Cat. No. | Product name | CAS No. |
DC22004 |
ATV399
ATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase9 levels with IC50 of 3.3 uM, inhibits dimerization of iNOS. |
393834-37-2 |
DC20114 |
ATWLPPR Peptide TFA
ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1, used in the research of angiogenesis. ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes. |
|
DC23401 |
AU1
AU1 (GSK 1379725A) is the first selective small molecule inhibitor of BPTF bromodomain (bromodomain PHD finger transcription factor) with Kd of 2.8 uM in a cell-based reporter assay, shows no binding activity for Brd4. |
1802251-00-8 |
DC21865 |
Aumitin
Featured
Aumitin is a novel potent autophagy inhibitor with IC50 of 124 and 244 nM against starvation- and rapamycin- induced autophagy respectively, targets mitochondrial complex I. |
946293-78-3 |
DC12428 |
AUNP-12
Featured
AUNP-12 (Aurigene-012) is a PD-1 inhibitor peptide, blocks the PD-1/PD-L1, PD-1/PD-L2 and PD-L1/CD80 pathways. |
1353563-85-5 |
DC26036 |
Aurantiamide acetate
Aurantiamide acetate suppresses the growth of malignant gliomas in vitro and in vivo by inhibiting autophagic flux. |
56121-42-7 |
DC20312 |
Aurintricarboxylic acid
Aurintricarboxylic acid (ATA) is a potent small molecule inhibitor of RISC loading with IC50 of 0.47 uM, inhibits RISC activity against transiently expressed reporters and endogenous genes. |
4431-00-9 |
DC10138 |
Auristatin E
Featured
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. |
160800-57-7 |
DC20037 |
Aurora inhibitor 1
Aurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase, respectively. |
2227019-45-4 |
DC26118 |
AKI-7169(Aurora Kinase Inhibitor III)
Featured
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM). |
879127-16-9 |
DC21866 |
Autotaxin inhibitor 12
Autotaxin inhibitor 12 is a highly potent, selective, orally-bioavailable inhibitor of autotaxin with IC50 of 3.1 nM in choline release assays. |
1613513-14-6 |
DC20701 |
Autotaxin inhibitor compound 1
Autotaxin inhibitor compound 1 (Autotaxin-IN-1) is a potent, selective, orally bioavailable inhibitor of autotaxin with IC50 of 2.2 nM in ex vivo human whole blood assay, does not inhibit related proteins ENPP1 and ENPP7. |
1619971-30-0 |
DC22219 |
Auxin agonist RN3
Auxin agonist RN3 (RubNeddin 3) is a potent, selective auxin agonist that induces specific AUX/IAA protein degradation to modulate plant development. |
425609-03-6 |
DC22220 |
Auxin agonist RN4
Auxin agonist RN4 (RubNeddin 4) is a potent, selective auxin agonist that induces specific AUX/IAA protein degradation to modulate plant development. |
433950-87-9 |
DC22012 |
Avanbulin
Avanbulin (BAL27862, BAL-27862) is a novel microtubule-destabilizing agent that potently inhibits tubulin assembly at 37°C with IC50 of 1.4 uM in tubulin-binding assays. |
798577-91-0 |
DC1094 |
Avasimibe
Featured
Avasimibe inhibits ACAT and CYP2C9 with IC50 of 3.3 μM and 2.9 μM, respectively. |
166518-60-1 |
DC20703 |
AVE-0118
AVE-0118 is a potent I(to)/I(Kur) blocker, Kv1.5 channel inhibitor with IC50 of 5.6 uM, also blocks Kv1.3, Kv2.1, Kv3.1, and Kv4.3 channels with similar potency. |
498577-53-0 |
DC10732 |
Anavex-2-73 free base (Blarcamesine)
Featured
AVex-73 is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease |
195615-83-9 |
DC12715 |
AVG-233
AVG-233 (AVG233) is a potent, allosteric inhibitor of respiratory syncytial virus (RSV) RNA-dependent RNA polymerase (RdRp) complex, demonstrates nanomolar activity against both laboratory-adapted RSV strains and clinical RSV isolates (EC50=34-79 nM). |
2151937-80-1 |
DC8351 |
Avibactam sodium
Featured
Avibactam sodium(NXL-104) is a non-β-lactam β-lactamase inhibitor antibiotic. |
1192491-61-4 |
DC24068 |
AVL-292 besylate
Featured
AVL-292 besylate (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of <1 nM. |
1360053-81-1 |
DC8565 |
AVN944
Featured
AVN-944(VX-944) is a selective, noncompetitive inhibitor of the enzyme directed against human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. |
297730-17-7 |