DC21539 |
PSB-12431 |
PSB-12431 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.2 nM for rat recombinant eN. |
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DC21540 |
PSB-12553 |
PSB-12553 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.5 nM for rat recombinant eN. |
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DCAPI1432 |
Mupirocin |
Pseudomonic Acid, also known as mupirocin, is an antibiotic isolated from Pseudomonas fluorescens which strongly inhibits protein and RNA synthesis. Inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit isole |
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DC6309 |
PSI6206
Featured
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PSI-6206 is a selective inhibitor of hepatitis C virus (HCV). |
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DC10162 |
PSI-7409 |
PSI-7409 is the active 5′-triphosphate metabolite of PSI-7851. PSI-7851 is a selective and highly active nucleotide analog inhibitor of HCV. |
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DC6308 |
Sofosbuvir(PSI7977,GS-7977)
Featured
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PSI-7977 is an investigational nucleotide analog currently in Phase 2 for treatment of chronic HCV infection. |
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DC7893 |
PSN632408 |
PSN632408 is an optimized agonist of GPR119 receptors that shows similar potency to OEA at both recombinant mouse and human GPR119 receptors, exhibiting EC50 values of 5.6 and 7.9 uM, respectively. |
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DC23683 |
PSN-GK1 |
PSN-GK1 is a potent, orally available Glucokinase (GK) activator with EC50 of 130 nM at 5 mM glucose (4.3-fold). |
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DC23654 |
Psora-4
Featured
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Psora-4 is a potent and selective Kv1.3 potassium channel blocker with EC50 of 3 nM. |
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DC23199 |
Psoralidin
Featured
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Psoralidin possesses potent antidepressant-like, anti-inflammatory, anticancer and chemopreventive properties. Psoralidin is a dual inhibitor of COX-2 and 5-LOX |
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DC20513 |
PST-1 |
PST-1 is a photoswitchable inhibitor of microtubule with EC50 of 0.5 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines. |
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DC20514 |
PST-1P |
PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines. |
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DC2005 |
PTC124 (Ataluren)
Featured
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PTC124 (Ataluren) is a potent nonsense mutation inhibitor with EC50 of ~0.1 μM. |
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DC7485 |
PTC-209
Featured
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PTC-209 is a specific inhibitor for BMI-1 with IC50 of 0.5 uM in in both GEMS reporter and ELISA assays. |
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DC8495 |
PTC-209 hydrobromide
Featured
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PTC-209 is a specific inhibitor for BMI-1 with IC50 of 0.5 uM in in both GEMS reporter and ELISA assays. |
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DC12482 |
PTC299
Featured
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PTC299 (PTC-299) is a novel potent inhibitor of dihydroorotate dehydrogenase (DHODH), inhibits hypoxia-induced VEGFA protein production in HeLa cells with IC50 of 1.64 nM. |
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DC21543 |
PTC725 |
PTC725 is a potent, selective, and orally bioavailable inhibitor of HCV NS4B, inhibits HCV 1b (Con1) replicons with EC50 of 1.7 nM. |
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DC20592 |
Pterosin B |
Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain. |
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DC20516 |
PTGR2-IN-22 |
PTGR2-IN-22 is a potent PTGR2 ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells. |
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DC10333 |
PTP1B-IN-2
Featured
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PTP1B-IN-2 is a novel protein tyrosine phosphatase-1B (PTP1B) inhibitor. |
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DC20517 |
PTP1B-IN-5b |
PTP1B-IN-5b is a potent protein tyrosine phosphatase PTP1B inhibitor with IC50 of 5.25 uM. |
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DC20518 |
PTUPB |
PTUPB is a novel dual acting COX-2/sEH inhibitor with IC50 of 1.26 uM/0.9 nM,does not inhibits COX-1 (IC50>100 uM). |
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DC8129 |
PTZ-343
Featured
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PTZ-343 is a phenothiazine derivative with chemical name: sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. |
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DC23354 |
PU-139 |
PU-139 is a potent, unselective HAT (Histone acetyltransferase) inhibitor that blocks the HATs Gcn5, p300/CBP-associated factor (PCAF), CREB protein (CBP) and p300. |
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DC23363 |
PU-141 |
PU-141 is a potent, selective CBP/p300 inhibitor that inhibits SK-N-SH cell growth with GI50 of 0.48 uM. |
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DC9919 |
Pulchinenoside A |
Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice. |
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DC9911 |
Pulsatilla saponin D(SB365) |
Pulsatilla saponin D(SB365) isolated from the root of Pulsatilla koreana, has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer. |
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DC23274 |
Purfalcamine
Featured
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Purfalcamine is a potent, specific inhibitor of Plaasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) with IC50 of 17 nM. |
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DCZ-287 |
Protopine |
purity >98%,Standard References |
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DCZ-284 |
Allosecurinine |
Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from Phyllanthus glaucus . |
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