMS-751324 is a novel clinical prodrug of BMS-582949, which is a highly selective p38α MAPK inhibitor with IC50 of 13 nM.
DC20814 BMS-795311 BMS-795311 is a potent and orally available CETP inhibitor with IC50 of 3.8 nM, inhibits cholesteryl ester (CE) transfer with IC50 of 0.22 uM.
DC7089 BMS-806 (BMS 378806) BMS-806 (BMS 378806) is a small molecule gp120/CD4 inhibitor with an IC50 of median 5 nM.
DC10494 BMS813160 Featured BMS-813160 is a dual CCR2/CCR5 chemokine antagonist.
DC12670 BMS-817378 free base Featured BMS-817378 is a prodrug of the dual Met/VEGFR-2 inhibitor BMS-794833.
DC23526 BMS-817399 BMS-817399 is a potent, selective, orally bioavailable CCR1 antagonist with binding IC50 of 1 nM, inhibits MIP-1α-induced chemotaxis with IC50 of 6 nM.
DC12635 BMS-818251 BMS-818251 (BMS818251) is a novel potent, small-molecule inhibitor of HIV-1 entry with EC50 of 0.019 nM against e laboratory-adapted HIV-1 strain NL4-3.
DC20815 BMS-823778 Featured BMS-823778 (BMS823778) is an orally available, potent and selective inhibitor of 11βHSD-1 with IC50 of 2.3 nM, displays >10,000-fold selectivity over 11βHSD-2.
DC12512 BMS-823778 free base BMS-823778 (BMS823778) is an orally available, potent and selective inhibitor of 11βHSD-1 with IC50 of 2.3 nM, displays >10,000-fold selectivity over 11βHSD-2.
DC7090 BMS-863233 (XL-413) Featured BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity.
DC23891 BMS-869780 BMS-869780 is a potent γ-secretase modulator (GSM) that decreases Aβ1-42 (IC50=5.1 nM) and Aβ1-40 (IC50=25.1 nM) and increases Aβ1-37 and Aβ1-38 without inhibiting overall levels of Aβ peptides or other APP processing intermediates.
DC20817 BMS-871 BMS-871 is a potent, orally active pan-Notch inhibitor with IC50 of 4/1/4/3 nM for Notch1/2/3/4, respectively.
DC20818 BMS-884775 BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM.
DC20819 BMS-919373 BMS-919373 is a potent I(Kur)/Kv1.5 channel blocker with IC50 of 50 nM, with selectivity versus hERG, Na, Ca channels and reduced the level of brain penetration.
DC23872 BMS-932481(BMS932481;BMS 932481) Featured BMS-932481 (BMS932481) is a potent, selective, orraly active γ-secretase modulator (GSM), shows selectivity for Aβ40 and Aβ42 reduction (IC50=6.6 nM) while sparing total Aβ levels both in vitro and in vivo.
DC22445 BMS-933043 BMS-933043 is a novel highly selective, potent α7 nAChR partial agonist with binding Ki of 3.3 and 8.1 nM for rat and human α7, respectively.
DC23411 BMS-952048(BMS952048;BMS 952048) BMS-952048 is a positive allosteric modulator of mGluR5 with EC50 of 10 nM..
DC21092 BMS-955176 Featured BMS-955176 (GSK-3532795) is a second-generation HIV-1 maturation inhibitor that exhibits potent activity (EC50=3.9±3.4 nM) against a library (n=87) of gag/pr recombinant viruses.
DC20820 BMS-961955 BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively.
DC20821 BMS-962212 Featured BMS-962212 is a potent, highly selective and reversible small molecule coagulation Factor XIa (FXIa) inhibitor with Ki of 0.7 nM.
DC23143 BMS-983970 BMS-983970 (BMS983970) is a potent, orally active, pan-Notch inhibitor, demonstrates robust anti-tumor activity at tolerated doses in multiple tumor xenograft models..
DC22035 BMS-984923 BMS-984923 (BMS-984923) is a potent silent allosteric modulator (SAM) of mGluR5 with competitive antagonism of MPEPy binding with Ki of 0.6 nM, but has no detectable agonist and antagonist activity at mGluR5 signaling.

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