| DC71851 |
DIBAC-GGFG-NH2CH2-Dxd |
DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin derivative, is a linker-payload of protein-drug conjugates. |
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| DC71852 |
DM-Nitrophen |
DM-Nitrophen is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light. |
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| DC71853 |
DM-Nitrophen tertasodium |
DM-Nitrophen tertasodium is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light. DM-Nitrophen tertasodium can be used for study of Ca2+ signaling. |
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| DC71854 |
DMT-5Me-dC(Bz)-CE Phosphoramidite |
DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding. |
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| DC71855 |
Epirosmanol |
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity. |
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| DC71856 |
Etedesiran |
Etedesiran is a Myotonin-protein kinase (MT-PK, MDPK, or DMPK) inhibitor. |
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| DC71857 |
Euphoscopin C |
Euphoscopin C is a diterpenoid found in Euphorbia helioscopia. Euphoscopin C can significantly enhance the killing activity of NK cells against H1299 -luci cells and A549-luci cells. |
|
| DC71858 |
Ex26 |
Ex26 (S1P1-IN-Ex26) is a potent and selective Sphingosine 1-phosphate receptor 1 (S1P1) antagonist (IC50=0.93 nM). Ex26 shows >3,000-fold selectivity for S1P1 over other Sphingosine 1-phosphate receptors. Ex26 can be used in experimental autoimmune encephalomyelitis reseach. |
|
| DC71859 |
FEMA 4774 |
FEMA 4774 is a positive allosteric modulator of taste receptors T1R2 and T1R3, two subunits of the human sweet taste receptor. FEMA 4774 is also used as a sucrose sweetness enhancer. |
|
| DC71860 |
FLDP-8 |
FLDP-8 is a curcuminoid analogues, has potent anti-cancer effects. FLDP-8 can induce cell death with an IC50 value of 4 μM in LN-18 cells. |
|
| DC71861 |
Gd-NMC-3 |
Gd-NMC-3 is a near-infrared fluorescence/magnetic resonance (NIRF/MR) bimodal imaging probe. Gd-NMC-3 shows high resolution and sensitivity in tumor imaging with good biocompatibility, indicating huge application potential. |
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| DC71862 |
HG-7-85-01-NH2 |
HG-7-85-01-NH2 is the ligand of SNIPER(ABL)-033. SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 value of 0.3 μM. |
|
| DC71863 |
HITCI |
HITCI is a commercially available, positively charged, indocarbocyanine dye used typically as a laser dye in the near infrared (NIR) . |
|
| DC71864 |
Hydrocortisone phosphate sodium |
Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) can be used for the research for several ocular conditions and gastric ulcers. |
|
| DC71865 |
Imbotolimod |
Imbotolimod (trastuzumab imbotolimod), immunoglobulin G1-kappa, is a humanized monoclonal antibody with anti-ERBB2 and antineoplastic activity. Imbotolimod (trastuzumab imbotolimod) is a derivative of telratolimod . |
|
| DC71866 |
IR-990 |
IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H2O2 in vivo. IR-990 is a powerful diagnosis of drug-induced liver injury (DILI). |
|
| DC71867 |
JNJ-1289 |
JNJ-1289 is a potent, selective, competitive and allosteric human spermine oxidase (hSMOX) inhibitor (IC50: 50 nM). JNJ-1289 can be used in the research of polyamine catabolism, inflammation and cancers. |
|
| DC71868 |
Kobusine derivative-1 |
Kobusine derivative-1 is a Kobusine derivative. Kobusine derivative-1 shows antiproliferative activities against cancer cells. |
|
| DC71869 |
Kobusine derivative-2 |
Kobusine derivative-2, a kobusine derivative, has antiproliferative activity against cancer cells. Kobusine derivative-2 can induce the arrest of MDA-MB-231 cells in the sub-G1 phase. Anticancer activity. |
|
| DC71870 |
Leteprinim potassium |
Leteprinim potassium (AIT-082) is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species. Leteprinim potassium has neuroprotective activity. |
|
| DC71871 |
l-Naproxen |
l-Naproxen ((R)-Naproxen) is an enantiomer of (S)-Naproxen. l-Naproxen can inhibit Cdc42 and Rac1 (EC50=96 μM and 212 μM, respectively), and show anti-tumor activity. |
|
| DC71872 |
Melitracen |
Melitracen is an orally active tricyclic antidepressant and it is also a bipolar thymoleptic with activating properties. Melitracen inhibits 3H-5-HT and 14H-5-HT with IC50s of 670 nM and 5500 nM, respectively. Melitracen can be used for the research of depression and anxiety. |
|
| DC71873 |
Mem-C1C18 |
Mem-C1C18 is a polarity-sensitive fluorescent probe with excellent plasma membrane anchoring, high brightness and a sensitive response to environmental polarity by altering the fluorescence lifetime. Mem-C1C18 can be used to quantify changes in the polarity of the plasma membrane during iron death. |
|
| DC71874 |
MIF098
Featured
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MIF098 is a macrophage migration inhibitory factor (MIF) antagonist. MIF098 inhibits proliferation, migration and fibrosis of pulmonary smooth muscle cells. MIF098 can be used for immunoinflammation-related disease research. |
|
| DC71875 |
Milpocitide |
Milpocitide is a low-density lipoprotein receptor (human LDL receptor, LDLR), (293-333)-peptide fragment (EGF-like domain 1). |
|
| DC71876 |
Nelutroctiv |
Nelutroctiv is a potent cardiac troponin activator. |
|
| DC71877 |
N-Formylsarcolysine |
N-Formylsarcolysine has antitumor activity, and inhibits leukemia by increasing the Hb and erythrocyte levels and decreasing the number of leukocytes. N-Formylsarcolysine also involves in glioblastoma and other diseases research. |
|
| DC71878 |
NR2F6 modulator-1 |
NR2F6 modulator-1 is a potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator. NR2F6 modulator-1 can be used for researching immune modulation and modulation of cancer stem cell activity. |
|
| DC71879 |
Odetiglucan |
Odetiglucan, a novel beta glucan, is a potent immunostimulant. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response. |
|
| DC71880 |
Oseltamivir acid methyl ester |
Oseltamivir acid methyl ester is a prodrug form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester is converted to oseltamivir acid by carboxylesterase 1 (CES1) . |
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