| DC38061 |
Isoloratadine |
Isoloratadine is a Loratadine impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases. |
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| DC38062 |
Omeprazole sodium |
Omeprazole sodium is the salt analogue of Omeprazole, which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative. |
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| DC38063 |
Trityllosartan |
Trityllosartan is an intermediate in the preparation of Losartan impurities. |
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| DC38064 |
Lotaustralin |
Lotaustralin is a cyanogenic glycoside. |
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| DC38065 |
DN 90 |
Cyanox CY 1790 is an antioxidant. |
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| DC38066 |
Boldine |
Boldine is an alkaloid of the aporphine class that can be found in the boldo tree and in Lindera aggregata. Boldine has antioxidant activity that effectively protects against free radical induced lipid peroxidation or enzyme inactivation. In addition, it has alpha-adrenergic antagonist activities in vascular tissue, and it has also been reported to have hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects. |
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| DC38067 |
Capsicine |
Capsaicin is an active component of chili peppers, which are plants belonging to the genus Capsicum. It is an irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Pure capsaicin is a volatile, hydrophobic, colorless, odorless, crystalline to waxy compound. |
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| DC38068 |
PYR-9588 |
PYR-9588, CAS#2199-58-8, is a useful intermediate for chemical synthesis of a number of biologically important molecules, including porphyrins, bile pigments, photosensitizers, anticancer drugs. |
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| DC38069 |
PYR-4897 |
PYR-4897, CAS#60024-89-7, is a useful intermediate for chemical synthesis of a number of biologically important molecules, including porphyrins, bile pigments, photosensitizers, anticancer drugs. |
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| DC38070 |
TPY-5628 |
TPY-5628, CAS#149365-62-8, is a useful intermediate for chemical synthesis of a number of biologically important molecules, including porphyrins, bile pigments, photosensitizers, anticancer drugs. |
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| DC38071 |
DBB-0920 |
DBB-0920, CAS#4440-92-0, is a dibenzene-butanedione derivative nad a useful intermediate for chemical synthesis of terameprocol and a number of biologically important molecules. |
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| DC38072 |
DBF-6339 |
DBF-6339, CAS#4676-33-9, is a dibenzene-furan derivative and a useful intermediate for chemical synthesis of a number of biologically important molecules, including anticancer drugs. |
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| DC38073 |
Octaethyl-porphyrin |
Octaethylporphyrin, CAS#2683-82-1, is a stable and useful porphyrin compound for research use. |
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| DC38074 |
benzoporphyrin derivative Ring A -1 |
VWN38241, also known as BPD-A-1,4-diene , and benzoporphyrin derivative Ring A -1,4-diene, is an important precursor for making PDT drug verteporfin. Verteporfin (trade name Visudyne), a benzoporphyrin derivative, is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. VWN38241 has CAS#94238-24-1 and inchi key VTMVQLSZTQAYOV-WKGWVRGVSA-N. For the convenience of scientific communication, tt is named as VWN38241 according to Hodoodo Chemical Nomenclature. |
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| DC38075 |
Benzoporphyrin Ring B 1,4-diene |
SSN38434, also known as BPD-B-1,4-diene and Benzoporphyrin Ring B 1,4-diene, is a product from the synthesis of verteporfin. BPD-B-1,4-diene may be useful for making porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic (PDT) drugs. SSN38434 has CAS#94238-43-4. For the convenience of scientific communication, It is named as SSN38434 according to Hodoodo Chemical Nomenclature. Synthesis of SSN38434 was reported in J. org. Chem 1986, 51(7):1094-100. Note: SSN38434 was previously name as OZN38434. |
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| DC38076 |
BPD-Ring B |
LZN86178, also known as BPD-Ring B and benzoporphyrin Ring B derivative, is a product from the synthesis of verteporfinin. BPD-Ring B may be useful for making porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic (PDT) drugs. LZN86178 has CAS#143986-17-8. For the convenience of scientific communication, tt is named as LZN86178 according to Hodoodo Chemical Nomenclature. |
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| DC38077 |
DBB-7373 |
DBB-7373, CAS#36287-37-3, is a Dibenzene-butandione derivative. DBB-7373 is a useful intermediate for synthesis of teremeprocol and other bioactive chemicals and drugs. |
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| DC38078 |
6-Chloro-1-tetralone |
6-Chloro-1-tetralone is an important intermediate for the synthesis of pharmaceutical compounds. |
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| DC38080 |
SMCC |
SMCC, also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a heterobifunctional protein crosslinker. SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 angstroms). SMCC conjugation occurs via a maleimide group that is sulfhydryl (thiol; -SH) reactive and a NHS ester group that is amine reactive and forms stable, covalent protein crosslinks. |
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| DC38081 |
Paclitaxel-Succinic acid |
Paclitaxel-Succinic acid, also known as Paclitaxel Succinate or Paclitaxel-hemisuccinic acid, is a paclitaxel derivative with a succinic acid linker. The carboxy group of Paclitaxel-Succinic acid, after activiating, can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research. |
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| DC38082 |
Paclitaxel-MVCP |
Paclitaxel-MVCP, also known as MC-Val-Cit-PAB-Paclitaxel, is a paclitaxel derivative with a MC-Val-Cit-PAB linker. Mc-Val-Cit-PAB is a cathepsin cleavable ADC peptide linker. Paclitaxel-MVCP can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-MVCP is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research. |
|
| DC38083 |
WZ4002-hydroxy |
WZ4002-hydroxy is a WZ4002 (MedKoo Cat#: 203170) derivative or WZ4002 analog. In which the methoxy group is replaced by hydroxy group. WZ4002 is EGFR inhibitor against EGFR T790M (mutation of the gatekeeper T790 residue) which is detected in 50% of clinically resistant patients to gefitinib or erlotinib. WZ4002 has a basic chemical framework (covalent pyrimidine) which is different from that of other EGFR inhibitors. |
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| DC38084 |
WZ8040-hydroxy |
WZ8040-hydroxy is a WZ8040 (MedKoo Cat#406574) derivative or analog molecule. Compared to WZ8040, WZ8040-hydroxy has an extra hydroxy group in the benzene ring. WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor with potential anticancer activity. WZ8040 is about 30-fold more potent against EGFR T790M, and up to 100-fold less potent against wild-type EGFR, than other quinazoline-based EGFR inhibitors such as CL-387785 and HKI-272. WZ-8040 may be clinically more effective and better tolerated than quinazoline-based inhibitors. |
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| DC38085 |
L-allo-Isoleucine |
L-allo-Isoleucine may be used in studies on maple syrup urine disease (MSUD). In patients with classical MSUD (n = 7), alloisoleucine was beyond the cutoff value in 2451 of 2453 unselected samples. In patients with variant MSUD (n = 9), alloisoleucine was >5 micromol/L in all samples taken for establishment of diagnosis and in 94% of the samples taken for treatment control (n = 624). With the other branched-chain amino acids, the frequency of diagnostically significant increases was <45%. The plasma L-alloisoleucine above the cutoff value of 5 micromol/L is the most specific and most sensitive diagnostic marker for all forms of MSUD. |
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| DC38086 |
PRP194 |
PRP-194, CAS#596085-87-9, has a chemical name 5-chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine, is a useful precursor for chemical synthesis of bioactive molecules and dyes. There is no formal name for this chemical. For the convenience of communication, we temporally called it as PRP-194, in which PRP is originated from PyRrolo[2,3-b]Pyridine, and 194 is originated from its molecule weight 194. |
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| DC38087 |
Decyl-TPP |
Decyl-TPP, also known as (1-Decyl)triphenylphosphonium bromide, may be used as intermediate for chemical synthesis, Decyl-TPP can be also used as an inactive control or as a reference to mitoquinone (MitoQ). |
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| DC38088 |
MDK08445 |
MDK08445 is an important intermediate or precursor for the synthesis of Cefiderocol. MDK08445 has CAS#1225208-44-5. We assigned a code name as MDK08445 (last 5 digital of its CAS# was used). Cefiderocol, also known as S-649266, is a potent siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. S-649266 shows potent in vitro activity against the non-fermenting Gram-negative bacteria Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia, including MDR strains such as carbapenem-resistant A. baumannii and metallo-β-lactamase-producing P. aeruginosa. |
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| DC38089 |
MDK71803 |
MDK71803 is an important intermediate or precursor for the synthesis of Cefiderocol. MDK71803 has CAS#137171-80-3. We assigned a code name as MDK71803 (last 5 digital of its CAS# was used). Cefiderocol, also known as S-649266, is a potent siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. S-649266 shows potent in vitro activity against the non-fermenting Gram-negative bacteria Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia, including MDR strains such as carbapenem-resistant A. baumannii and metallo-β-lactamase-producing P. aeruginosa. |
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| DC38090 |
Biotin-PEG6-Maleimide |
Biotin-PEG6-Maleimide is a PEG derivative containing a biotin group and a maleimide group for labeling and crosslinking cysteines and other sulfhydryls. The maleimide group reacts specifically with sulfhydryl groups (at pH 6.5-7.5) to form a stable, irreversible thioether linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. |
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| DC38091 |
Fmoc-Val-Ala-PAB |
Fmoc-Val-Ala-PAB, also known as Fmoc-Val-Ala-PAB-OH, is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. |
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