Cas No.: | 86408-72-2 |
Chemical Name: | Ecabet sodium |
Synonyms: | Ecabet sodium;(1R-(1-alpha,4a-beta,10a-alpha))-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-1-phenanthrenecarboxylic acid sodium salt;12-sulfodehydroabietic acid 12-sodium salt pentahydrate;12-Sulfodehydroabietic acid monosodium salt;1-Phenanthrenecarboxylic acid,1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-,monosodium salt,(1R,4aS,10aR);Ecabetsodiumsalt;Gastrom;ta-2711 |
SMILES: | CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@]2(C)CCC[C@@]3(C)C(=O)[O-])S(=O)(=O)O.[Na+] |
Formula: | C20H27O5S-.Na+ |
M.Wt: | 402.48018 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Ecabet sodium (TA-2711) is currently applied to some clinical gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication[1]. Ecabet sodium reduces apoptosis[2]. |
References: | [1]. Wang Y, et al. Efficacy and safety of ecabet sodium as an adjuvant therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. Helicobacter. 2014 Oct;19(5):372-81. [2]. Rah YC, et al. Ecabet sodium alleviates neomycin-induced hair cell damage. Free Radic Biol Med. 2015 Dec;89:1176-83. |