| DC9027 |
Probenecid |
Probenecid inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. |
|
| DCAPI1123 |
Probucol |
Probucol |
|
| DC9008 |
Procarbazine HCl |
Procarbazine Hcl, an antineoplastic chemotherapy drug, is an alkylating agent for the treatment of Hodgkin's lymphoma and certain brain cancers; also inhibits MAO thus increasing the effects of sympathomimetics, TCAs, and tyramine. |
|
| DC23308 |
Procaspase-3 activator 1541 |
Procaspase-3 activator 1541 is a small-molecule inducer of cell death that noncovalently self-assembles into chemical fibrils and activates procaspase-3 and 6 in vitro (EC50=2.4 and 2.8 uM). |
|
| DC23307 |
Procaspase-3 activator 1541B |
Procaspase-3 activator 1541B is a specific, small molecule activator of procaspases-3 with EC50 of 1.3 uM. |
|
| DC25055 |
Prodigiosin
Featured
|
Prodigiosin is a natural red pigment produced by numerous bacterial species, has exhibited promising anticancer activity. |
|
| DC20192 |
Proflavine;3,6-Diaminoacridine |
Proflavine is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings. |
|
| DC10397 |
Proguanil
Featured
|
Proguanil is an antimalarial prodrug that is metabolized to the active metabolite cycloguanil, a dihydrofolate reductase (DHFR) inhibitor. |
|
| DCAPI1532 |
Promestriene |
Promestriene |
|
| DC20511 |
proMMP9-IN-3c |
proMMP9-IN-3c is a potent and specific inhibitor of the hemopexin-like domain of MMP-9 (proMMP-9) with Kd of 320 nM. |
|
| DC7476 |
P7C3
Featured
|
Proneurogenic, neuroprotective compound. Protects newborn neurons in the dentate gyrus and stimulates the growth of new neurons. Also enhances learning and memory in aged rats. Orally available and brain penetrant. |
|
| DC8670 |
Propanil |
Propanil is a widely used contact herbicide, mainly use in rice production. |
|
| DC12210 |
Propionylcarnitine |
Propionylcarnitine is a propionyl ester of L-carnitine. |
|
| DCAPI1212 |
Propylthiouracil |
Propylthiouracil |
|
| DC12171 |
PROTAC Linker 2 |
PROTAC Linker 2 is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand. |
|
| DC12264 |
Protac linker 5 |
Protac Linker 5 is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand. |
|
| DC20512 |
VHL ligand 1
Featured
|
PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.. |
|
| DC21535 |
proTAME |
proTAME is a cell permeable prodrug of TAME, which is an anaphase-promoting complex/cyclosome (APC/C) inhibitor that binds to the APC preferentially suppresses APC/C(Cdc20). |
|
| DC6903 |
Lapaquistat Acetate (TAK-475) |
Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs. |
|
| DC10241 |
Protirelin
Featured
|
Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin. |
|
| DC23021 |
Protodioscin
Featured
|
Protodioscin has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties. |
|
| DC20172 |
Proxyphylline; Monophylline, Spasmolysin |
Proxyphylline is a derivative of theophylline which is used as a bronchodilator and for its cardiovascular properties. It selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain) versus A2 adenosine receptors (Ki = 850 µM for platelets |
|
| DC7254 |
PRT062607 |
PRT062607(P505-15) anti-SYK activity is at least 80-fold greater than its affinity For other kinases. at least 80-fold greater than its affinity For other kinases. PRT062607 potently inhibits B cell antigen receptor-mediated B cell signaling and activation (IC50 0.27 and 0.28 μM, respectively) and Fcε receptor 1-mediated basophil degranulation (IC50 0.15 μM). PRT062607 inhibits BCR-dependent secretion of the chemokines CCL3 and CCL4 by CLL cells, and leukemia cell migration toward the tissue homing chemokines CXCL12, CXCL13, and beneath stromal cells. PRT062607 furthermore inhibits Syk and extracellular signal-regulated kinase phosphorylation after BCR triggering. For the detailed information of PRT062607, the solubility of PRT062607 in water, the solubility of PRT062607 in DMSO, the solubility of PRT062607 in PBS buffer, the animal experiment (test) of PRT062607, the cell expriment (test) of PRT062607, the in vivo, in vitro and clinical trial test of PRT062607, the EC50, IC50,and Affinity of PRT062607, Please contact DC Chemicals.. |
|
| DC21536 |
PS210
Featured
|
PS 210 is a potent, specific activator of PDK1 that target the PIF-binding pocket of PDK1, does not alter the activity of any of the 121 kinases (S6K, PKB/Akt or GSK3).. |
|
| DC21537 |
PS 423 |
PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210. |
|
| DC23286 |
PS1 |
PS1 is a potent inhibitor of IAP family with IC50 of 36/96/33 nM for c-IAP1/c-IAP2/XIAP respectively.. |
|
| DC21468 |
PS10 |
PS10 (PDK inhibitor PS10) is a novel potent and highly selective pyruvate dehydrogenase kinase (PDK) inhibitor. |
|
| DC23838 |
PS-432 |
PS-432 is an allosteric inhibitor of PKCι and PKCζ with IC50 of 16.9 and 18.5 uM, respectively. |
|
| DC22313 |
PS48
Featured
|
PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. |
|
| DC21538 |
PSB-12379 disodium |
PSB-12379 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.03/2.21 nM for rat/human recombinant eN. |
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