| DC7126 |
QNZ(EVP4593)
Featured
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EVP4593 is a derivative of 6-aminoquinazoline class that has been previously isolated as an inhibitor of PMA/PHA-induced NF-κB pathway activation in Jurkat cells (IC50= 9 nM). |
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| DC7578 |
Exatecan (Mesylate)
Featured
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Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. |
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| DC21005 |
EXEL-0346 |
EXEL-0346 (EXEL0346) is a novel potent, orally active Glucosylceramide synthase (GCS) inhibitor with IC50 of 2 nM. |
|
| DC8260 |
Exemestane(FCE 24304)
Featured
|
Exemestane(FCE 24304) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively. |
|
| DC22518 |
Exenatide |
Exenatide (Exendin-4) is a 39-aa peptide, highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM. |
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| DC22517 |
Exendin-4 acetate
Featured
|
Exenatide acetate (Exendin-4 acetate) is the acetate of Exenatide, which is highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM.. |
|
| DC9532 |
ADH-1 trifluoroacetate
Featured
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Exherin (ADH-1) trifluoroacetate is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities; selectively and competitively binds to and blocks N-cadherin.
|
|
| DC10905 |
Exo1
Featured
|
Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 µM). |
|
| DC7204 |
Ezatiostat(TER199; TLK199)
Featured
|
Ezatiostat(TER199; TLK199) is a glutathione analog inhibitor of glutathione S-transferase (GST) P1-1. |
|
| DC20377 |
EZH2-IN-3 |
EZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1 with IC50 of 21/197/213 nM for wt EZH2/EZH2 Y641N/wt EZH1 respectively. |
|
| DC9821 |
Ezutromid
Featured
|
Ezutromid is a novel Small utrophin's translation modulator with EC50 of 0.4 uM . |
|
| DC20379 |
Factor D inhibitor 6 |
Factor D inhibitor 6 is a potent and selective, orally bioavailable inhibitor of Factor D with IC50 of 30 nM. |
|
| DC23545 |
Factor D inhibitor 7 |
Factor D inhibitor 7 is a potent and selective, orally bioavailable inhibitor of Factor D with IC50 of 50 nM. |
|
| DC21899 |
Fadaltran |
Fadaltran is a α2-adrenoreceptor antagonist.. |
|
| DC21900 |
FAK inhibitor 5 |
FAK inhibitor 5 is the first highly potent, selective irreversible inhibitor of the FAK kinase with IC50 of 0.6 nM. |
|
| DCAPI1576 |
Falecalcitriol |
Falecalcitriol |
|
| DC21650 |
Famitinib |
Famitinib (SHR1020) is a structural analogue of sunitinib, novel and potent multi-targeted RTK inhibitor, including c-Kit, VEGFR2/3, PDGFRβ, FLT-1/3 receptor and c-RET. |
|
| DC10910 |
Fantofarone
Featured
|
Fantofarone is a calcium channel blocker. |
|
| DC20380 |
Faropenem |
Faropenem is an orally active beta-lactam antibiotic with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes. |
|
| DC24118 |
C75
Featured
|
C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM). |
|
| DC20381 |
Fasentin
Featured
|
Fasentin is a novel inhibitor of glucose uptake (GLUT) that sensitizes cancer cells to FAS-induced cell death, preferentially inhibits GLUT4 (IC50=68 uM) over GLUT1. |
|
| DC22759 |
FAS-IN-1 |
FAS-IN-1 is a potent inhibitor of fatty acid synthase (FAS) wtih IC50 of 10 nM.. |
|
| DC10403 |
FAS-IN-1 Tosylate |
FAS-IN-1 tosylate is a potent inhibitor of fatty acid synthase (FAS) extracted from patent WO 2012064642 A1, compound 29; has an IC50 of 10 nM. |
|
| DC10213 |
Fatostatin
Featured
|
Fatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. |
|
| DC23119 |
FB23-2(FTO Demethylase inhibitor FB23-2)
Featured
|
FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM. |
|
| DC23507 |
FC131
Featured
|
FC131 (cyclo(-D-Tyr-Arg-Arg-Nal-Gly-)) is a selective, cyclopentapeptide CXCR4 antagonist with IC50 of 126 nM, exhibits anti-HIV activity in assays using NL4-3 and IIIB strains with EC50 of 21 nM.. |
|
| DC9753 |
FCCP
Featured
|
FCCP is a very potent uncoupler of oxidative phosphorylation in mitochondria,that disrupts ATP synthesis by transporting protons across cell membranes. |
|
| DC23678 |
FCPR03 |
FCPR03 is a novel potent, selective PDE4 inhibitor with IC50 of 60, 31 and 47 nM for PDE4CAT (PDE4 catalytic domain), PDE4B1 and PDE4D7, respectively. |
|
| DC25015 |
FD-44 |
FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model. |
|
| DC26037 |
FDL-169
Featured
|
FDL-169 is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector being developed by Flatley Discovery Lab for treating cystic fibrosis (CF) patients who carry the F508del mutation |
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