| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73960 | CW4142 | CW4142 (CW 4142) is a small molecule SC4MOL inhibitor that enhances oligodendrocyte formation. |
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| DC73961 | CW5107 | CW5107 (CW 5107) is a small molecule HSD17B7 inhibitor that enhances oligodendrocyte formation. |
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| DC73962 | Cytochalasin B | Cytochalasin B is a cell-permeable mycotoxin that inhibits network formation by actin filaments, inhibits cell movement and induces nuclear extrusion. |
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| DC73963 | DB2313 Featured | DB2313 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 29 nM. |
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| DC73964 | DC-SX029 | DC-SX029 is a new small-molecule sorting nexin 10 (SNX10) inhibitor (KD=0.935 uM), blocks the SNX10-PIKfyve interaction, decreases TBK1/c-Rel signaling activation. |
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| DC73965 | DDIT | DDIT is a potent, non-toxic inhibitor of hyaluronan synthesis via targeting hyaluronan synthase (HAS), significantly suppresses the aggressiveness of triple-negative breast cancer cells grown in tissue culture. |
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| DC73966 | DDX3X helicase 64 | DDX3X helicase 64 is a potent, selective inhibitor of DDX3X helicase activity with IC50 of 0.14 μM, shows promising anti-HCV activity, with an EC50 of 0.2 μM and cytotoxicity of 86 μM. |
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| DC73967 | DDX3X helicase 79 | DDX3X helicase 79 is a potent, selective inhibitor of DDX3X helicase activity with IC50 of 5 nM, shows antiviral activity against DENV-2 and WNV with EC50 of 1.6 and 2.3 uM, respectively. |
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| DC73968 | DDX3X helicase 86 | DDX3X helicase 87 is a potent, selective and aller inhibitor of DDX3X helicase activity with IC50 of 7 nM, shows antiviral activity against DENV-2 and WNV with EC50 of 6.3 and 0.88 uM, respectively. |
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| DC73969 | DFO-5 | DFO-5 (Oseltamivir Epoxy Impurity) is an oseltamivir impurity. |
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| DC73970 | DFTD | DFTD is a time-dependent, reversible and covalent inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K) targeting of Cys-146, DFTD binds to the ATP binding site of eEF-2K. |
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| DC73971 | DHAB | DHAB is a potent, specific small molecule inhibitor of kidney ADPR-cyclase with IC50 of 2.5 nM, does not inhibit CD38, spleen, heart or brain ADPR-cyclase activity in vitro. |
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| DC73972 | DHC-156 | DHC-156 is a covalent small molecule inhibitor of oncogenic transcription factor brachyury, selectively binds to brachyury, DHC-156 is potent brachyury downmodulator with DC50 of 4.1 uM. |
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| DC73973 | Dibutepinephrine | Dibutepinephrine is a sympathomimetic compound. |
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| DC73974 | Dichloroallyl lawsone | Dichloroallyl lawsone (Dichlorolapachol, DCL, NSC-126771) is a synthetic analogue of the antimalarial lapachol, inhibits mitochondrial dihydroorotate dehydrogenase (DHODH) with antineoplastic activity. |
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| DC73975 | Dihydrorhodamine 123 | Dihydrorhodamine 123 (DHR 123) is a cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite.. |
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| DC73976 | DiI | Dil (DiIC18(3)) is a fluorescent neuronal tracer that labels cell bodies, axons, dendrites, and dendritic spines. |
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| DC73977 | DKC1125 | DKC1125 is a small molecule KSRP-binding compound that specifically inhibits the oncogenic KITENIN complex, suppresses distant metastasis of colorectal cancer (CRC). |
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| DC73978 | DS07551382 | DS07551382 (DS 07551382) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1), suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
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| DC73979 | DS21150768 | DS21150768 is a potent selective and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with IC50 of 3.27 nM in cell-free HPK1 assays, binds to HPK1 with an affinity constant (KD) of 6.08 nM. |
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| DC73980 | DS55980254 Featured | DS55980254 (DS 55980254) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1) inhibitor, suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
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| DC73981 | DS68591889 | DS68591889 (PTDSS1i) is a potent, selective phosphatidylserine synthase 1 (PTDSS1) inhibitor, highly sellective over PTDSS2, induces phospholipid imbalance in a wide range of cancer cells. |
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| DC73982 | DSHN-OMe | DSHN-OMe (DSHN methyl ester) is a small molecule modulator of NR0B2, effectively reduces induction of LXR target gene ABCA1 by GW3965 (1 uM) in BMDMs with IC50 of 3.8 uM, reduces regulatory T cell expansion and impede breast cancer progression. |
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| DC73983 | DSK638 | DSK638 (DSK-638) is a potent small moelcule RECK inducer, binds histone deacetylases (HDACs) with IC50 of 5-10 uM for HDAC1/3. |
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| DC73984 | DSRM-3716 | DSRM-3716 (DSRM3716, 5-iodoisoquinoline) is a potent and selective inhibitor of NADase SARM1 with IC50 of 75 nM, displays selectivity against various NAD metabolizing and pathway enzymes (e.g., NAMPT and NMNAT). |
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| DC73985 | Ederimotide | Ederimotide (WT1-A1) is a synthetic peptide derived from nonamer sequences of the Wilms tumor protein 1 (WT1), increases human T-cell responses and shows potential as cancer vaccine. |
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| DC73986 | EML417 | EML417 is a small molecule that selectively interactes with the Tudor domain of PHF20. |
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| DC73987 | Endosidin17 | Endosidin17 (ES17) is a small molecule targets retromer component VPS35, binds to VPS35 Impairs interaction with RABG3f, causes dose-dependent stabilization of VPS35 with EC50 of 0.9 uM. |
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| DC73988 | EP055 | EP055 (EP-055) is a small molecule that targets EPPIN on the surface of sperm and inhibits motility (IC50=199.5 uM, CASA assay using human sperm), binds to the C-terminal domain of EPPIN. |
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| DC73989 | EPIC-0412 | EPIC-0412 is a small-molecule inhibitor that enhances the chemotherapeutic effect of temozolomide (TMZ) by acting on the p21-E2F1 DNA damage repair axis and ATF3-p-p65-MGMT axis. |
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