| DC34091 |
Rifampicin |
Rifampicin is a semisynthetic antibiotic produced from Streptomyces mediterranei with broad antibacterial spectrum. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. |
|
| DC34092 |
AC30341 |
AC30341 is a PqsE inhibitor. It binds to the active center, inhibiting PqsE's thioesterase activity in cell-based and in vitro assays. |
|
| DC34093 |
EGFR inhibitor(YUN27078)
Featured
|
YUN27078, also known as EGFR inhibitor, is an EGFR inhibitor. It directly depolymerizes microtubules and is used as a chemical probe to investigate both the EGFR pathway and microtubule dynamics. YUN27078 hax CAS#879127-07-8, no formal name For the convenience of scientific communication, we named it as YUN27078 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature |
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| DC34094 |
NSC65667 |
SXT1596 is a novel inhibitor of the SS18-SSX/TLE1 interaction. SXT1596 decreases cell viability and reactivates EGR1 expression in synovial sarcoma. |
|
| DC34095 |
PHGDH-inactive |
PHGDH-inactive is an inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503. PHGDH-inactive is intended to serve as a negative control for NCT-502 and NCT-503. |
|
| DC34096 |
MpsBAY2a |
MpsBAY2a is a potent and selective Mps1 inhibitor. It is selective for Mps1 over a panel of 220 kinases. MpsBAY2a differentially inhibits human colon carcinoma cell proliferation. |
|
| DC34098 |
NSC156529 |
NSC156529 downregulates AKT1 signaling, efficiently decreasing the proliferation of human cancer cells in vitro, and substantially inhibiting the growth of prostate tumor xenografts in vivo. |
|
| DC34099 |
Oe-9000 |
Oe-9000 is a novel blocker of voltage-gated Na(+) currents in neurons. It reversibly reduces slowly activating and inactivating tetrodotoxin-resistant (TTX-R) Na(+) currents as well as rapidly activating and inactivating TTX-sensitive (TTX-S) Na(+) currents at low micromolar concentrations. |
|
| DC34100 |
Puromycin Dihydrochloride
Featured
|
Puromycin Dihydrochloride is an antibiotic. It inhibits protein synthesis by binding to RNA. Puromycin Dihydrochloride has antimicrobial, antitrypanosomal, and antineoplastic properties. |
|
| DC34101 |
GLPG-0259 |
GLPG-0259 is a small-molecule inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), a kinase enzyme that plays a role in important inflammatory pathways. |
|
| DC34102 |
PS372424 HCl |
PS372424 HCl is a specific agonist of human CXCR3. It has been shown to induce phosphorylation of ERK and block CXCL11 induced migration of CD45+ cells to air pouches generated on humanized mice. |
|
| DC34103 |
NAAD sodium salt |
NAAD sodium salt initiates intracellular Ca2+ release by a cyclic ADP ribose-independent and IP3 mechanism. It is also used as a substrate to study the specificity and kinetics of nicotinamide adenine dinucleotide synthetase(s) (NADS). |
|
| DC34104 |
Isotetrandrine |
Isotetrandrine is a cell-permeable PLA2 inhibitor. It can block NMO-IgG binding to AQP4 without affecting the expression and function of AQP4. It can also inhibit NMO-IgG binding to astrocyte AQP4 in NMO patient sera and block NMO-IgG-dependent complement-mediated cytotoxicity. |
|
| DC34105 |
PF-3187207 |
Latanoprostene, also known as PF-3187207, is a a nitric oxide (NO)-donating latanoprost with prostaglandin activity. It loweres intraocular pressure (IOP) more effectively than latanoprost in monkeys, dogs and rabbits. |
|
| DC34106 |
N106 |
N106 directly activates the SUMO-activating enzyme, E1 ligase, and triggers intrinsic SUMOylation of SERCA2a. Decreased activity and expression of the cardiac sarcoplasmic reticulum calcium ATPase (SERCA2a), a critical pump regulating calcium cycling in cardiomyocyte, are hallmarks of heart failure. |
|
| DC34107 |
Estradiol Benzoate |
Estradiol Benzoate is a prodrug of estradiol. It acts as a steroid sex hormone while exhibiting mild anabolic and metabolic properties and increasing blood coagulability. |
|
| DC34108 |
Novokinin |
Novokinin is an angiotensin AT2 receptor agonist. Novokinin exhibits vasorelaxing and hypotensive activity via activation of the IP (prostacyclin) receptor, and suppresses food intake via activation of PGE2-EP4 interaction. |
|
| DC34109 |
MSP3 |
MSP3 is a transient receptor potential vanilloid type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. |
|
| DC34110 |
PF-06651481-00 |
PF-06651481-00, also known as Bosutinib Isomer I, is an analog of bosutinib, and a Bcr-Abl kinase inhibitor. |
|
| DC34111 |
ROPA |
ROPA, also known as Resiniferonol 9,13,14-ortho-phenylacetate, is a potent PKCalpha and PKCgamma activator that promotes tumor growth through PKC-activation. |
|
| DC34112 |
PDBu |
Phorbol 12,13-dibutyrate, also known as PDBu, is a phorbol ester which is one of the constituents of croton oil. As an activator of protein kinase C, it is a weak tumor promoter compared to 12-O-tetradecanoylphorbol-13-acetate. |
|
| DC34113 |
Dehydroabietylamine |
Leelamine, also known as NSC-2955, is a selective and potent inducer of hepatic cytochrome P450 2B activity. It is also an inhibitor of intracellular cholesterol transport. |
|
| DC34114 |
Ingenol 3-Hexanoate |
Ingenol 3-Hexanoate novel potent reactivator of latent HIV-1. |
|
| DC34115 |
4alpha-PDD |
4alpha-PDD is a negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA). Though it is inactive for signaling through PKC, 4alpha-PDD has been shown to activate transient receptor potential vanilloid 4 (TRPV4) channels. |
|
| DC34117 |
GSK983 |
GSK983 is a potent broad-spectrum antiviral. It blocks cell proliferation and dengue virus replication by inhibiting the pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase (DHODH). |
|
| DC34118 |
DHBP |
DHBP, also known as Benzoresorcinol, is an activator of WalKR TCS. It works via targeting erWalK and selectively promoting the lysostaphin-induced lysis activity of the Newman wild-type strain. |
|
| DC34119 |
DBT |
DBT is a far-red/near-infrared fluorescence light-up probe for specific in vitro and in vivo imaging of tumour-related proteins. |
|
| DC34120 |
Nifuroxazide |
Nifuroxazide is an antibiotic used for the treatment of colitis and diarrhea in humans and non-humans. |
|
| DC34121 |
Hematin |
Hematin is an iron-containing porphyrin used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
|
| DC34122 |
Turimycin |
Turimycin is a macrolide antibiotic that is effective against a wide spectrum of pathogens. |
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