DC23693 |
PDE10A-IN-31 |
PDE10A-IN-31 is a potent, highly selective PDE10A inhibitor with IC50 of 2 nM for both rPDE10A and hPDE10A. |
|
DC23701 |
PDE10A-IN-32 |
PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM).. |
|
DC12555 |
PDE2 inhibitor 4 |
PDE2 inhibitor 4 is a potent, selective, orally available inhibitor of PDE2 with IC50 of 2 nM, displays high selectivity versus other PDE isoforms. |
|
DC23698 |
PDE4D-IN-26b |
PDE4D-IN-26b is a potent, highly selective PDE4D inhibitor with IC50 of 0.6 nM, displays 75-fold lower activity against the PDE4A, B, and C subtypes, also exhibits 18,000-fold decreased potency against other PDE family members. |
|
DC23807 |
PDEδ-IN-99 |
PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ with Kd of 8±4 nM.. |
|
DC20047 |
PDGFRα kinase inhibitor 1 |
PDGFRα kinase inhibitor 1 is a highly selective type II PDGFRα kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively. |
|
DC10904 |
PDM2
Featured
|
PDM 2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM. |
|
DCAPI1314 |
Pefloxacin mesylate |
Pefloxacin mesylate |
|
DCAPI1528 |
Pemetrexed Disodium Hemipentahydrate
Featured
|
Pemetrexed Disodium Hemipentahydrate |
|
DC12178 |
Pemigatinib
Featured
|
Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma. |
|
DCAPI1224 |
Penicillamine (Cuprimine) |
Penicillamine (Cuprimine) |
|
DC10507 |
Pentamidine dihydrochloride
Featured
|
Pentamidine Dihydrochloride(MP601205 dihydrochloride) is an antimicrobial agent. |
|
DC7041 |
Pentostatin(Deoxycoformycin)
Featured
|
Pentostatin(Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). |
|
DC12194 |
PEO-IAA
Featured
|
PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs). |
|
DC12301 |
Pepstatin Ammonium (Pepstatin A Ammonium) |
Pepstatin Ammonium is a specific aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and he |
|
DC20494 |
Peptide Fz7-21 |
Peptide Fz7-21 is a potent, selective peptide inhibitor of Frizzled 7 receptor, inhibits exogenous WNT3A stimulated Wnt-β-catenin signaling in HEK293 cells with IC50 of 100 nM. |
|
DC21021 |
Peptide P60
Featured
|
Peptide P60 (FOXP3 inhibitor P60) is a 15-mer synthetic peptide, cell-permeable inhibitor of FOXP3, binds specifically to FOXP3; inhibits murine and human-derived Treg and improves effector T cell stimulation, overcomes the inhibitory effect of FOXP3 on the activity of the transcription factors NF-κB and NFAT, inhibits upregulation of mRNA for Foxp3 and IL-10 on effector T cells and enhances mRNA for IFN-γ after anti-CD3 stimulation; induces a scurfy-like disease in newborn mice, improves vaccine efficacy in mice model of CT26 tumor and HCV infection. |
|
DC20495 |
Perhexiline |
Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
|
DC21821 |
Perhexiline maleate
Featured
|
Perhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
|
DC9143 |
Perindopril erbumine |
Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease. |
|
DC12139 |
Perisesaccharide B |
Perisesaccharide B is an oligosaccharide isolated from the root barks of Periploca sepium. |
|
DC12137 |
Perisesaccharide C |
Perisesaccharide C is an oligosaccharide isolated from the root barks of Periploca sepium. |
|
DC20708 |
Perlapine |
Perlapine (AW-14233. |
|
DC12059 |
Pertussis Toxin
Featured
|
Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. |
|
DC12207 |
Petroselinic acid |
Petroselinic acid, a positional isomer of oleic acid, is isolated from the vegetable oil of Coriandrum sativum fruits. |
|
DC12192 |
PF 03709270 (ulopenem etzadroxil) |
PF 03709270 is an orally available ester prodrug form of sulopenem, with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria. |
|
DC22930 |
PF-4878691 (3M-852A)
Featured
|
PF 04878691 (PF 4878691, S 32865, 852A, 3M 001) is a selective TLR7 agonist that potently induces IFN-α and IFN-regulated proteins from human PBMC. |
|
DC8147 |
PF 4800567 |
PF 4800567 is a selective casein kinase 1ε inhibitor; displays 22-fold greater potency towards CK1ε than CK1δ (IC50 values are 32 and 711 nM for CK1ε and CK1δ respectively). |
|
DC21516 |
PF 5212372 |
PF 5212372 (PLA-950, ZPL-521, ZPL 5212372) is a potent, selective inhibitor of cPLA2 (cytosolic phospholipase A2α) with IC50 of 7 nM. |
|
DC21477 |
PF 6260933 dihydrochloride
Featured
|
PF 6260933 is a potent, selective and orally bioavailable MAP4K4 inhibitor with kinase IC50 of 3.7 nM, cell IC50 of 160 nM. |
|