DC7897 |
BMS-582949 HCl
Featured
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BMS-582949 is a dual action p38 Kinase Inhibitor. |
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DC22033 |
BMS-595 |
BMS-595 (BMS595) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 1.3 nM (CKα). |
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DC24131 |
BMS-599626 hydrochloride |
BMS-599626 (AC-480) is a potent, selective inhibitor of EGFR and HER2 with IC50 of 20 nM and 30 nM. |
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DC7730 |
Temsavir(BMS-626529)
Featured
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BMS-626529 is a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T-cells. |
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DC20805 |
BMS-641988 |
BMS-641988 is a potent, selective, nonsteroidal androgen receptor antagonist with Ki of 1.7 nM, MDA-MB-453 cell IC50 of 16 nM. |
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DC20811 |
BMS-654457 |
BMS-654457 is a potent, reversible and direct inhibitor of factor XIa (FXa) with Ki of 0.4 nM. |
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DC22034 |
BMS-699 |
BMS-699 (BMS699) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 0.1 nM (CKα). |
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DC23482 |
BMS-741672 |
BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.. |
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DC20813 |
BMS-751324 |
BMS-751324 is a novel clinical prodrug of BMS-582949, which is a highly selective p38α MAPK inhibitor with IC50 of 13 nM. |
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DC20814 |
BMS-795311 |
BMS-795311 is a potent and orally available CETP inhibitor with IC50 of 3.8 nM, inhibits cholesteryl ester (CE) transfer with IC50 of 0.22 uM. |
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DC7089 |
BMS-806 (BMS 378806) |
BMS-806 (BMS 378806) is a small molecule gp120/CD4 inhibitor with an IC50 of median 5 nM. |
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DC10494 |
BMS813160
Featured
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BMS-813160 is a dual CCR2/CCR5 chemokine antagonist. |
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DC12670 |
BMS-817378 free base
Featured
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BMS-817378 is a prodrug of the dual Met/VEGFR-2 inhibitor BMS-794833. |
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DC23526 |
BMS-817399 |
BMS-817399 is a potent, selective, orally bioavailable CCR1 antagonist with binding IC50 of 1 nM, inhibits MIP-1α-induced chemotaxis with IC50 of 6 nM. |
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DC12635 |
BMS-818251 |
BMS-818251 (BMS818251) is a novel potent, small-molecule inhibitor of HIV-1 entry with EC50 of 0.019 nM against e laboratory-adapted HIV-1 strain NL4-3. |
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DC20815 |
BMS-823778
Featured
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BMS-823778 (BMS823778) is an orally available, potent and selective inhibitor of 11βHSD-1 with IC50 of 2.3 nM, displays >10,000-fold selectivity over 11βHSD-2. |
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DC12512 |
BMS-823778 free base |
BMS-823778 (BMS823778) is an orally available, potent and selective inhibitor of 11βHSD-1 with IC50 of 2.3 nM, displays >10,000-fold selectivity over 11βHSD-2. |
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DC7090 |
BMS-863233 (XL-413)
Featured
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BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. |
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DC23891 |
BMS-869780 |
BMS-869780 is a potent γ-secretase modulator (GSM) that decreases Aβ1-42 (IC50=5.1 nM) and Aβ1-40 (IC50=25.1 nM) and increases Aβ1-37 and Aβ1-38 without inhibiting overall levels of Aβ peptides or other APP processing intermediates. |
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DC20817 |
BMS-871 |
BMS-871 is a potent, orally active pan-Notch inhibitor with IC50 of 4/1/4/3 nM for Notch1/2/3/4, respectively. |
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DC20818 |
BMS-884775 |
BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM. |
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DC20819 |
BMS-919373 |
BMS-919373 is a potent I(Kur)/Kv1.5 channel blocker with IC50 of 50 nM, with selectivity versus hERG, Na, Ca channels and reduced the level of brain penetration. |
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DC23872 |
BMS-932481(BMS932481;BMS 932481)
Featured
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BMS-932481 (BMS932481) is a potent, selective, orraly active γ-secretase modulator (GSM), shows selectivity for Aβ40 and Aβ42 reduction (IC50=6.6 nM) while sparing total Aβ levels both in vitro and in vivo. |
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DC22445 |
BMS-933043 |
BMS-933043 is a novel highly selective, potent α7 nAChR partial agonist with binding Ki of 3.3 and 8.1 nM for rat and human α7, respectively. |
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DC23411 |
BMS-952048(BMS952048;BMS 952048) |
BMS-952048 is a positive allosteric modulator of mGluR5 with EC50 of 10 nM.. |
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DC21092 |
BMS-955176
Featured
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BMS-955176 (GSK-3532795) is a second-generation HIV-1 maturation inhibitor that exhibits potent activity (EC50=3.9±3.4 nM) against a library (n=87) of gag/pr recombinant viruses. |
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DC20820 |
BMS-961955 |
BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively. |
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DC20821 |
BMS-962212
Featured
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BMS-962212 is a potent, highly selective and reversible small molecule coagulation Factor XIa (FXIa) inhibitor with Ki of 0.7 nM. |
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DC23143 |
BMS-983970 |
BMS-983970 (BMS983970) is a potent, orally active, pan-Notch inhibitor, demonstrates robust anti-tumor activity at tolerated doses in multiple tumor xenograft models.. |
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DC22035 |
BMS-984923 |
BMS-984923 (BMS-984923) is a potent silent allosteric modulator (SAM) of mGluR5 with competitive antagonism of MPEPy binding with Ki of 0.6 nM, but has no detectable agonist and antagonist activity at mGluR5 signaling. |
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