| DCAPI1397 |
Orlistat (Alli, Xenical)
Featured
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Orlistat is a drug designed to treat obesity. Orlistat's primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. Orlistat is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet. |
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| DC23573 |
ORM-10962 |
ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, significantly reduces inward/outward NCX currents with IC50 of 55 and 67 nM, respectively. |
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| DCAPI1297 |
Orotic acid (6-Carboxyuracil) |
Orotic acid (6-Carboxyuracil) |
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| DC22407 |
Orvepitant |
Orvepitant (GW823296) is a potent and selective, brain penetrant NK1 receptor antagonist with pKi of 10.2. |
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| DC23149 |
Oseltamivir acid |
Oseltamivir acid (GS 4071, Ro 64-0802, Oseltamivir carboxylate) is a potent inhibitor of influenza neuraminidase (NA) with Ki of <1 nM for both A and B strains,showed potent activity against COVID-19(SARS-COV-2). |
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| DC8554 |
OSI-420
Featured
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OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells. |
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| DC9974 |
Isturisa (Osilodrostat)
Featured
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Osilodrostat is an inhibitor of aldosterone synthase and aromatase, for treating Cushing’s disease. |
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| DC11438 |
Osimertinib analogue
Featured
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Osimertinib analogue (C-005) is a potent EGFR inhibitor, which is 2-5 fold more selective than Osimertinib between above EGFR mutants and wild-type EGFR(A431) cells. |
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| DC21449 |
OSMI-1
Featured
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OSMI-1 is a cell-permeable, small molecule O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 uM. |
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| DC12453 |
OSMI-4 |
OSMI-4 (OGT inhibitor 4b) is a novel potent, selective, cell-active O-linked N-acetylglucosamine transferase (OGT) inhibitor with EC50 of ~3 uM. |
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| DC22304 |
ILK-IN-2 (CPD 22: OSU-T315 analog)
Featured
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ILK-IN-2 (OSU-T315 analog) is a ILK inhibitor. |
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| DC21450 |
OSW-1
Featured
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OSW-1 is a natural anti-enterovirus and anti-cancer compound that targets oxysterol-binding protein (OSBP) with Ki of 26 and 54 nM for OSBP and ORP4L, respectively. |
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| DC9501 |
Otilonium (bromide) |
Otilonium Bromide is an antimuscarinic used as a spasmolytic agent.
|
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| DC12312 |
OTX008 (Calixarene 0118; PTX008)
Featured
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OTX008 is a selective inhibitor of galectin-1. |
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| DC7150 |
Birabresib (OTX015)
Featured
|
OTX-015 is a new potent BRD2/3/4 inhibitor with evident anti-proliferative activity in several cell lines representative of mature B-cell tumors. |
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| DC22719 |
OUP-16 |
OUP-16 is a potent H4R agonist with a considerable selectivity over H3R.. |
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| DC23553 |
o-vanillin |
o-vanillin (C29L. |
|
| DC21022 |
OX-14 |
OX-14 is a highly potent farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 2.46 nM, with significantly lower binding affinity to hydroxyapatite. |
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| DC8676 |
Oxadiazon |
Oxadiazon is a preemergent herbicide. |
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| DC10480 |
Oxamflatin
Featured
|
Oxamflatin is a potent inhibitor of histone deacetylases (IC50 = 15.7 nM). |
|
| DCAPI1236 |
Oxfendazole |
Oxfendazole |
|
| DCAPI1110 |
Oxibendazole |
Oxibendazole |
|
| DC8961 |
Potassium Oxonate |
Oxonic acid potassium salt is an inhibitor of uricase, oxonic inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate catalyzed by pyrimidine phosphoribosyl-transferase in a different manner from allopurinol in cell-free extracts and inta |
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| DC10232 |
Oxybenzone |
Oxybenzone is a benzophenone derivative used as a sunscreen agent. |
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| DC9112 |
Oxybutynin HCl |
Oxybutynin is also a possible treatment of hyperhidrosis (hyper-active sweating) . |
|
| DC20489 |
Oxythiamine chloride hydrochloride |
Oxythiamine chloride is a small molecule transketolase inhibitor with Kd of 33 nM, shows functional assay of human transketolase inhibition in HCT-116 cells with EC50 of 26 nM. |
|
| DC12352 |
Oxythiamine (Hydroxythiamin) |
Oxythiamine, an antimetabolite and a vitamin B1 antagonist, is a well-known thiamine antagonist and inhibitor of transketolase. |
|
| DCAPI1345 |
Ozagrel HCl |
Ozagrel HCl |
|
| DC9445 |
Ozagrel (sodium) |
Ozagrel(OKY-046) sodium salt is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.
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|
| DC7222 |
P005091(P5091)
Featured
|
P005091(P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM. |
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