| DC71654 |
WAY-297848 |
WAY-297848 is a novel glucokinase activator with potential use as a drug for the prevention or treatment of hyperglycemia, diabetes, obesity, dyslipidemia, metabolic syndrome, etc. |
|
| DC71660 |
K027 |
K027 is a potent reactivator of Organophosphates (OP)-inhibited acetylcholinesterase (AChE). K027 can be used for the research of Alzheimer's disease. |
|
| DC71670 |
KR-39038 |
KR-39038 is an orally active and potent GRK5 (G protein-coupled receptor kinase 5) inhibitor, with an IC50 of 0.02 μM. KR-39038 significantly inhibits angiotensin II-induced cellular hypertrophy through suppression of HDAC5 pathway in neonatal cardiomyocytes. KR-39038 shows profound anti-hypertrophic effects and improved cardiac function. KR-39038 can be used for heart failure research. |
|
| DC71684 |
TM-1 |
TM-1 is a potent inhibitor of pyruvate dehydrogenase kinase (PDHK1). TM-1 inhibits PDHK1 and PDHK2 with IC50s of 2.97 μM and 5.2 μM, respectively. TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation, and inhibits cell proliferation. |
|
| DC71685 |
Dioleoylphosphatidylglycerol |
Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) . |
|
| DC71686 |
Decanoic acid, 2-hexyl-, 6-oxohexyl ester-1
Featured
|
Decanoic acid, 2-hexyl-, 6-oxohexyl ester-1 is a lipid product can be used for drug delivery. |
|
| DC71689 |
K145
Featured
|
K145 is a selective, substrate-competitive and orally active sphingosine kinase-2 (SphK2) inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM in biochemical assays. |
|
| DC71694 |
Diphenyl-1-pyrenylphosphine |
Diphenyl-1-pyrenylphosphine (DPPP) is a fluoregenic peroxide reactive probe. Diphenyl-1-pyrenylphosphine exhibits a unique phototriggered aggregation-induced emission (AIE)/aggregation-induced quenching (ACQ) transition with a remarkable third-order nonlinear optical signal change. |
|
| DC71696 |
Palmitoyloleoylphosphatidylglycerol |
Palmitoyloleoylphosphatidylglycerol is an anionic surfactant lipid. Palmitoyloleoylphosphatidylglycerol suppresses Der p 2-stimulated inflammatory responses in lung epithelial cells and macrophages. |
|
| DC71697 |
DHAPC
Featured
|
DHAPC is a phospholipid that is very sensitive to oxidation. |
.jpg)
|
| DC71699 |
DOIC
Featured
|
DOIC is a cationic lipid that can be used for RNA vaccines. |
|
| DC71700 |
Lumogallion |
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm. |
|
| DC71701 |
Elosulfase alfa |
Elosulfase alfa (BMN 110) is a recombinant form of human N-acetylgalactosamine-6-sulfatase (GALNS). Elosulfase alfa is used as an enzyme replacement therapy for mucopolysaccharidosis IVA (MPS IVA), also known as Morquio A syndrome. |
|
| DC71833 |
(1R,2S)-Xeruborbactam disodium |
(1R,2S)-Xeruborbactam ((1R,2S)-QPX7728) disodium is a boronic acid derivative. |
|
| DC71834 |
(R)-FL118 |
(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118. (R)-FL118 shows anticancer activity. |
|
| DC71835 |
(R)-RP-6306
Featured
|
(R)-RP-6306 (183) can be used for the research of Myt1 mediated diseases and kinds of cancer for slowing the progression of cancer. |
|
| DC71836 |
DOPA-NA
Featured
|
DOPA-NA is an anionic lipid that can be used to prepare liposomes, micelles and artificial membranes. |
|
| DC71837 |
16-Azidohexadecanoic acid |
16-Azidohexadecanoic acid, a synthetic fatty acid, can be used as a modification marker for nucleotides and a molecular probe for fatty acid metabolism. |
|
| DC71838 |
1H-1-Ethyl Candesartan Cilexetil |
1H-1-Ethyl Candesartan Cilexetil is a potential impurity found in bulk preparations of Candesartan Cilexetil. |
|
| DC71839 |
1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium |
Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product generated following activation of the NADPH oxidase and lyso-PS signaling. Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium through the macrophage G2A functions to enhance existing receptor/ligand systems for resolution of neutrophilic inflammation. |
|
| DC71840 |
5-(3-Hydroxybenzylidene)-rhodanine |
5-(3-Hydroxybenzylidene)-rhodanine, a derivative of rhodanine, can be used as an algicidal agent. |
|
| DC71841 |
Acifluorfen-methyl |
Acifluorfen-methyl is an inhibitor of the heme and chlorophyll biosynthetic enzyme protoporphyrinogen oxidase (Protox). Acifluorfen-methyl is a photobleaching herbicide. |
|
| DC71842 |
AS1134900 |
AS1134900 is a highly selective, allosteric and uncompetitive NADP+-dependent malic enzyme 1 (ME1) inhibitor. |
|
| DC71843 |
BAY 1135626
Featured
|
BAY 1135626 is used to synthesize BAY 1129980, and use to anti-tumor research. BAY 1129980 is a Auristatin-based anti-C4.4A (LYPD3) antibody–drug conjugate (ADC), is used to non–small cell lung cancer (NSCLC) research. |
|
| DC71844 |
Belatacept |
Belatacept (BMS 224818) is a selective T-cell costimulation blocker. Belatacept binds to CD 80/86 ligands and thereby inhibits the CD-28-mediated T-cell costimulation. Belatacept can be used in the research of Immunosuppression in organ transplants. |
|
| DC71845 |
Berberine ursodeoxycholate |
Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent hypolipidemic agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes. |
|
| DC71846 |
Bocconoline |
Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD). |
|
| DC71848 |
Cedazuridine hydrochloride |
Cedazuridine (E7727) (Compound 7a) hydrochloride is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine hydrochloride can be used for cancer research. |
|
| DC71849 |
Colestilan |
Colestilan (MCI-196) is a non-absorbed, non-calcium-based phosphate binder and is also a non-metallic, anion exchange resin. Colestilan is orally active and can be used for hypercholesterolaemia research. |
|
| DC71850 |
DB772 hydrate |
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity. |
|
