DC34215 |
Bacitracin |
Bacitracin is an antibiotic. It has been shown to disrupt gram positive bacteria by interfering with cell wall and peptidoglycan synthesis. |
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DC34216 |
Acetyl-L-carnitine |
Acetyl-L-carnitine is a stimulator of α-secretase activity and metabolism of amyloid precursor protein (APP). It has been shown to induce NF-κB-mediated upregulation of mGluR2 receptors, thereby exhibiting antidepressant, neuroprotective, analgesic, and antinociceptive activities. |
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DC34217 |
Proscillaridin |
Proscillaridin, also known as Proscillaridin A, is a cardiotonic glycoside. It potently disrupts topoisomerase I and II activity. |
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DC34218 |
Cytochalasin D |
Cytochalasin D is a fungal metabolite. It blocks formation of contractile microfilament structures, resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. It also inhibits actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release. |
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DC34219 |
MMV665852 |
MMV665852 is an antischistosomal agent. It has been shown to inhibit worm viability in vitro and reduce worm burden in S. mansoni-infected mice. |
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DC34220 |
Moxalactam Disodium |
Moxalactam Disodium is a broad- spectrum beta-lactam antibiotic. |
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DC34221 |
PF2562 |
PF2562 is a non-catechol dopamine 1 receptor agonist. Dopamine D1 receptors are implicated in numerous neuropharmacological and neurobiological functions. For example, D1 receptors are involved in different types of memory function and synaptic plasticity. |
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DC34222 |
AG-183 |
AG-183 is an inhibitor of epidermal growth factor (EGF) receptor kinase. |
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DC34223 |
Seretide |
Seretide is a combination of fluticasone and salmeterol that is used as an inhaler formulation to manage the symptoms of asthma and chronic obstructive pulmonary disease (COPD). |
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DC34225 |
Aminoluciferin |
Aminoluciferin is a luciferin derivative as functional bioluminogenic substrate. |
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DC34226 |
Auxin |
Auxin is a plant hormone growth regulator. |
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DC34227 |
Indican |
Indican is a natural protective agent to the liver. |
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DC34229 |
Monoelaidin |
Monoelaidin is an enhancer of the solubility and oral bioavailability for poorly water-soluble drugs. |
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DC34230 |
5-Methylcytosine |
5-Methylcytosine is a methylated cytosine. It acts as a ligand of the hDNMT1. |
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DC34231 |
S32826 |
S32826 is an inhibitor of autotaxin. |
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DC34232 |
TPCK |
TPCK is a non-specific irreversible inhibitor of serine/cysteine proteases. It acts by inhibiting ScRce1 in the presence of a Ras reporter, but not in the presence of the a-factor peptide. |
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DC34233 |
CP-96345 |
CP-96345 is a potent and selective non-peptide NK1 receptor antagonist. |
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DC34235 |
Digitoxigenin |
Digitoxigenin is a precursor of cardiac glycosides. It acts by targeting the metastatic uveal melanoma gene signature. |
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DC34236 |
p-BrBzGSH(Cp)2 |
p-BrBzGSH(Cp)2 is an inhibitor of glyoxylase 1 (GLO1). It acts by increasing DNA-AGEs, stimulating RAGE expression, and inhibiting brain tumor growth in orthotopic mouse models. |
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DC34237 |
Methylenebis |
Methylenebis is an autophagy-regulator. It acts by sensitizing tumor cells to belotecan, a derivative of camptothecin, as a topoisomerase I inhibitor. |
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DC34238 |
Ectoine
Featured
|
Ectoine is an inhibitor of protein misfolding. It acts by significantly down-regulating Syp, Mapk3 and Tnfα and up-regulating Vegf in rat's hippocampus, prohibiting insulin amyloid formation in vitro. |
|
DC34239 |
Trimosulfa |
Trimosulfa is a fixed antibiotic combination. It is widely used for mild-to-moderate bacterial infections and as prophylaxis against opportunistic infections. |
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DC34240 |
JR-AB2-011
Featured
|
JR-AB2-011 is a potent and selective inhibitor of mTORC2 kinase activity. It markedly reduces mTORC2 signaling and IC50 while enhancing apoptotic levels in GBM cells. |
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DC34241 |
TASIN-1 Hydrochloride |
TASIN-1 Hydrochloride is a truncated APC selective inhibitor. It acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells. |
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DC34242 |
MG115
Featured
|
MG-115(MG 115) is an inhibitor of NFκB in the cytoplasm by acting on IKK or the proteasome. |
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DC34244 |
KLH45
Featured
|
KLH45 is a selective inhibitor of DDHD2 (DDHD domain containing 2). |
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DC34245 |
BSBM7 |
BSBM7 is an inhibitor of Aβ aggregation and neuronal toxicity. It acts by reversing the aggregation and toxicity of amyloid-β (Aβ) peptides. |
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DC34246 |
Amodiaquin dihydrochloride |
Amodiaquin dihydrochloride is an inhibitor of the Ebola virus. It acts by targeting the viral protein 35 (VP35). |
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DC34247 |
TLCK hydrochloride |
TLCK hydrochloride is a blocker of the LPS- or cytokine-induced activation of nuclear factor κB (NF-κB). |
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DC34248 |
SKF-10047 |
SKF-10047 is a sigma-1 receptor agonist. |
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