| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC23203 | E4CPG Featured | A non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist.. |
|
| DC24159 | (R)-Flurbiprofen | A non-steroidal anti-inflammatory drug (NSAID). |
|
| DC22769 | Droloxifene | A nonsteroidal selective estrogen receptor modulator (SERM) that shows 10- to 60-fold increased affinity for the estrogen receptor compared with Tamoxifen. |
|
| DC21706 | STX3451 | A non-steroidal sulphamate analogue of 2-methoxyoestradiol (2ME2) and microtubule disruptor, shows anti-proliferative activity against NCI 60 cell lines with mean GI50 of 50 nM. |
|
| DC24034 | Coluracetam | A nootropic agent that enhances high-affinity choline uptake. |
|
| DC21342 | MPT0L145 | A nove potent, dual FGFR and PIK3C3 inhibitor with Kd of 0.53 nM for PIK3C3. |
|
| DC20550 | SHP2 inhibitor 2 | A nove potent, selective and reversible SHP2 inhibitor with Ki of 0.51 uM. |
|
| DC23493 | Ladarixin | A novel allosteric, noncompetitive dual CXCR1/2 inhibitor that inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8 in vitro with IC50 of 0.7 nM. |
|
| DC23467 | Ladarixin sodium | A novel allosteric, noncompetitive dual CXCR1/2 inhibitor that inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8 in vitro with IC50 of 0.7 nM. |
|
| DC20706 | AVN-211 | A novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM. |
|
| DC22565 | K-Ras G12C-IN-3 | A novel and irreversible inhibitor of mutant K-ras G12C.. |
|
| DC22572 | K-Ras G12C-IN-2 | A novel and irreversible inhibitor of mutant K-ras G12C.. |
|
| DC22573 | K-Ras G12C-IN-1 | A novel and irreversible inhibitor of mutant K-ras G12C.. |
|
| DC22587 | FT011 Featured | FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis. |
|
| DC22391 | Olorofim(F-901318) | Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp. |
|
| DC22507 | SCH-00013 | A novel cardiotonic agent that acts as a calcium sensitizer with no chronotropic activity in mammalian cardiac muscle, elicits positive inotropic effect in dog and rabbit ventricular muscles (EC50=9.2 uM). |
|
| DC22789 | 5S rRNA modificator 2 | A novel chemical probe that enable selective 2’-hydroxyl acylation for accurate RNA structural analysis in living cells.. |
|
| DC11521 | Dotinurad Featured | Dotinurad is a novel compound that exhibits a remarkable uric acid excretion-promoting action. |
|
| DC20796 | BIOD303 | A novel conformational modulator of α-synuclein with EC50 of 105 uM, potentially outcompetes spermine in binding to α-synuclein. |
|
| DC8784 | CTLA-4 inhibitor Featured | A novel CTLA-4 inhibitor. |
|
| DC22975 | GB111-NH2 Featured | GB111-NH2 (Z-Phe-Lys-AOMK) is a novel cysteine cathepsin inhibitor that blocks the activity of cathepsins B, L and S. GB111-NH2 (Z-Phe-Lys-AOMK) inhibits autophagy and increases oxidative stress, specifically trigger macrophage cell death. |
|
| DC22648 | VMY-1-103 | A novel dansylated analog of purvalanol B, and a CDK inhibitor that inhibits cell cycle progression and proliferation in prostate and breast cancer cells more effectively than purvalanol B. |
|
| DC20927 | CRS-3123 | A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI). |
|
| DC24099 | CC-115 hydrochloride | A novel dual inhibitor of mTOR and DNA-PK with IC50 of 21 nM and 13 nM, respectively. |
|
| DC21412 | SR-16157 | A novel dual-acting steroid sulfatase inhibitor (IC50=0.1 uM) and selective ERα modulator (SERM). |
|
| DC10706 | Ehp-inhibitor-2 Featured | A novel Ehp inhibitor |
|
| DC10705 | Ehp-inhibitor-1 Featured | A novel Ehp inhibitor |
|
| DC22487 | Benzenepentacarboxylic Acid Featured | Benzenepentacarboxylic acid is a fluorescent dye that detects and scavenge HO radicals. |
|
| DC22768 | MP07-66 Featured | A novel FTY720 analog that acts as PP2A activator, disrupts the SET/PP2A interaction devoid of immunosuppressive effects leads to the reactivation of PP2A. |
|
| DC23458 | AZD 9164 | A novel highly potent, selective, long acting muscarinic receptor M3 antagonist with pIC50 of 9.8, 10-fold selectivity over M2 (pIC50=9.0). |
|
