| DC21151 |
IR415 |
IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease. |
|
| DC9493 |
IRAK inhibitor 6 |
IRAK inhibitor 6 is interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor . |
|
| DC23594 |
Irampanel |
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
|
| DC23566 |
Irampanel hydrochloride |
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
|
| DC7173 |
Irbesartan
Featured
|
Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM. |
|
| DC8771 |
Tucatinib (Irbinitinib,ARRY-380)
Featured
|
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR. |
|
| DC22411 |
Irdabisant hydrochloride |
Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
|
| DC22419 |
Irdabisant |
Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
|
| DC20422 |
IRE1α-IN-3 |
IRE1α-IN-3 is a novel, potent IRE1α RNase inhibitor with EC50 of 0.82 uM. |
|
| DC23051 |
Irigenin
Featured
|
Irigenin, an α-glucosidase inhibitor, which has anti-inflammatory, anti-cancer, and anti-metastatic effects. Irigenin can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable |
|
| DC4180 |
Irinotecan Hydrochloride
Featured
|
Irinotecan hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. |
|
| DC22097 |
IS-741 |
IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2).. |
|
| DC10340 |
ISA-2011B |
ISA-2011B is a PIP5Kα inhibitor with promising anticancer effects . |
|
| DC23284 |
ISA27 |
ISA27 is a novel small molecule that blocks p53-MDM2 interaction and induces apoptosis both in vitro and in vivo. |
|
| DC9891 |
Isatin |
Isatin is an endogenous MAO inhibitor. |
|
| DC8120 |
Isavuconazole |
Isavuconazole(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557, exhibits MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata. |
|
| DC11341 |
Isavuconazonium (sulfate) |
Isavuconazonium is a water-soluble prodrug form of the azole antifungal isavuconazole (ISA). |
|
| DCAPI1264 |
Isepamicin |
Isepamicin |
|
| DC8427 |
Isepamicin Sulphate |
Isepamicin Sulphate is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit. |
|
| DC21153 |
ISO-66 |
ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM. |
|
| DC22118 |
ISO-92 |
ISO-92 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity with IC50 of 0.55 uM.. |
|
| DC12146 |
Isoastragaloside IV |
Isoastragaloside IV is a triterpene oligoglycoside isolated from Astragali Radix. |
|
| DC23058 |
Corylifolinin(Isobavachalcone)
Featured
|
Isobavachalcone is a natural chalcone first isolated from P. corylifolia that displays antibacterial, antifungal, anticancer, anti-reverse transcriptase, antitubercular, and antioxidant activities in various research models. |
|
| DC21133 |
Isobutyl-deoxynyboquinone |
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner. |
|
| DC20010 |
Isocarboxazid |
Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase, with an IC50 of 4.8 μM for rat brain monoamine oxidase in vitro. |
|
| DC12071 |
Isocryptotanshinone |
Isocryptotanshinone is a potent signal transducer and activator of transcription 3 (STAT3) and protein tyrosine phosphatase 1B PTP1B inhibitor, with an IC50 of 56.1 μM for PTP1B. |
|
| DC23768 |
Isoginkgetin |
Isoginkgetin (Iso-ginkgetin. |
|
| DCAPI1396 |
Isoliquiritigenin |
Isoliquiritigenin |
|
| DC23110 |
Isoliquiritin
Featured
|
Isoliquiritin has significant antidepressant-like, antifungal and anti-cancer activities. It induces apoptotic cell death through upregulating p53 and p21 in the A549 non-small cell lung cancer cells and inhibit the p53-dependent pathway and showed crosst |
|
| DC22328 |
Isomaltose
Featured
|
Isomaltose is a glucose disaccharide with an α-(1→6) linkage, as opposed to the α-(1→4) linkage found in maltose. |
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