Home > Inhibitors & Agonists > Others > Other Targets
Cat. No. Product name CAS No.
DC21899 Fadaltran

Fadaltran is a α2-adrenoreceptor antagonist..

1799809-36-1
DC21900 FAK inhibitor 5

FAK inhibitor 5 is the first highly potent, selective irreversible inhibitor of the FAK kinase with IC50 of 0.6 nM.

2237234-47-6
DCAPI1576 Falecalcitriol

Falecalcitriol

83805-11-2
DC21650 Famitinib

Famitinib (SHR1020) is a structural analogue of sunitinib, novel and potent multi-targeted RTK inhibitor, including c-Kit, VEGFR2/3, PDGFRβ, FLT-1/3 receptor and c-RET.

945380-27-8
DC10910 Fantofarone Featured

Fantofarone is a calcium channel blocker.

114432-13-2
DC20380 Faropenem

Faropenem is an orally active beta-lactam antibiotic with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes.

106560-14-9
DC24118 C75 Featured

C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).

218137-86-1
DC20381 Fasentin Featured

Fasentin is a novel inhibitor of glucose uptake (GLUT) that sensitizes cancer cells to FAS-induced cell death, preferentially inhibits GLUT4 (IC50=68 uM) over GLUT1.

392721-37-8
DC22759 FAS-IN-1

FAS-IN-1 is a potent inhibitor of fatty acid synthase (FAS) wtih IC50 of 10 nM..

1375105-96-6
DC10403 FAS-IN-1 Tosylate

FAS-IN-1 tosylate is a potent inhibitor of fatty acid synthase (FAS) extracted from patent WO 2012064642 A1, compound 29; has an IC50 of 10 nM.

DC10213 Fatostatin Featured

Fatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.

298197-04-3
DC23119 FB23-2(FTO Demethylase inhibitor FB23-2) Featured

FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM.

2243736-45-8
DC23507 FC131 Featured

FC131 (cyclo(-D-Tyr-Arg-Arg-Nal-Gly-)) is a selective, cyclopentapeptide CXCR4 antagonist with IC50 of 126 nM, exhibits anti-HIV activity in assays using NL4-3 and IIIB strains with EC50 of 21 nM..

606968-52-9
DC9753 FCCP Featured

FCCP is a very potent uncoupler of oxidative phosphorylation in mitochondria,that disrupts ATP synthesis by transporting protons across cell membranes.

370-86-5
DC23678 FCPR03

FCPR03 is a novel potent, selective PDE4 inhibitor with IC50 of 60, 31 and 47 nM for PDE4CAT (PDE4 catalytic domain), PDE4B1 and PDE4D7, respectively.

1917347-65-9
DC25015 FD-44

FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model.

68207-21-6
DC26037 FDL-169 Featured

FDL-169 is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector being developed by Flatley Discovery Lab for treating cystic fibrosis (CF) patients who carry the F508del mutation

1628416-28-3
DCAPI1591 FEBUXOSTAT Featured

FEBUXOSTAT is an inhibitor xanthine oxidase and xanthine dehydrogenase

144060-53-7
DC5099 Felbamate Featured

Felbamate (Felbatol) is an anticonvulsant drug used in the treatment of epilepsy.

25451-15-4
DC9105 Felodipine

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker.

72509-76-3
DC20382 FEN1-IN-1

FEN1-IN-1 is a potent, selective Flap Endonuclease-1 (FEN1) inhibitor with IC50 of 11 nM.

824983-91-7
DC20383 FEN1-IN-C20

FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM.

824983-94-0
DCAPI1181 Fenbendazole (Panacur)

Fenbendazole (Panacur)

43210-67-9
DC9065 Fenofibric acid

Fenofibric acid is a lipid regulating agent available as delayed release capsules for oral administration.

42017-89-0
DC9424 Fenoldopam (mesylate) Featured

Fenoldopam(SKF 82526) mesylate is a drug and synthetic benzazepine derivative which acts as a selective D1 receptor partial agonist.

67227-57-0
DCAPI1157 Fenoprofen calcium

Fenoprofen calcium

34597-40-5
DC8684 Fenoxaprop-P-ethyl Featured

Fenoxaprop-P-ethyl is a post-emergent phenoxy herbicide of the aryloxyphenoxy propionate group.

71283-80-2
DCAPI1326 Fenticonazole nitrate

Fenticonazole nitrate

73151-29-8
DC12246 Feretoside

Feretoside, a phenolic compound extracted from the barks of E. ulmoides, is a HSP inducer which act as cytoprotective agent.

27530-67-2
DC20102 Ferulic acid methyl ester Featured

Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical s

2309-07-1
DC23516 Fesoterodine

Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.

286930-02-7
DC23515 Fesoterodine maleate

Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.

250214-44-9
DC7811 Fexinidazole Featured

Fexinidazole is a new Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness

59729-37-2
DC21010 FF-10501-01

FF-10501-01 is a potent, selective and orally available IMPDH inhibitor.

56973-26-3
DC10973 FF-10502

FF-10502 (FF-10502-01) is a pyrimidine nucleoside antimetabolite that shows growth inhibition of pancreatic cancer cell lines with IC50 of 60-330 nM.

184302-49-6
DC23627 FFN-206 dihydrochloride

FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling

1883548-88-6
DC21012 FGI-103

FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).

907169-69-1
DC21013 FGI-104

FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).

DC7637 FH1(BRD-K4477) Featured

FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

2719-05-3
DC20384 Fhit-IN-15

Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells..

683784-49-8
DC20385 FICZ Featured

FICZ is a high affinity aryl hydrocarbon receptor (AhR) agonist with Kd of 70 pM.

172922-91-7
DC21673 Fidarestat

Fidarestat (SNK860) is a potent aldose reductase inhibitor, improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats..

136087-85-9
DC21817 Filaminast

Filaminast (WAY-PDA-641.

141184-34-1
DC21482 Filibuvir

Filibuvir (PF-00868554.

877130-28-4
DC9349 Fimasartan Featured

Fimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure.

247257-48-3
DC11432 FimH inhibitor 5h

FimH inhibitor 5h is a potent and orally active FimH inhibitor.

2240179-36-4
DC23501 Finazine

Finazine is a high-affinity, brain penetrant sigma-1 and sigma 2 receptor ligand with Ki of 2.6 nM and 46 nM, respectively.

441745-52-4
DC12637 Finerenone Featured

Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.

1050477-31-0
DC8200 Firategrast(SB-683699) Featured

Firategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS).

402567-16-2
DC21015 FIT-039 Featured

FIT-039 is a potent, selective CDK9 inhibitor with IC50 of 5.8 uM for CKD9/cyclin T1, suppresses the replication of HSV-1 (IC50=0.69 uM).

1113044-49-7
DC9845 FITM Featured

FITM is a nove mGlu1 inhibitor. FITM shows high affinity (Ki = 2.5 nM, fig. S2) and selectivity for mGlu1 over mGlu5.

932737-65-0
DC20386 Pioglitazone Featured

Pioglitazone is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.

111025-46-8
DC21016 FJ 5002

FJ 5002 is a potent telomerase inhibitor with IC50 of 2 uM, a close derivative of MKT077.

247129-77-7
DC22093 FKGK18

FKGK18 (FKGK18) is a potent, selective inhibitor of iPLA2 (group VIA Ca2+-independent phospholipase A2) with IC50 of 50 nM.

1071001-09-6
DC20019 Flagelin 22(TFA) (Flagellin 22(TFA))

Flagelin 22 TFA, a fragment of bacterial flagellin, is an effective elicitor in both plants and algae.

DC11414 Flavoxate Hydrochloride Featured

Flavoxate Hydrochloride(DW-61 Hydrochloride) is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic.

3717-88-2
DCAPI1347 Fleroxacin (Quinodis)

Fleroxacin (Quinodis)

79660-72-3
DC7415 FLI-06 Featured

FLI-06 is a novel potent and selective small molecule intercepting Notch signaling and the early secretory pathway (EC50 ~2.3 μM).

313967-18-9
DC9321 Flibanserin Featured

Flibanserin is a novel multifunctional serotonin agonist and antagonist (MSAA) that improves sexual functioning in premenopausal women who suffer from reduced sexual interest and desire.

167933-07-5
DC8230 FLT3-IN-1(SKLB4771) Featured

FLT3-IN-1(SKLB4771) is a novel potent and selective Flt3 inhibitor with IC50 of 10 nM; against FLT3-ITD-expressing MV4-11 cells with IC50 of 6 nM.

1370256-78-2
DC9060 Flubendazole

Flubendazole is a potent broad spectrum anthelmintic.

31430-15-6
DCAPI1375 Fluconazole

Fluconazole

86386-73-4
DCAPI1108 Flucytosine (Ancobon)

Flucytosine (5-Fluorocytosine, 5-FC, Ancobon) is an antifungal drug with IC50 of 0.12 μg/mL in C.albicans.

2022-85-7
DC5889 Fludarabine Featured

Fludarabine (Synonyms: F-ara-A; NSC 118218) is a prodrug converted to free nucleoside 9-β-D-arabinosyl-2-fluoroadenine (F-ara-A). F-ara-A enters cells and accumulates as 5’-triphosphate. Interferes with DNA synthesis and repair.

21679-14-1
DC4190 Fludarabine phosphate Featured

Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.

75607-67-9
DC8337 Fluensulfone Featured

Fluensulfone is a new nematicide of the fluoroalkenyl thioether group that has significantly reduced environmental impact with low toxicity to non-target insects and mammals.

318290-98-1
DC11413 Flumatinib Featured

Flumatinib is a multi-kinase inhibitor with IC50 Values of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRβ and c-Kit respectively.

895519-90-1
DCAPI1180 Flumequine

Flumequine

42835-25-6
DC8910 Flunarizine dihydrochloride Featured

Flunarizine is a selective calcium entry blocker.

30484-77-6
DCAPI1301 Fluocinolone acetonide (Flucort-N)

Fluocinolone acetonide (Flucort-N)

67-73-2
DCAPI1161 Fluocinonide(Vanos)

Fluocinonide(Vanos)

356-12-7
DC22475 FITC Featured

Fluorescein isothiocyanate(FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry.

3326-32-7
DC10424 Fluorescein-5-maleimide Featured

Fluorescein-5-maleimide is a fluorescent thiol-reactive dye used to conjugate fluorescein to proteins (excitation: 494 nm, emission: 519 nm).

75350-46-8
DC9669 Fluoroclebopride Featured

Fluoroclebopride is useful chemical for PET image study.

154540-49-5
DC10238 Fluoxymesterone

Fluoxymesterone is an Androgen. The mechanism of action of fluoxymesterone is as an Androgen Receptor Agonist.

76-43-7
DC12247 Fluspirilene (R 6218; Redeptin) Featured

Fluspirilene is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM. Fluspirileneis a long-acting injectable depot antipsychotic drug used for schizophrenia.

1841-19-6
DC10020 Fluticasone furoate Featured

Fluticasone furoate is a synthetic trifluorinated corticosteroid with potent anti-inflammatory activity.

397864-44-7
DC10678 Fluticasone Featured

Fluticasone is a synthetic glucocorticoid which is used in some countries to treat nasal symptoms.

90566-53-3
DCAPI1353 Fluticasone propionate (Flonase, Veramyst)

Fluticasone propionate (Flonase, Veramyst)

80474-14-2
DCAPI1585 Fluyastatin Sodium Salt

Fluvastatin, Sodium Salt is a synthetic inhibitor of HMGCR (HMG-CoA reductase) (IC50 = 40-100 nM for human liver microsomes) that acts as an anti-hypercholesterolemic compound and as an antioxidant. Fluvastatin also inhibits induction of the LDL receptor

93957-55-2
DC9139 Fluvoxamine maleate

Fluvoxamine maleate is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.

61718-82-9
DC22228 Fluzoparib Featured

Fluzoparib (SHR 3162) is a selective poly [ADP-ribose] polymerase 1 (PARP1) and poly [ADP-ribose] polymerase 2 inhibitor (PARP2), being developed by Jiangsu HengRui Medicine, for the treatment of cancer. PARP enzymes play a vital role in repair of DNA dam

1358715-18-0
DC26027 FMF-04-159-2 Featured

FMF-04-159-2 is a covalent CDK14 inhibitor. FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively.

2364489-81-4
DC21018 FN075

FN075 is a small-molecule inhibitor targeting Escherichia coli amyloid biogenesis and biofilm formation.

864405-82-3
DC21019 FOBISIN 101 Featured

FOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively.

1370281-06-3
DC10252 Fomepizole

Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.

7554-65-6
DC4207 Fondaparinux sodium Featured

Fondaparinux sodium is a synthetic and specific inhibitor of activated Factor X (Xa).

114870-03-0
DCAPI1249 Acesulfame Potassium Featured

Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice.

55589-62-3
DC8285 Acotiamide HCl Featured

Acotiamide monohydrochloride trihydrate is an orally active and first-in-class gastroprokinetic agent for the treatment of functional dyspepsia. Acotiamide monohydrochloride trihydrate enhances acetylcholine released by enteric neurons through muscarinic

773092-05-0
DC8204 AS2034178,

For the detailed information of AS-2034178,AS 2034178, the solubility of AS-2034178,AS 2034178 in water, the solubility of AS-2034178,AS 2034178 in DMSO, the solubility of AS-2034178,AS 2034178 in PBS buffer, the animal experiment (test) of AS-2034178,AS 2034178, the cell expriment (test) of AS-2034178,AS 2034178, the in vivo, in vitro and clinical trial test of AS-2034178,AS 2034178, the EC50, IC50,and affinity,of AS-2034178,AS 2034178, For the detailed information of AS-2034178,AS 2034178, the solubility of AS-2034178,AS 2034178 in water, the solubility of AS-2034178,AS 2034178 in DMSO, the solubility of AS-2034178,AS 2034178 in PBS buffer, the animal experiment (test) of AS-2034178,AS 2034178, the cell expriment (test) of AS-2034178,AS 2034178, the in vivo, in vitro and clinical trial test of AS-2034178,AS 2034178, the EC50, IC50,and affinity,of AS-2034178,AS 2034178, Please contact DC Chemicals..

1030846-42-4
DC7870 BBS-4

For the detailed information of BBS-4, the solubility of BBS-4 in water, the solubility of BBS-4 in DMSO, the solubility of BBS-4 in PBS buffer, the animal experiment (test) of BBS-4, the cell expriment (test) of BBS-4, the in vivo, in vitro and clinical trial test of BBS-4, the EC50, IC50,and affinity,of BBS-4, Please contact DC Chemicals..

402934-09-2
DCAPI1114 Betamethasone valerate (Betnovate)

For the detailed information of Betamethasone valerate (Betnovate), the solubility of Betamethasone valerate (Betnovate) in water, the solubility of Betamethasone valerate (Betnovate) in DMSO, the solubility of Betamethasone valerate (Betnovate) in PBS buffer, the animal experiment(test) (test) of Betamethasone valerate (Betnovate), the cell expriment (test) of Betamethasone valerate (Betnovate), the in vivo, in vitro and clinical trial test of Betamethasone valerate (Betnovate), the EC50, IC50,and Affinity of Betamethasone valerate (Betnovate),, please contact DC Chemicals..

2152-44-5
DC8046 BIO-32546

For the detailed information of BIO-32546, the solubility of BIO-32546 in water, the solubility of BIO-32546 in DMSO, the solubility of BIO-32546 in PBS buffer, the animal experiment (test) of BIO-32546, the cell expriment (test) of BIO-32546, the in vivo, in vitro and clinical trial test of BIO-32546, the EC50, IC50,and affinity,of BIO-32546, For the detailed information of BIO-32546, the solubility of BIO-32546 in water, the solubility of BIO-32546 in DMSO, the solubility of BIO-32546 in PBS buffer, the animal experiment (test) of BIO-32546, the cell expriment (test) of BIO-32546, the in vivo, in vitro and clinical trial test of BIO-32546, the EC50, IC50,and affinity,of BIO-32546, Please contact DC Chemicals..

1548743-66-3
DCAPI1083 Dimesna

For the detailed information of Dimesna, the solubility of Dimesna in water, the solubility of Dimesna in DMSO, the solubility of Dimesna in PBS buffer, the animal experiment(test) (test) of Dimesna, the cell expriment (test) of Dimesna, the in vivo, in vitro and clinical trial test of Dimesna, the EC50, IC50,and Affinity of Dimesna,, please contact DC Chemicals..

16208-51-8
DC7849 DTP3 Featured

For the detailed information of DTP3, the solubility of DTP3 in water, the solubility of DTP3 in DMSO, the solubility of DTP3 in PBS buffer, the animal experiment (test) of DTP3, the cell expriment (test) of DTP3, the in vivo, in vitro and clinical trial test of DTP3, the EC50, IC50,and affinity,of DTP3, Please contact DC Chemicals..

1809784-29-9
DC7013 Epothilone F

For the detailed information of Epothilone F, the solubility of Epothilone F in water, the solubility of Epothilone F in DMSO, the solubility of Epothilone F in PBS buffer, the animal experiment (test) of Epothilone F, the cell expriment (test) of Epothilone F, the in vivo, in vitro and clinical trial test of Epothilone F, the EC50, IC50,and Affinity of Epothilone F, Please contact DC Chemicals..

208518-52-9
DC8367 IN00076730

For the detailed information of IN00076730, the solubility of IN00076730 in water, the solubility of IN00076730 in DMSO, the solubility of IN00076730 in PBS buffer, the animal experiment (test) of IN00076730, the cell expriment (test) of IN00076730, the in vivo, in vitro and clinical trial test of IN00076730, the EC50, IC50,and affinity,of IN00076730, For the detailed information of IN00076730, the solubility of IN00076730 in water, the solubility of IN00076730 in DMSO, the solubility of IN00076730 in PBS buffer, the animal experiment (test) of IN00076730, the cell expriment (test) of IN00076730, the in vivo, in vitro and clinical trial test of IN00076730, the EC50, IC50,and affinity,of IN00076730, Please contact DC Chemicals..

1454700-89-0
DC7017 KF-4317

For the detailed information of KF-4317, the solubility of KF-4317 in water, the solubility of KF-4317 in DMSO, the solubility of KF-4317 in PBS buffer, the animal experiment (test) of KF-4317, the cell expriment (test) of KF-4317, the in vivo, in vitro and clinical trial test of KF-4317, the EC50, IC50,and Affinity of KF-4317, Please contact DC Chemicals..

76805-48-6
DC7546 LHW090-A7 Featured

For the detailed information of LHW090-A7, the solubility of LHW090-A7 in water, the solubility of LHW090-A7 in DMSO, the solubility of LHW090-A7 in PBS buffer, the animal experiment (test) of LHW090-A7, the cell expriment (test) of LHW090-A7, the in viv

1308256-94-1
DC7580 Naxagolide Featured

For the detailed information of Naxagolide, the solubility of Naxagolide in water, the solubility of Naxagolide in DMSO, the solubility of Naxagolide in PBS buffer, the animal experiment (test) of Naxagolide, the cell expriment (test) of Naxagolide, the in vivo, in vitro and clinical trial test of Naxagolide, the EC50, IC50,and Affinity of Naxagolide, Please contact DC Chemicals..

88058-88-2
DC7618 NI-(S)-BPB-GLY Featured

For the detailed information of NI-(S)-BPB-GLY, the solubility of NI-(S)-BPB-GLY in water, the solubility of NI-(S)-BPB-GLY in DMSO, the solubility of NI-(S)-BPB-GLY in PBS buffer, the animal experiment (test) of NI-(S)-BPB-GLY, the cell expriment (test) of NI-(S)-BPB-GLY, the in vivo, in vitro and clinical trial test of NI-(S)-BPB-GLY, the EC50, IC50,and Affinity of NI-(S)-BPB-GLY, Please contact DC Chemicals..

96293-19-5
DC8441 Nitenpyram Featured

Nitenpyram is a chemical frequently used as an insecticide in agriculture and veterinary medicine. The compound is an insect neurotoxin belonging to the class of neonicotinoids which works by blocking neural signaling of the central nervous system.

150824-47-8
DC5110 NSC157100

For the detailed information of NSC157100, the solubility of NSC157100 in water, the solubility of NSC157100 in DMSO, the solubility of NSC157100 in PBS buffer, the animal experiment (test) of NSC157100, the cell expriment (test) of NSC157100, the in vivo, in vitro and clinical trial test of NSC157100, the EC50, IC50,and Affinity of NSC157100, Please contact DC Chemicals..

39204-49-4
DC7022 NSC17711

For the detailed information of NSC17711, the solubility of NSC17711 in water, the solubility of NSC17711 in DMSO, the solubility of NSC17711 in PBS buffer, the animal experiment (test) of NSC17711, the cell expriment (test) of NSC17711, the in vivo, in vitro and clinical trial test of NSC17711, the EC50, IC50,and Affinity of NSC17711, Please contact DC Chemicals..

1112-24-9
DC7024 Ospemifene

For the detailed information of Ospemifene, the solubility of Ospemifene in water, the solubility of Ospemifene in DMSO, the solubility of Ospemifene in PBS buffer, the animal experiment (test) of Ospemifene, the cell expriment (test) of Ospemifene, the in vivo, in vitro and clinical trial test of Ospemifene, the EC50, IC50,and Affinity of Ospemifene, Please contact DC Chemicals..

128607-22-7
DC7025 PB30239

For the detailed information of PB30239, the solubility of PB30239 in water, the solubility of PB30239 in DMSO, the solubility of PB30239 in PBS buffer, the animal experiment (test) of PB30239, the cell expriment (test) of PB30239, the in vivo, in vitro and clinical trial test of PB30239, the EC50, IC50,and Affinity of PB30239, Please contact DC Chemicals..

1251012-82-4
DC7551 RG3039(PF-06687859) Featured

For the detailed information of PF-0668759, the solubility of PF-0668759 in water, the solubility of PF-0668759 in DMSO, the solubility of PF-0668759 in PBS buffer, the animal experiment (test) of PF-0668759, the cell expriment (test) of PF-0668759, the

1005504-62-0
DC6915 Phenothrin

For the detailed information of Phenothrin, the solubility of Phenothrin in water, the solubility of Phenothrin in DMSO, the solubility of Phenothrin in PBS buffer, the animal experiment (test) of Phenothrin, the cell expriment (test) of Phenothrin, the in vivo, in vitro and clinical trial test of Phenothrin, the EC50, IC50,and affinity,of Phenothrin, For the detailed information of Phenothrin, the solubility of Phenothrin in water, the solubility of Phenothrin in DMSO, the solubility of Phenothrin in PBS buffer, the animal experiment (test) of Phenothrin, the cell expriment (test) of Phenothrin, the in vivo, in vitro and clinical trial test of Phenothrin, the EC50, IC50,and affinity,of Phenothrin, Please contact DC Chemicals..

26002-80-2
DC22285 praeruptorin B Featured

For the detailed information of praeruptorin B, the solubility of praeruptorin B in water, the solubility of praeruptorin B in DMSO, the solubility of praeruptorin B in PBS buffer, the animal experiment(test) (test) of praeruptorin B, the cell expriment (test) of praeruptorin B, the in vivo, in vitro and clinical trial test of praeruptorin B, the EC50, IC50,and Affinity of praeruptorin B,, please contact DC Chemicals..

73069-28-0
DC7844 PST2286

For the detailed information of PST2286, the solubility of PST2286 in water, the solubility of PST2286 in DMSO, the solubility of PST2286 in PBS buffer, the animal experiment (test) of PST2286, the cell expriment (test) of PST2286, the in vivo, in vitro and clinical trial test of PST2286, the EC50, IC50,and affinity,of PST2286, Please contact DC Chemicals..

26629-41-4
DCAPI1402 Reboxetine mesylate

For the detailed information of Reboxetine mesylate, the solubility of Reboxetine mesylate in water, the solubility of Reboxetine mesylate in DMSO, the solubility of Reboxetine mesylate in PBS buffer, the animal experiment(test) (test) of Reboxetine mesylate, the cell expriment (test) of Reboxetine mesylate, the in vivo, in vitro and clinical trial test of Reboxetine mesylate, the EC50, IC50,and Affinity of Reboxetine mesylate,, please contact DC Chemicals..

98769-84-7
DC7616 RO 15-3890 Featured

For the detailed information of RO 15-3890, the solubility of RO 15-3890 in water, the solubility of RO 15-3890 in DMSO, the solubility of RO 15-3890 in PBS buffer, the animal experiment (test) of RO 15-3890, the cell expriment (test) of RO 15-3890, the in vivo, in vitro and clinical trial test of RO 15-3890, the EC50, IC50,and Affinity of RO 15-3890, Please contact DC Chemicals..

84378-44-9
DC8209 SD-70 Featured

A small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program, in part by inhibition of the demethylase KDM4C (IC50=30 uM).

332173-89-4
DC8210 SKP2-C25

For the detailed information of SKP2-C25, the solubility of SKP2-C25 in water, the solubility of SKP2-C25 in DMSO, the solubility of SKP2-C25 in PBS buffer, the animal experiment (test) of SKP2-C25, the cell expriment (test) of SKP2-C25, the in vivo, in vitro and clinical trial test of SKP2-C25, the EC50, IC50,and affinity,of SKP2-C25, For the detailed information of SKP2-C25, the solubility of SKP2-C25 in water, the solubility of SKP2-C25 in DMSO, the solubility of SKP2-C25 in PBS buffer, the animal experiment (test) of SKP2-C25, the cell expriment (test) of SKP2-C25, the in vivo, in vitro and clinical trial test of SKP2-C25, the EC50, IC50,and affinity,of SKP2-C25, Please contact DC Chemicals..

DC7507 HIV-1 integrase inhibitor 8 Featured

HIV-1 integrase inhibitor 8 is a HIV-1 integrase inhibitor, compound 8[1].

1568-80-5
DC7032 SR03168

For the detailed information of SR03168, the solubility of SR03168 in water, the solubility of SR03168 in DMSO, the solubility of SR03168 in PBS buffer, the animal experiment (test) of SR03168, the cell expriment (test) of SR03168, the in vivo, in vitro and clinical trial test of SR03168, the EC50, IC50,and Affinity of SR03168, Please contact DC Chemicals..

484654-44-6
DC7033 SR03298A

For the detailed information of SR03298A, the solubility of SR03298A in water, the solubility of SR03298A in DMSO, the solubility of SR03298A in PBS buffer, the animal experiment (test) of SR03298A, the cell expriment (test) of SR03298A, the in vivo, in vitro and clinical trial test of SR03298A, the EC50, IC50,and Affinity of SR03298A, Please contact DC Chemicals..

805250-17-3
DC8211 SR10067

For the detailed information of SR10067, the solubility of SR10067 in water, the solubility of SR10067 in DMSO, the solubility of SR10067 in PBS buffer, the animal experiment (test) of SR10067, the cell expriment (test) of SR10067, the in vivo, in vitro and clinical trial test of SR10067, the EC50, IC50,and affinity,of SR10067, For the detailed information of SR10067, the solubility of SR10067 in water, the solubility of SR10067 in DMSO, the solubility of SR10067 in PBS buffer, the animal experiment (test) of SR10067, the cell expriment (test) of SR10067, the in vivo, in vitro and clinical trial test of SR10067, the EC50, IC50,and affinity,of SR10067, Please contact DC Chemicals..

1380548-02-6
DCAPI1260 Sulfamethazine

For the detailed information of Sulfamethazine, the solubility of Sulfamethazine in water, the solubility of Sulfamethazine in DMSO, the solubility of Sulfamethazine in PBS buffer, the animal experiment(test) (test) of Sulfamethazine, the cell expriment (test) of Sulfamethazine, the in vivo, in vitro and clinical trial test of Sulfamethazine, the EC50, IC50,and Affinity of Sulfamethazine,, please contact DC Chemicals..

57-68-1
DC7973 Tenovin-2 Featured

For the detailed information of Tenovin-2, the solubility of Tenovin-2 in water, the solubility of Tenovin-2 in DMSO, the solubility of Tenovin-2 in PBS buffer, the animal experiment (test) of Tenovin-2, the cell expriment (test) of Tenovin-2, the in vivo, in vitro and clinical trial test of Tenovin-2, the EC50, IC50,and affinity,of Tenovin-2, Please contact DC Chemicals..

666211-30-9
DC7974 Tenovin-5

For the detailed information of Tenovin-5, the solubility of Tenovin-5 in water, the solubility of Tenovin-5 in DMSO, the solubility of Tenovin-5 in PBS buffer, the animal experiment (test) of Tenovin-5, the cell expriment (test) of Tenovin-5, the in vivo, in vitro and clinical trial test of Tenovin-5, the EC50, IC50,and affinity,of Tenovin-5, Please contact DC Chemicals..

688014-33-7
DC8176 Tradipitant(VLY-686) Featured

For the detailed information of Tradipitant(VLY-686), the solubility of Tradipitant(VLY-686) in water, the solubility of Tradipitant(VLY-686) in DMSO, the solubility of Tradipitant(VLY-686) in PBS buffer, the animal experiment (test) of Tradipitant(VLY-686), the cell expriment (test) of Tradipitant(VLY-686), the in vivo, in vitro and clinical trial test of Tradipitant(VLY-686), the EC50, IC50,and affinity,of Tradipitant(VLY-686), For the detailed information of Tradipitant(VLY-686), the solubility of Tradipitant(VLY-686) in water, the solubility of Tradipitant(VLY-686) in DMSO, the solubility of Tradipitant(VLY-686) in PBS buffer, the animal experiment (test) of Tradipitant(VLY-686), the cell expriment (test) of Tradipitant(VLY-686), the in vivo, in vitro and clinical trial test of Tradipitant(VLY-686), the EC50, IC50,and affinity,of Tradipitant(VLY-686), Please contact DC Chemicals..

622370-35-8
DC6916 Zucapsaicin

For the detailed information of Zucapsaicin, the solubility of Zucapsaicin in water, the solubility of Zucapsaicin in DMSO, the solubility of Zucapsaicin in PBS buffer, the animal experiment (test) of Zucapsaicin, the cell expriment (test) of Zucapsaicin, the in vivo, in vitro and clinical trial test of Zucapsaicin, the EC50, IC50,and affinity,of Zucapsaicin, For the detailed information of Zucapsaicin, the solubility of Zucapsaicin in water, the solubility of Zucapsaicin in DMSO, the solubility of Zucapsaicin in PBS buffer, the animal experiment (test) of Zucapsaicin, the cell expriment (test) of Zucapsaicin, the in vivo, in vitro and clinical trial test of Zucapsaicin, the EC50, IC50,and affinity,of Zucapsaicin, Please contact DC Chemicals..

25775-90-0
DC9045 Formestane

Formestane(CGP-32349; 4-OHA) is a selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer.

566-48-3
DC1017 Forskolin Featured

Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC).

66575-29-9
DC10181 Forsythoside B

Forsythoside B is a phenylethanoid glycoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation.

81525-13-5
DC21472 Fosdagrocorat

Fosdagrocorat (PF 04171327) is an orally available, potential dissociated agonist of the glucocorticoid receptor (GR) for the treatment of rheumatoid arthritis, the phosphate ester prodrug of PF-00251802 (dagrocorat)..

1044535-58-1
DC11086 Foslinanib

Foslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities, induces cancer cell apoptosis and inhibits cancer cell proliferation.

1256037-60-1
DC12068 Fosmidomycin sodium salt Featured

Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial drug, which is active against both Gram-negative and Gram-positive bacteria.

66508-37-0
DC12063 Fosravuconazole

Fosravuconazole is a prodrug of ravuconazole, with antifungal activity.

351227-64-0
DC23114 R788 disodium hexahydrate Featured

Fostamatinib (R788) is a prodrug of the active metabolite R406, which is a potent, ATP-competitive inhibitor of Syk kinase with Ki/IC50 of 30/41 nM.

914295-16-2
DC12315 Fosteabine (Cytarabine ocfosfate; YNK 01)

Fosteabine is an oral and prodrug analogue of cytarabine which is resistant to deoxycytidine deaminase.

73532-83-9
DC10510 FPH1 (BRD-6125) Featured

FPH1 (BRD-6125) is a small molecule, which promotes expansion of iPS-derived hepatocytes.

708219-39-0
DC21023 FQI1

FQI1 is a small-molecule inhibitor of transcription factor LSF with IC50 of 2.1 uM.

599151-35-6
DC21024 FQI2

FQI2 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.71 uM.

1373209-41-6
DC21025 FR900098 sodium salt Featured

FR 900098 is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively..

73226-73-0
DC12242 FR194738

FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.

204067-52-7
DC12398 FR58P1a

FR58P1a is a mitochondrial metabolism-affecting compound that uncouples OXPHOS through a protonophoric mechanism, selectively inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway.

DC23729 FR-901464 Featured

FR-901464 is a potent antitumor natural product that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, inhibits cell cycle progression at G1 and G2/M phases..

146478-72-0
DC8631 Framycetin sulphate

Framycetin sulphate

4146-30-9
DC8003 FRAX-486 Featured

FRAX486 is a selective inhibitor of group I PAKs with IC50s of 8.25/39.5, /55.3 nM for PAK1/PAK2/PAK3 respectivelt; less potent for PAK4(IC50=779 nM).

1232030-35-1
DCQ-033 fraxin

Fraxin is a coumarin glycoside that has been found in Fraxinus and has anti-inflammatory activity.

524-30-1
DC23050 fraxinellone Featured

Fraxinellone is a selective blocker of voltage-dependent Ca2+ channel, which possesses antimicrobial, anti-inflammatory, neuroprotective and vasorelaxing activities.

28808-62-0
DC9344 Frentizole

Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.

26130-02-9
DC20208 Frovatriptan Succinate

Frovatriptan Succinate is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.

158930-09-7
DC21026 FSC 231

FSC 231 (FSC231) is the first, cell-permeable small-molecule inhibitor of PICK1 PDZ domain with Kd of 10.1 uM.

1215849-96-9
DC23388 FT-001

FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1.

1778655-51-8
DC20272 FT113 Featured

FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme.

1630808-89-7
DC22096 FT895

FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM).

2225728-57-2
DC11029 FTBMT Featured

FTBMT is a novel selective GPR52 agonist of GPR52, increases intracellular cAMP levels in CHO cells expressing human, mouse, or rat GPR52, with pEC50 of 7.03, 6.85, and 6.87M, respectively.

1358575-02-6
DC12537 FtsZ inhibitor C109

FtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2 uM.

DC12362 Fuchsine base monohydrochloride

Fuchsine base (monohydrochloride) is a magenta dye, which is certified for use for acid-fast staining with carbol-fuchsin.

632-99-5
DCAPI1052 Fudosteine

Fudosteine

13189-98-5
DC11394 Fulacimstat(BAY 1142524) Featured

Fulacimstat(BAY 1142524) is a small molecule chymase inhibitor.

1488354-15-9
DC4200 Fulvestrant Featured

Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.094 nM.

129453-61-8
DC8855 Fumagillin Featured

Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.

23110-15-8
DCAPI1020 Fumalic acid (Ferulic acid) Featured

Fumalic acid (Ferulic acid)

1135-24-6
DC21027 Fumosorinone

Fumosorinone is a novel potent, selective protein tyrosine phosphatase SHP2 inhibitor with IC50 of 6.31 uM.

1879030-70-2
DC9069 Furosemide

Furosemide (Lasix) is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.

54-31-9
DC10240 Fusidate Sodium

Fusidate Sodium is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.

751-94-0
DC21792 FV-100

FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro..

956483-03-7
DC21031 FzM1.8

FzM1.8 is a small molecule, allosteric agonist of the Frizzled receptor Fzd4 with pEC50 of 6.4, potentiates β-catenin pathway in the absence of any WNT ligand.

2204290-85-5
DC21032 G 0507

G 0507 is a novel inhibitor of the bacterial LolCDE ABC transporter, binds to LolCDE and stimulates its ATPase activity.

1223998-29-5
DC21034 G 573

G 573 is a potent and selective, allosteric inhibitor of MEK with Ki of 0.3 nM.

22868-35-5
DC11449 G0775

G0775 is a Synethetic analogs of arylomycins.

2098663-92-2
DC24027 STING Agonist-1(G-10) Featured

G10 (STING Agonist 1) is a novel human-specific STING agonist.

702662-50-8
DC12300 G3-C12 TFA

G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins.

DC22548 G-5555

G-5555 is a potent and selective PAK1 inhibitor (Ki=3.7 nM).

1648863-90-4
DC12438 G6PD activator AG1 Featured

G6PD activator AG1 (AG1) is a specific, small molecule that increases the activity of the wild-type, Canton mutant (R459L, EC50=3 uM) and several other common G6PD mutants; displays no effect on the dimerization or activity of several other NAD- or NADP+-dependent dimeric or tetrameric enzymes, including 6PGD, GAPDH, ALDH2, and ALDH3A1; attenuates ROS-induced pericardial edema in a G6PD-dependent manner in zebrafish, reduces hemolysis of human erythrocytes

421581-52-4
DC21035 G907

G907 is a potent, selective small-molecule antagonist of ATP-binding cassette (ABC) transporter MsbA with IC50 of 18 nM.

DC21036 E-72

G9a inhibitor E72 (E-72) is a potent inhibitor of histone H3K9 methyltransferases G9a and G9a-like protein (GLP) with Kd of 136 nM and 164 nM, shows selectivity over the related H3K9 methyltransferase Suv39H2.

1435055-73-4
DC9129 Gabexate mesylate

Gabexate Mesylate is a Factor X inhibitor.

56974-61-9
DCAPI1037 Gadodiamide (Omniscan) Featured

Gadodiamide is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Target: OthersGadodiamide(Omniscan) is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Gadodiamide is a contrast medium for cranial and spinal magnetic resonance imaging (MRI) and for general MRI of the body after intravenous administration. The product provides contrast enhancement and facilitates visualisation of abnormal structures or lesions in various parts of the body including the central nervous system (CNS). A recent review takes the question of toxicity caused by loss of gadolinium from the complex. "The challenge for nephrologists includes (a) evidence of transmetallation, such as gadolinium deposits in bone, increased urinary zinc excretion, iron-transferrin dissociation or 'spurious hypocalcemia' in exposed people"。

122795-43-1
DC11053 GAK inhibitor 49 Featured

GAK inhibitor 49 is a potent, selective, ATP-competitive inhibitor of cyclin G-associated kinase (GAK, cell IC50=56 nM) with favourable NAK family selectivity (AAK1, STK16, BMP2K).

319492-82-5
DC12228 Galactose 1-phosphate

Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars.

2255-14-3
DC12305 Galactose 1-phosphate Potassium salt

Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sugars

19046-60-7
DC21038 Galvestine-1

Galvestine-1 is a small molecule MGDG (monogalactosyldiacylglycerol) synthase inhibitor with IC50 of 10 uM by competing with diacylglycerol binding.

1087311-82-7
DC12090 Gamitrinib TPP

Gamitrinib TPP is a GA mitochondrial matrix inhibitor.

1131626-46-4
DC9640 gamma-secretase modulator 3

gamma-secretase modulator 3 is a gamma-secretase modulator.

1431697-84-5
DC21197 Ganaplacide Featured

Ganaplacide (KAF156, GNF-156) is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains.

1261113-96-5
DCAPI1357 Ganciclovir

Ganciclovir

82410-32-0
DC8877 Ganirelix Featured

Ganirelix is a man-made form of a protein that reduces the amount of certain hormones in the body, including estrogen.

124904-93-4
DC7129 GANT61(NSC 136476) Featured

GANT 61(NSC 136476) is a small molecule inhibitor of Gli1 and Gli2.

500579-04-4
DC20388 GAPDS Featured

GAPDS is a small molecule that targets the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH).

917773-99-0
DC23398 Garcinol

Garcinol (Camboginol) is a potent, natural inhibitor of histone acetyltransferases (HATs) p300 (IC50=7 uM) and PCAF (IC50=5 uM) both in vitro and in vivo.

78824-30-3
DC26031 Gardiquimod trifluoroacetate Featured

Gardiquimod trifluoroacetate is a specific TLR7 agonist which can also inhibit HIV-1 reverse transcriptase.

1159840-61-5
DC22098 GB1107

GB1107 (GB-1107, GB 1107) is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with Kd of 37 nM (human Galectin-3).

1978336-61-6
DC21040 GB-83

GB-83 is a selective, reversible PAR2 (Protease-activated receptor 2) antagonist with IC50 of 2 uM.

1252806-86-2
DC12671 Gboxin Featured

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma.

2101315-36-8
DC10474 GBT-440(Voxelotor) Featured

GBT-440(Voxelotor) is a novel small molecule hemoglobin modifier which increases hemoglobin oxygen affinity.

1446321-46-5
DC10896 GCN2-IN-1 Featured

GCN2-IN-1 is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with IC50s of <0.3 μM in the enzyme and cell assay.

1448693-69-3
DC7416 Taselisib(GDC-0032) Featured

GDC-0032 is a potent, next-generation β isoform-sparing PI3K inhibitor targeting PI3Kα/δ/γ with IC50 of 0.29 nM/0.12 nM/0.97nM, >10 fold selective over PI3Kβ.

1282512-48-4
DC3109 Ipatasertib (GDC-0068) Featured

GDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 5 nM, 18 nM and 8 nM, respectively.

1001264-89-6
DC8597 Gdc-0152 Featured

GDC-0152 is a potent inhibitor of IAPs; binds to the XIAP BIR3 domain, the BIR domain of ML-IAP, and the BIR3 domains of cIAP1 and cIAP2 with K(i) values of 28, 14, 17, and 43 nM, respectively.

873652-48-3
DC8216 GDC-0349

GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM; >700-fold selectivity over PI3Kα and other 266 kinases.

1207360-89-1
DC8519 GDC046 Featured

GDC046 is a potent lead analog with good kinase selectivity, physicochemical properties, and pharmacokinetic profile.

1258292-64-6
DC8000 GDC-0623 Featured

GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP).

1168091-68-6
DC23714 GDC-0927 R-form

GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer..

1642297-53-7
DC23717 GDC-0927

GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer..

1642297-01-5
DC7766 Ravoxertinib Featured

GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1.

1453848-26-4
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