DC36030 |
Alcophosphamide |
Alcophosphamide is a urinary metabolite of cyclophosphamide which may be used in proteomics research. |
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DC36031 |
Glyceryl monooleate |
Glyceryl monooleate is a biochemical which may be used as a nanocarrier for drug delivery. |
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DC36032 |
Aldrin-transdiol |
Aldrin-transdiol is a metabolite of dieldrin. Aldrin-transdiol may be used in insecticides. |
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DC36033 |
Tiropramide hydrochloride |
Tiropramide hydrochloride is a smooth muscle antispasmodic agent which has been shown to to have some efficacy in normalizing intestinal transit time and in inducing symptomatic relief for Irritable Bowel Syndrome (IBS) patients. |
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DC36034 |
Aloesin |
Aloesin is a competitive tyrosinase inhibitor. As an Aloe chromone, Aloesin has previously been formulated with an aloe polysaccharide to give a composition called Loesyn, where it showed significant impact in reducing glycosylated hemoglobin, fasting blood glucose, fructosamine and plasma insulin level in humans. This molecule has also been shown to modulate melanogenesis and have some anti-inflammatory effects in rats. |
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DC36035 |
Aloperine |
Aloperine is an alkaloid with diverse biological activities including antiviral, anticancer, antioxidant, and anti-inflammatory actions. It inhibits HIV-1 replication and envelope-mediated cell-cell fusion in vitro. Aloperine also inhibits the growth of HL-60, U937, and K562 leukemia cell lines. |
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DC36036 |
Memantine |
Memantine is an amantadine derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent and has may be used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors. |
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DC36037 |
AM 6201 |
AM 6201, also known as Reductiomycin, is an alkaloid originally derived from Streptomyces xanthochromogenus that has been shown to exhibit antitumor activity against Ehrlich ascites carcinomas in mice. |
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DC36038 |
AM-1172 |
AM-1172 is an endocannabinoid analog specifically designed to be a potent and selective inhibitor of AEA uptake that is resistant to FAAH hydrolysis. |
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DC36039 |
AMD-8664 |
AMD-8664 is an HIV entry inhibitor which was being developed by AnorMED in the US in conjunction with the Rega Institute of Leuven. AMD-8664 works by antagonizing the HIV-1 entry co-receptor CXCR4. AMD-8664 may be useful for the clinical treatment of HIV-1-infected patients, especially at the late stage of treatment for AIDS patients developing multi-drug-resistant strains. |
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DC36040 |
Amlodipine besilate impurity G |
Amlodipine besilate impurity G is a biochemcical. |
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DC36041 |
Amlodipine besilate impurity D |
Amlodipine besilate impurity D is a biochemical. |
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DC36042 |
Amlodipine besilate impurity E |
Amlodipine besilate impurity E is a biochemical. |
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DC36043 |
Amlodipine besilate impurity F |
Amlodipine besilate impurity F, also known as Amlodipine Dimethyl Ester, is a biochemical. |
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DC36044 |
Amlodipine besilate impurity B |
Amlodipine besilate impurity B is a biochemical. |
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DC36045 |
Amthamine |
Amthamine is a selective histamine H2 receptor agonist which does not stimulate activity of H1 and H3 receptors. Similar to histamine, Amthamine inhibits receptor -mediated eosinophil peroxidase. Amthamine has been shown to suppress the release of serotonin and has been used to study the involvement of H1 and H2 receptors on ion secretion. |
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DC36046 |
Ambazone |
Ambazone is an antiseptic agent with potential antibacterial and antileukemic activity. Although the exact mechanism of action remains unclear, ambazone appears to interfere with the membrane-bound nucleotide system by increasing the intracellular concentration of cAMP in leukemia cells and macrophages, which potentially contributes to this agent's antineoplastic activity. |
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DC36047 |
beta-Amyrin |
beta-Amyrin is a molecule which has been shown to exhibit long-lasting antinociceptive and anti-inflammatory properties. beta-Amyrin activates cannabinoid receptors CB1 and CB2 and inhibits the production of cytokines and expression of NF-κB, CREB and cyclooxygenase 2. |
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DC36048 |
Chloramben-sodium |
Chloramben-sodium is an herbicide. |
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DC36049 |
Amiloride |
Amiloride is a medication typically used with other medications to treat high blood pressure or swelling due to heart failure or cirrhosis of the liver. In the USA, this drug is available via prescription only. |
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DC36050 |
Amisometradine |
Amisometradine is a diuretic which may be used in the treatment of congestive heart failure. |
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DC36051 |
Anatabine |
Anatabine is one of the minor alkaloids found in plants in the Solanaceae family, which includes the tobacco plant and tomato. Anatabine may be useful for treating nicotine addiction and inflammation, Alzheimer's Disease, thyroiditis, and multiple sclerosis. |
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DC36052 |
(-)-Alkannin |
Alkannin is an antioxidant. It is also known to have wound healing, antitumor, and antithrombotic properties. |
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DC36053 |
Amcinafal |
Amcinafal is a topical steroidal anti-inflammatory. |
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DC36054 |
N-Antipyrinylnicotinamide |
Nifenazone is a drug used as an analgesic for a number of rheumatic conditions. |
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DC36055 |
Antazoline phosphate |
Antazoline phosphate is an antihistamine with anticholinergic properties used to relieve nasal congestion and the symptoms of allergic conjunctivitis. Antazoline is an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, and gastrointestinal and bronchial smooth muscles. |
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DC36056 |
Aminoform |
Methenamine is an anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. |
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DC36057 |
Pyrantel pamoate |
Pyrantel pamoate is a broad spectrum antinematodal anthelmintic. |
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DC36058 |
Alkiron |
Methylthiouracil is thiourea antithyroid agent that inhibits the synthesis of thyroid hormone. It is used in the treatment of hyperthyroidism. |
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DC36059 |
Antibiotic 1037
Featured
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Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage, with an IC50 of 80 nM. Toyocamycin (Vengicide) induces apoptosis. Toyocamycin (Vengicide) shows no effect on IRE1α auto-phosphorylation[1]. |
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