| DC5188 |
Sarecycline(P005672 hydrochloride)
Featured
|
P005672 is a phase II drug for antibacterial/anti-inflammatory acne treatment. |
|
| DC11234 |
P053 |
P053 (P-053, CerS1 inhibitor P053) is a potent, selective, orally active inhibitor of ceramide synthase 1 (CerS1) with IC50 of 0.5 uM, displays >10-fold selectivity for inhibition of CerS2, CerS4, CerS5, and CerS6. |
|
| DC7221 |
P22077
Featured
|
P22077 is a potent inhibitor of ubiquitin-specific protease (USP) 7 (EC50=8.6 uM), P22077 also inhibits the closely related deubiquitinase (DUB) USP47. |
|
| DC20490 |
p32 inhibitor M36 |
p32 inhibitor M36 is a novel small molecule inhibitor of p32 mitochondrial protein, binds directly to p32 and inhibits p32 association with LyP-1. |
|
| DC23112 |
p38 MAPK-IN-4 |
p38 MAPK-IN-4 is a potent and selective inhibitor of p38 MAPK with IC50 of 68 nM for p38α, inhibits LPS-induced TNFα release in THP-1 cells with IC50 of 187 nM. |
|
| DC20001 |
p38α inhibitor 1 |
p38α inhibitor 1 is a p38α inhibitor extracted from patent WO 2008076265 A1. |
|
| DC10798 |
p38-α MAPK-IN-1
Featured
|
p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. |
|
| DC21934 |
P516-0475 |
P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM). |
|
| DC23317 |
P53R3 |
P53R3 is a novel p53 reactivator that restores sequence-specific DNA binding of the endogenously expressed p53(R175H) and p53(R273H) mutants in gel-shift assays. |
|
| DC21520 |
P62-mediated mitophagy inducer |
P62-mediated mitophagy inducer (PMI) is a small molecule P62-mediated mitophagy inducer that activates mitophagy without recruiting Parkin or collapsing membrane potential and retains activity in cells devoid of a fully functional PINK1/Parkin pathway. |
|
| DC7677 |
P7C3-A20
Featured
|
P7C3-A20 is an analogue of P7C3，a proneurogenic, neuroprotective agent. |
|
| DC22060 |
PAC1 |
PAC1 (Compound PAC1) is a novel PROTAC antibody conjugate, more potent estrogen receptor-alpha (ERα) degrader compared to PROTAC without antibody conjugation.. |
|
| DC7477 |
pac-1
Featured
|
PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3. |
|
| DC12200 |
PACAP (6-38), human, ovine, rat TFA |
PACAP (6-38), human, ovine, rat is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively. |
|
| DC8638 |
Paclitaxel
Featured
|
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. |
|
| DC21408 |
Pactamycin |
Pactamycin (NSC 52947) is a potent protein synthesis inhibitor, inhibits protein synthesis at the translocation step on the 70S ribosome, has activity against Gram-positive and Gram-negative bacteria, and broad antitumor, antiviral, and antiplasmodial act |
|
| DC11113 |
Padsevonil |
Padsevonil (UCB-0942, UCB0942) is a potential anti-seizure agent that functions as a pre- and post-synaptic inhibitor.. |
|
| DC21454 |
P11
Featured
|
PAFAH inhibitor P11 (P11) is a potent, selective platelet-activating factor acetylhydrolases PAFAH1b2 and PAFAH1b3 inhibitor with IC50 of 40 nM and 900 nM respectively. |
|
| DC7659 |
Palifosfamide
Featured
|
Palifosfamide is a novel molecule for the treatment of sof tissue sarcoma. |
|
| DC10362 |
Palmitelaidic Acid |
Palmitelaidic acid is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue. |
|
| DC20491 |
Palmostatin B |
Palmostatin B is a potent Acyl protein thioesterase 1 (APT1. |
|
| DC8459 |
Palovarotene(R 667)
Featured
|
Palovarotene (R-667, RO-3300074) is a selective retinoic acid receptor gamma(RAR-γ) agonist for the treatment of emphysema. |
|
| DCAPI1259 |
Pamidronate Disodium |
Pamidronate Disodium |
|
| DCAPI1175 |
Pamidronic acid |
Pamidronic acid |
|
| DC20769 |
Pamiparib
Featured
|
Pamiparib (BGB-290, BGB290) is a highly potent, selective and brain penetrant PARP1/2 inhibitor with potent anti-tumor activity. |
|
| DC4107 |
Panadiplon (U-78875) |
Panadiplon (U-78875) is an anxiolytic drug with a novel chemical structure that is not closely related to other drugs of this type. |
|
| DC20492 |
Pandacostat |
Pandacostat is the first nonselective HDAC inhibitor (pan-HDACi) with Ki of 0.12/0.07/0.95/0.18/0.032/1.1/0.5/1.4 uM for HDAC1/2/3/4/5/6/7/8/9, respectively. |
|
| DC12642 |
pan-PIM inhibitor 17 |
pan-PIM inhibitor 17 is a potent, selective, orally available inhibitor of Pim kinase with IC50 of 0.8, 5.1 and 1.8 nM for Pim1, 2 and 3, respectively. |
|
| DC12322 |
Papain |
Papain is a cysteine protease of the peptidase C1 family, which is used in food, pharmaceutical, textile, and cosmetic industries. |
|
| DC23618 |
PAPTP |
PAPTP is a PAP-1 derivative, potent, specific Kv1.3 channel inhibitor with IC50 of 31 nM in Jurkat T lymphocytes by patch-clamp, reduces cell viability and efficiently kills B16F10 cancer cells at 1 uM. |
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