| DC34154 |
Citiolone |
Citiolone is a mucolytic agent for the treatment of certain hepatic disorders. |
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| DC34155 |
Sodium D-Pantothenate |
Sodium D-Pantothenate is a vitamin that performs an important role in the oxidation of fats and carbohydrates and certain amino acids. It is also a precursor in the biosynthesis of coenzyme A. |
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| DC34156 |
3,3',5'-Triiodo-L-thyronine |
3,3',5'-Triiodo-L-thyronine, also known as rT3, inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes. The ratio of triiodothryonine (T3) to rT3 has been investigated as in indicator of insulin resistance. |
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| DC34157 |
Ioxitalamic Acid |
Ioxitalamic Acid, also known as Telebrix or Vasobrix, is a medical contrast medium. It enhances the contrast of structures or fluids within the body in medical imaging. |
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| DC34158 |
Isosorbide |
Isosorbide is a precursor of Isosorbide mononitrate or dinitrate, which relax vascular smooth muscle by formation of the free radical nitric oxide (NO). |
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| DC34159 |
Gefarnate |
Gefarnate is an antiulcer agent that stimulates in-vitro secretion of mucin-like glycoprotein in conjunctival tissue. It also ameliorates corneal epithelial damage in animal dry-eye models. |
|
| DC34160 |
Lithocolic acid |
Lithocolic acid is a bile acid formed from chenodeoxycholate by bacterial action. It acts as a detergent to solubilize fats for absorption and is itself absorbed. |
|
| DC34161 |
Pamoic acid |
Pamoic acid is an agonist of the orphan G protein-coupled receptor GPR35. It activates ERK and beta-arrestin2 and causes antinociceptive activity. |
|
| DC34162 |
Bronidox |
Bronidox is an antimicrobial agent. It works by inhibiting enzyme activity in bacteria. |
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| DC34163 |
Diatrizoic Acid Dihydrate |
Diatrizoic Acid Dihydrate is used as a radiocontrast agent for imaging the gastrointestinal tract in patients allergic to barium. |
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| DC34164 |
Hyodeoxycholic acid sodium salt |
Hyodeoxycholic acid sodium salt is a natural secondary bile acid. It improves high-density lipoprotein (HDL) function, reduces farnesoid X receptor antagonist bile acids and the gene expression levels of sterol regulatory element binding protein 1c, acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase-1, and induces strong cytotoxicity, apoptosis and IL-8 synthesis. |
|
| DC34165 |
Ritanserin |
Ritanserin is a selective and potent serotonin-2 antagonist. Ritanserin acts as a selective 5-HT2A (Ki = 0.45 nM) and 5-HT2C receptor (Ki = 0.71 nM) antagonist. |
|
| DC34166 |
Quinine sulfate dihydrate |
Quinine sulfate dihydrate is an antimalarial agent. It works by reducing oxygen intake and carbohydrate metabolism, disrupting DNA replication and transcription via DNA intercalation, and reducing excitability of muscle fibers via alteration of calcium distribution. It is also an inhibitor of P-glycoprotein. |
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| DC34167 |
Eprosartan |
Eprosartan is a competitive and reversible angiotensin II receptor antagonist used for the treatment of high blood pressure. The drug acts on the renin-angiotensin system to decrease total peripheral resistance in two ways. First, it blocks the binding of angiotensin II to AT1 receptors in vascular smooth muscle, causing vascular dilatation. Second, it inhibits sympathetic norepinephrine production, further reducing blood pressure. |
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| DC34168 |
17A-Hydroxyprogesterone |
17A-Hydroxyprogesterone is a metabolite of progesterone. It serves as an intermediate in the biosynthesis of hydrocortisone and gonadal steroid hormones. |
|
| DC34169 |
Propentofylline |
Propentofylline is a phosphodiesterase inhibitor with neuroprotective effect. It was studied for the treatment of Alzheimer's disease and multi-infarct dementia, as well as its action as an adenosine reuptake inhibitor. |
|
| DC34170 |
5-Methyltryptamine hydrochloride |
5-Methyltryptamine hydrochloride acts as a 5-HT receptor agonist. |
|
| DC34171 |
CP-380736 |
CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme. |
|
| DC34172 |
DL-Adrenaline |
DL-Adrenaline is a non-selective adrenoceptor agonist. It induces lipolysis and systemic muscle contraction, and shows systemic vasoconstrictive, bronchodilatory, positive chronotropic and gastrointestinal relaxant effects in vivo. |
|
| DC34173 |
CCT036477 |
CCT036477 is a selective inhibitor of wingless-type MMTV integration site family (WNT)-dependent transcription. It reduces the transcriptional activity of the T-cell factor/lymphoid enhancer factor transcription factor family at the ?-catenin level. |
|
| DC34174 |
DS2 |
DS2 is a selective positive allosteric modulator of d-GABAA receptors. |
|
| DC34175 |
CAPE |
CAPE is an inhibitor of BAF. It works by activating latent HIV-1, inhibiting PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK), hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1). |
|
| DC34176 |
SW203668
Featured
|
SW203668 is a potent, tumor-specific inhibitor of stearoyl CoA desaturase (SCD) with better bioavailability than SW208108. |
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|
| DC34177 |
Glaucine |
Glaucine is an inhibitor of TNF-alpha and IL-6 production induced by Toll-like receptor (TLR) ligands. |
|
| DC34178 |
CBIO |
CBIO is a potent, cell-permeable, D-amino acid oxidase (DAO) reversible inhibitor. In rat models, CBIO prevents formalin-induced tonic pain but not acute nociception. |
|
| DC34179 |
Acyclovir sodium |
Acyclovir sodium is an antimetabolite. It inhibits HSV-specified DNA polymerases and prevents further viral DNA synthesis without affecting the normal cellular processes. |
|
| DC34180 |
Calcein
Featured
|
Calcein is a fluorescent dye that is useful for testing cell viability and for short-term labeling of cells. |
|
| DC34181 |
Y198561 |
Barnidipine Hydrochloride is a long-acting calcium channel blocker. |
|
| DC34182 |
(R)-Citalopram oxalate |
(R)-Citalopram oxalate is a less active enantiomer of Escitalopram Oxalate, a potent and selective inhibitor of serotonin reuptake. |
|
| DC34183 |
L-Dehydroascorbic acid |
L-Dehydroascorbic acid is the oxidized form of L-Ascorbic acid. It selectively induces cell death in KRAS and BRAF mutant cells in vitro. |
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