| DC38092 |
Mc-Val-Ala-PAB |
Mc-Val-Ala-PAB is a useful linker to make antibody-drug-conjugate (ADC) for targeting drug delivery. |
|
| DC38093 |
8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine |
The chemcial name of CAS# 873436-91-0 is 8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine |
|
| DC38094 |
t-Boc-N-amido-PEG9-amine |
t-Boc-N-amido-PEG9-amine is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine. PEG Linkers are useful in the development of antibody drug conjugates. |
|
| DC38095 |
(R)-Ofloxacin |
(R)-Ofloxacin is a R-isomer of Ofloxacin, which is an antibiotic useful for the treatment of a number of bacterial infections. |
|
| DC38096 |
HKI272 maleate |
Neratinib, also known as HKI-272 or PB272, is an orally available, irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. |
|
| DC38098 |
Thiodipropionic acid |
Thiodipropionic acid is an organic disulfide used as a ligand for the synthesis of cadminum and zinc coordination polymers that have luminescent properties. |
|
| DC38099 |
Exifone |
Exifone is a bioactive chemical. |
|
| DC38100 |
p-Cresol |
para-Cresol, also 4-methylphenol, is an organic compound with the formula CH?C?H?. It is a colourless solid that is widely used intermediate in the production of other chemicals. |
|
| DC38102 |
dimethoxydocetaxeld-6 |
Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance (MDR), P-glycoprotein (P-gp) efflux pump and may be useful for treating multidrug-resistant tumors. In addition, cabazitaxel penetrates the blood-brain barrier (BBB). |
|
| DC38104 |
Phosphatidylcholines (PC) |
Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of biological membranes and can be easily obtained from a variety of readily available sources, such as egg yolk or soybeans, from which they are mechanically or chemically extracted using hexane. They are also a member of the lecithin group of yellow-brownish fatty substances occurring in animal and plant tissues. Dipalmitoyl phosphatidylcholine (aka: lecithin) is a major component of pulmonary surfactant and is often used in the L/S ratio to calculate fetal lung maturity. While phosphatidylcholines are found in all plant and animal cells, they are absent in the membranes of most bacteria, including Escherichia coli. Purified phosphatidylcholine is produced commercially. |
|
| DC40082 |
Yubeinine |
Yubeinine is an alkaloid, isolated from the bulbs of Fritillaria yuminensis. |
|
| DC40120 |
(R)-Gyramide A hydrochloride |
(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 μM. (R)-Gyramide A hydrochloride demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs of 10-80 μM). (R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV. |
|
| DC40189 |
N1,N12-Diacetylspermine dihydrochloride |
N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of spermine. Upregulation of N1,N12-Diacetylspermine dihydrochloride has been linked to the incidence of cancer, making it to be a potential biomarker for cancer detection. |
|
| DC40202 |
Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside |
Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside, obtained from D-ribose, is an intermediate for the synthesis of riboside-containing arsenic compound. |
|
| DC40203 |
Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside |
Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside is an enantiomer of Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside. Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside is a derivative of L-ribose. |
|
| DC40204 |
Pronase E (Activity≥4000 U/mg) |
Pronase E (Activity≥4000 U/mg) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids. |
|
| DC40222 |
(S)-ZINC-3573
Featured
|
(S)-ZINC-3573 is a negative control for (R)-ZINC 3573. (S)-ZINC-3573 displays no activity at MRGPRX2 at concentrations below 100 μM. |
|
| DC40223 |
2-Undecanol |
2-Undecanol (Undecan-2-ol) is a male specific volatile identified from the sap beetle Lobiopa insularis. 2-undecanol is a flower emitted volatile, used by various species of Hymenoptera as a pheromone component. |
|
| DC40255 |
3-Keto petromyzonol |
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey. |
|
| DC40283 |
Homobaldrinal |
Homobaldrinal is a decomposition product of Valepotriate. Homobaldrinal exhibits genotoxic activity in the Salmonella/microsome test.
|
|
| DC40290 |
Yibeissine |
Yibeissine is a steroidal alkaloid isolated from the bulb of Fritillaria pallioiflora Schren. |
|
| DC40356 |
Lupeol acetate |
Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B. |
|
| DC40454 |
Microcolin B |
Microcolin B is an extremely potent unusual acylpeptide, proline-containing potent immunosuppressant. Microcolin B is isolated from blue-green alga Lyngbya majuscule. |
|
| DC40494 |
β-Aspartylaspartic acid |
β-Aspartylaspartic acid is a natural compound found in Asparagus (Asparagus officinalis) Shoots. |
|
| DC40502 |
Dihydrojasmonic acid |
Dihydrojasmonic acid is a plant growth regulator. |
|
| DC40713 |
N-(3-Oxotetradecanoyl)-DL-homoserine lactone |
N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule. |
|
| DC41291 |
2'-Aminoacetophenone |
2'-Aminoacetophenone is an aromatic compound containing a ketone substituted by one alkyl group, and a phenyl group. 2'-Aminoacetophenone can be used as a breath biomarker for the detection of Ps. Aeruginosa infections in the cystic fibrosis lung. |
|
| DC41301 |
(Z)-Akuammidine |
(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans. |
|
| DC41302 |
Manool |
Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G(2)/M phase of the cell cycle. |
|
| DC41304 |
Scopoletin acetate |
Scopoletin acetate is a coumarin isolated from Artemisia granatensis. |
|
