| DC12637 |
Finerenone
Featured
|
Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease. |
|
| DC8200 |
Firategrast(SB-683699)
Featured
|
Firategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). |
|
| DC21015 |
FIT-039
Featured
|
FIT-039 is a potent, selective CDK9 inhibitor with IC50 of 5.8 uM for CKD9/cyclin T1, suppresses the replication of HSV-1 (IC50=0.69 uM). |
|
| DC9845 |
FITM
Featured
|
FITM is a nove mGlu1 inhibitor. FITM shows high affinity (Ki = 2.5 nM, fig. S2) and selectivity for mGlu1 over mGlu5. |
|
| DC20386 |
Pioglitazone
Featured
|
Pioglitazone is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. |
|
| DC21016 |
FJ 5002 |
FJ 5002 is a potent telomerase inhibitor with IC50 of 2 uM, a close derivative of MKT077. |
|
| DC22093 |
FKGK18 |
FKGK18 (FKGK18) is a potent, selective inhibitor of iPLA2 (group VIA Ca2+-independent phospholipase A2) with IC50 of 50 nM. |
|
| DC20019 |
Flagelin 22(TFA) (Flagellin 22(TFA)) |
Flagelin 22 TFA, a fragment of bacterial flagellin, is an effective elicitor in both plants and algae. |
.gif)
|
| DC11414 |
Flavoxate Hydrochloride
Featured
|
Flavoxate Hydrochloride(DW-61 Hydrochloride) is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic. |
|
| DCAPI1347 |
Fleroxacin (Quinodis) |
Fleroxacin (Quinodis) |
|
| DC7415 |
FLI-06
Featured
|
FLI-06 is a novel potent and selective small molecule intercepting Notch signaling and the early secretory pathway (EC50 ~2.3 μM). |
|
| DC9321 |
Flibanserin
Featured
|
Flibanserin is a novel multifunctional serotonin agonist and antagonist (MSAA) that improves sexual functioning in premenopausal women who suffer from reduced sexual interest and desire.
|
|
| DC8230 |
FLT3-IN-1(SKLB4771)
Featured
|
FLT3-IN-1(SKLB4771) is a novel potent and selective Flt3 inhibitor with IC50 of 10 nM; against FLT3-ITD-expressing MV4-11 cells with IC50 of 6 nM. |
|
| DC9060 |
Flubendazole |
Flubendazole is a potent broad spectrum anthelmintic. |
|
| DCAPI1375 |
Fluconazole |
Fluconazole |
|
| DCAPI1108 |
Flucytosine (Ancobon) |
Flucytosine (5-Fluorocytosine, 5-FC, Ancobon) is an antifungal drug with IC50 of 0.12 μg/mL in C.albicans. |
|
| DC5889 |
Fludarabine
Featured
|
Fludarabine (Synonyms: F-ara-A; NSC 118218) is a prodrug converted to free nucleoside 9-β-D-arabinosyl-2-fluoroadenine (F-ara-A). F-ara-A enters cells and accumulates as 5’-triphosphate. Interferes with DNA synthesis and repair. |
|
| DC4190 |
Fludarabine phosphate
Featured
|
Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis. |
|
| DC8337 |
Fluensulfone
Featured
|
Fluensulfone is a new nematicide of the fluoroalkenyl thioether group that has significantly reduced environmental impact with low toxicity to non-target insects and mammals. |
|
| DC11413 |
Flumatinib
Featured
|
Flumatinib is a multi-kinase inhibitor with IC50 Values of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRβ and c-Kit respectively. |
|
| DCAPI1180 |
Flumequine |
Flumequine |
|
| DC8910 |
Flunarizine dihydrochloride
Featured
|
Flunarizine is a selective calcium entry blocker. |
|
| DCAPI1301 |
Fluocinolone acetonide (Flucort-N) |
Fluocinolone acetonide (Flucort-N) |
|
| DCAPI1161 |
Fluocinonide(Vanos) |
Fluocinonide(Vanos) |
|
| DC22475 |
FITC
Featured
|
Fluorescein isothiocyanate(FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. |
|
| DC10424 |
Fluorescein-5-maleimide
Featured
|
Fluorescein-5-maleimide is a fluorescent thiol-reactive dye used to conjugate fluorescein to proteins (excitation: 494 nm, emission: 519 nm). |
|
| DC9669 |
Fluoroclebopride
Featured
|
Fluoroclebopride is useful chemical for PET image study. |
|
| DC10238 |
Fluoxymesterone |
Fluoxymesterone is an Androgen. The mechanism of action of fluoxymesterone is as an Androgen Receptor Agonist. |
|
| DC12247 |
Fluspirilene (R 6218; Redeptin)
Featured
|
Fluspirilene is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM. Fluspirileneis a long-acting injectable depot antipsychotic drug used for schizophrenia. |
|
| DC10020 |
Fluticasone furoate
Featured
|
Fluticasone furoate is a synthetic trifluorinated corticosteroid with potent anti-inflammatory activity. |
|
