| DC71583 |
Fosimdesonide |
Fosimdesonide, a small molecule of adalimumab fosimdesonide, is a potent immunomodulator. Fosimdesonide shows anti-inflammatory activity. |
|
| DC71584 |
Opadotina |
Opadotina is a small molecule of anvatabart opadotin. Opadotina shows antineoplastic activity. |
|
| DC71585 |
Tazide |
Tazide is an antineoplastic agent. |
|
| DC71586 |
(R)-GNE-274 |
(R)-GNE-274 is a enantiomer of GNE-274. GNE-274 is a non-degrader that is structurally related to GDC-0927 (estrogen receptor degrader). |
|
| DC71587 |
Nifuraldezone-15N3 |
Nifuraldezone-15N3 is the 15N3 labeled Nifuraldezone. |
|
| DC71588 |
SRI-37330 hydrochloride
Featured
|
SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. SRI-37330 hydrochloride inhibits glucagon secretion and function, reduces hepatic glucose production and reverses hepatic steatosis. SRI-37330 hydrochloride can be used for type 2 diabetes research. |
|
| DC71589 |
Brogidirsen |
Brogidirsen exerts the stimulatory function of synthesis of functional dystrophin. |
|
| DC71590 |
(Rac)-CFT7455
Featured
|
(Rac)-CFT7455 is a zinc finger transcription factors Ikaros (IKZF1) and Aiolos (IKZF3) degrader, acting via the ubiquitin proteasome pathway, with a GI50 of 0.05 nM for NCIH929.1 cells. (Rac)-CFT7455 is the racemic isomer of CFT7455 which is a IKZF1/IKZF3 degrader with anticancer activity. |
|
| DC71591 |
1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d5 sodium |
1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d5 (sodium) is deuterium labeled 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine (sodium). |
|
| DC71592 |
C15 Ceramide-1-phosphate-d7 |
C15 Ceramide-1-phosphate-d7 is deuterium labeled C15 Ceramide-1-phosphate. |
|
| DC71593 |
15:0-18:1-15:0 TG-d5 |
15:0-18:1-15:0 TG-d5 is deuterium labeled 15:0-18:1-15:0 TG. |
|
| DC71594 |
Acloproxalap |
Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes. |
|
| DC71595 |
Ezurpimtrostat hydrochloride |
Ezurpimtrostat hydrochloride (compound 2-3) is a potent and orally active anti-fibrotic agent. Ezurpimtrostat hydrochloride reduces significantly the liver fibrosis in DEN (diethyl nitrosamine) cirrhotic rat model. Ezurpimtrostat hydrochloride can be used for the research of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases . |
|
| DC71596 |
Octocog alfa |
Octocog alfa is a second-generation full-length recombinant factor VIII, as a antihemophilic factor. |
|
| DC71597 |
Turoctocog alfa |
Turoctocog alfa is a recombinant coagulation factor VIII (FVIII) from chinese hamster ovary (CHO) cells. Turoctocog alfa can be used for researching haemophilia A. |
|
| DC71598 |
Reteplase |
Reteplase (BM 06.022) is a recombinant plasminogen activator, consists of the kringle 2 and protease domains of human tissue-type plasminogen activator. Reteplase is a t-PA mutant produced in Escherichia coli by DNA technology, and is unglycosylated. |
|
| DC71599 |
Lutropin |
Lutropin is a heterodimeric glycoprotein, a hormone produced by gonadotropic cells in the anterior pituitary gland, also known as luteinizing hormone and lutrophin. Lutropin stimulates follicular development, and can be used for researching infertility. |
|
| DC71600 |
Milrinone lactate |
Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock. |
|
| DC71601 |
GEMSA |
GEMSA is a potent inhibitor of enkephalin convertase (Ki=8.8 nM). GEMSA elicites analgesia. |
|
| DC71602 |
Fmoc-Lys(5-FITC)-OH |
Fmoc-Lys(5-FITC)-OH is a building block for in-sequence Lys labeling by FITC. FITC can be used to label peptides or proteins. |
|
| DC71603 |
FSG67 |
FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 of 24 μM. |
|
| DC71604 |
PNU-282987 S enantiomer free base |
PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base, which is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist. |
|
| DC71605 |
GSK-1520489A
Featured
|
GSK-1520489A(EX-A5430) is an active Protein Kinase, Membrane Associated Tyrosine/Threonine 1 (PKMYT1) inhibitor. |
|
| DC71606 |
(Rac)-IBT6A
Featured
|
IBT6A (BTK inhibitor 1) is an impurity of Ibrutinib, which is a Btk inhibitor (IC50=0.5 nM), and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. |
|
| DC71607 |
p-Nitrobenzyl mesylate |
p-Nitrobenzyl mesylate is an alkylating reagent for direct kinase substrate identification. |
|
| DC71608 |
Euquinine
Featured
|
Euquinine is generally used as a febrifuge, antimalarial, and tonic. |
|
| DC71609 |
Endoxifen E-isomer |
Endoxifen E-isomer (E-Endoxifen), an E-isomer of Endoxifen and impurity in Endoxifen Z-isomer drug substance, exhibits antiestrogenic effects. |
|
| DC71610 |
11-Mercaptoundecanoic acid |
11-Mercaptoundecanoic acid (MUA) is a thiol-containing fatty acid, which has been described in the preparation of self-assembled monolayers (SAMs), mixed monolayers, and metal-associated nanoparticles. |
|
| DC71611 |
TFMU-ADPr |
TFMU-ADPr is a general substrate for monitoring poly(ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr can directly report on total PAR hydrolase activity via release of a fluorophore. TFMU-ADPr has excellent reactivity, generality, stability, and usability. TFMU-ADPr is a versatile tool for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes. |
|
| DC71640 |
(-)Clausenamide |
(-)Clausenamide is an active alkaloid isolated from the leaves of Clausena lansium (Lour.) Skeels, and improves cognitive function in both normal physiological and pathological conditions. (-)Clausenamide inhibits β-amyloid (Aβ) toxicity, blocking neurofibrillary tangle formation by inhibiting the phosphorylation of tau protein. |
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