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Ectoine

  Cat. No.:  DC34238   Featured
Chemical Structure
96702-03-3
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Field of application
Ectoine is an inhibitor of protein misfolding. It acts by significantly down-regulating Syp, Mapk3 and Tnfα and up-regulating Vegf in rat's hippocampus, prohibiting insulin amyloid formation in vitro.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 96702-03-3
Chemical Name: (6S)-2-Methyl-1,4,5,6-tetrahydropyrimidine-6-carboxylic acid
Synonyms: Ectoine;
SMILES: O=C([C@@H]1CCN=C(C)N1)O
Formula: C6H10N2O2
M.Wt: 142.15
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare[1]. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis[2].
Target: Bacterial[1]
References: [1]. Werkhäuser N, et al. Treatment of allergic rhinitis with ectoine containing nasal spray and eye drops in comparison with azelastine containing nasal spray and eye drops or with cromoglycic Acid containing nasal spray. J Allergy (Cairo). 2014;2014:176597. [2]. Graf R, et al. The multifunctional role of ectoine as a natural cell protectant. Clin Dermatol. 2008 Jul-Aug;26(4):326-33.
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