DC20462 |
MNK-IN-54 |
MNK-IN-54 is a potent, orally bioavailable dual MNK1/2 and BCR-ABL1 inhibitor with IC50 of 20/10/200/10 nM for Abl T315I/ wt Abl/MNK1/MNK2, respectively. |
|
DC12496 |
Mofezolac
Featured
|
Mofezolac is a Highly Selective Cyclooxygenase-1 Inhibitors,Counteracting Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation. |
|
DCAPI1029 |
Moguisteine
Featured
|
Moguisteine is a novel peripheral non-narcotic antitussive drug. |
|
DC9425 |
Molindone (hydrochloride) |
Molindone is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses. |
|
DC22320 |
Mollugin
Featured
|
Mollugin is a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. |
|
DC8991 |
Molsidomine |
Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine, which is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound. |
|
DCAPI1363 |
Mometasone furoate |
Mometasone furoate |
|
DCAPI1006 |
Monobenzone (Benoquin) |
Monobenzone (Benoquin) |
|
DC7690 |
MMAD
Featured
|
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. |
|
DC7685 |
MMAF
Featured
|
Monomethylauristatin F(MMAF) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than MMAE; antibody drug cytotoxin. |
|
DC20042 |
Monooctyl succinate |
Monooctyl succinate is a monoester, which can be used as a surfactants and a potential fragrance releaser. |
|
DC8931 |
Mosapride |
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist. |
|
DC12485 |
Mosedipimod |
Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro. |
|
DCAPI1331 |
Moxonidine |
Moxonidine |
|
DCAPI1572 |
Moxonidine hydrochloride |
Moxonidine hydrochloride |
|
DC22554 |
MP-A08 |
MP-A08 is a first-in-class, highly selective, ATP competitive sphingosine kinase (SphK) inhibitor (Ki of 6.9/27 uM for SK2/SK1). |
|
DC22290 |
Aranidipine (MPC1304)
Featured
|
MPC1304 is a Ca2+ channel antagonist with potent and long-lasting antihypertensive effects. IC50 & Target: Ca2+ Channel. |
|
DC8339 |
MPEP hydrochloride
Featured
|
MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 μM. |
|
DC1015 |
MPEP
Featured
|
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM. |
|
DC20464 |
mPGES1-IN-16 |
mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM. |
|
DC20465 |
mPGES1-IN-17d |
mPGES1-IN-17d is a potent, selective mPGES-1 inhibitor with enzyme IC50 of 8 nM, A549 cell IC50 of 16.24 nM, human whole blood IC50 of 249.9 nM. |
|
DC23974 |
Mps1-IN-3
Featured
|
Mps1-IN-3 is a selective and highly potent Mps1 kinase inhibitor with IC50 of 50 nM. |
|
DC9542 |
MPTP (hydrochloride)
Featured
|
MPTP HCl induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats
|
|
DC23877 |
MRK-560 |
MRK-560 is a potent, brain-penetrant and orally bioavailable γ-secretase inhibitor that inhibits proteolytic cleavage of APP over the Notch pathway. |
|
DC23655 |
MRK-623 |
MRK-623 is a potent, α2/α3 subunit functionally selectiviie GABAA receptor agonist.. |
|
DC23616 |
MRK-696 |
MRK-696 is a non-selective benzodiazepine receptor partial agonist.. |
|
DC21923 |
MRK-A |
MRK-A is a potent, highly selective, brain penetrant inhibitor of mutant IDH1 with IC50 of 5 nM, displays a 10,000-fold mutant to wildtype selectivity ratio. |
|
DC21343 |
MRL-1237 |
MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein. |
|
DC23711 |
MRL20 |
MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM. |
|
DC20220 |
MRS-1845
Featured
|
MRS 1845 is a potent calcium channel protein inhibitor and inhibits capacitative Ca2+ influx in HL-60 cells (IC50 = 1.7 mM). |
|